TY - JOUR A1 - Marre, R. A1 - Kreft, B. A1 - Hacker, Jörg T1 - Genetically engineered S and F1C fimbriae differ in their contribution to adherence of Escherichia coli to cultured renal tubular cells N2 - Escherichia coU K-12 strains producing S-fimbrial adhesins, FlC fimbriae, and mutagenized fimbriae were tested in a binding assay with a renal tubular cell line. S-fimbrial adhesins and FlC fimbriae mediated bindlog to tubular cells. The SfaA, SfaG, and SfaS subunits of S fimbriae contributed to attachment. Site-specific mutations in the sfaS gene reduced binding. The Inhibitionprofile of FlC fimbriae resembled that of S fimbriae. KW - Infektionsbiologie Y1 - 1990 UR - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/5289 UR - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-59644 ER -