TY  - JOUR
A1  - Masota, Nelson E.
A1  - Vogg, Gerd
A1  - Heller, Eberhard
A1  - Holzgrabe, Ulrike
T1  - Comparison of extraction efficiency and selectivity between low‐temperature pressurized microwave‐assisted extraction and prolonged maceration
T2  - Archiv der Pharmazie
N2  - Extraction is a key step in studying compounds from plants and other natural sources. The common use of high temperatures in pressurized microwave‐assisted extraction (PMAE) makes it unsuitable for the extraction of compounds with low or unknown thermal stability. This study aimed at determining the suitability of low‐temperature, short‐time PMAE in attaining yields comparable to those of prolonged maceration at room temperature. Additionally, we explored the phytochemical differences of the extracts from both techniques. Maceration at room temperature for 24 hr and PMAE at 40–45°C and 10 bar for 30 min were carried out on 18 samples from 14 plant species at a solvent‐to‐feeds ratio of 10. The PMAE yields of 16 out of 18 samples were within the proportions of 91–139.2% as compared with the respective extracts from maceration. Varying numbers of nonmatching peaks were noted in MS chromatograms of five extract pairs, indicating selective extraction of some compounds. Low‐temperature PMAE can attain reasonable extraction efficiency with the added value of sparing compounds of low thermal stability. The method can also enable the recovery of compounds distinct from those obtained by maceration.
KW  - extraction
KW  - HPLC–MS
KW  - maceration
KW  - pressurized microwave‐assisted extraction
Y1  - 2020
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/21852
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-218529
VL  - 353
IS  - 10
ER  -