TY - CONF A1 - Anders, F. A1 - Scholl, E. A1 - Schartl, Manfred T1 - Environmental and hereditary factors in the causation of neoplasia, based on studies of the Xiphophorus fish melanoma system N2 - Neoplasia in Xiphophorus can be classified into: a) a Jarge group triggered by carcinogens; b) a large group triggered by promoters; and c) a small group that develops "spontaneously" according to Mendelian Jaw. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Interpopulational arid interracial hybridization is the most effective process that Ieads to disintegration of the protective gene systems. Environmental factors may complete disintegration in somatic cells and thus may trigger neoplasia. The applications of the findings on Xiphophorus to humans are discussed. KW - Schwertkärpfling KW - Gen KW - Umweltfaktor KW - Tumor Y1 - 1981 UR - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/7273 UR - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-86402 ER -