TY  - JOUR
A1  - Dietzsch, Julia
A1  - Bialas, David
A1  - Bandorf, Johannes
A1  - Würthner, Frank
A1  - Höbartner, Claudia
T1  - Tuning Exciton Coupling of Merocyanine Nucleoside Dimers by RNA, DNA and GNA Double Helix Conformations
T2  - Angewandte Chemie International Edition
N2  - Exciton coupling between two or more chromophores in a specific environment is a key mechanism associated with color tuning and modulation of absorption energies. This concept is well exemplified by natural photosynthetic proteins, and can also be achieved in synthetic nucleic acid nanostructures. Here we report the coupling of barbituric acid merocyanine (BAM) nucleoside analogues and show that exciton coupling can be tuned by the double helix conformation. BAM is a nucleobase mimic that was incorporated in the phosphodiester backbone of RNA, DNA and GNA oligonucleotides. Duplexes with different backbone constitutions and geometries afforded different mutual dye arrangements, leading to distinct optical signatures due to competing modes of chromophore organization via electrostatic, dipolar, - stacking and hydrogen-bonding interactions. The realized supramolecular motifs include hydrogenbonded BAM–adenine base pairs and antiparallel as well as rotationally stacked BAM dimer aggregates with distinct absorption, CD and fluorescence properties.
KW  - Chromophore Assembly
KW  - Merocyanine
KW  - Nucleobase Analogue
KW  - Supramolecular Element
KW  - Nucleic Acids
Y1  - 2022
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/25456
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-254565
ER  -