TY  - JOUR
A1  - Werner, Rudolf A.
T1  - Editorial: Cardiac Innervation Imaging as a Risk Stratification Tool for Potential Device Therapy Candidates
T2  - Journal of Nuclear Cardiology
N2  - As a scintigraphic approach evaluating cardiac nerve integrity, \(^{123}\)I-metaiodobenzylguanidine (123I-mIBG) has been recently Food and Drug Administration approved. A great deal of progress has been made by the prospective ADMIRE-HF trial, which primarily demonstrated the association of denervated myocardium assessed by \(^{123}\)I-mIBG and cardiac events. However, apart from risk stratification, myocardial nerve function evaluated by molecular imaging should also be expanded to other clinical contexts, in particular to guide the referring cardiologist in selecting appropriate candidates for specific therapeutic interventions. In the present issue of the Journal of Nuclear Cardiology, the use of 123I-mIBG for identifying cardiomyopathy patients, which would most likely not benefit from ICD due low risk of arrhythmias, is described. If we aim to deliver on the promise of cardiac innervation imaging as a powerful tool for risk stratification in a manner similar to nuclear oncology, studies such as the one reviewed here may imply an important step to lay the proper groundwork for a more widespread adoption in clinical practice.
KW  - SPECT
KW  - SPECT
KW  - myocardial nerve
KW  - 123I-metaiodobenzylguanidine
KW  - 123I-mIBG
KW  - cardiac nerve
KW  - ICD
KW  - arrhythmia
KW  - cardiac innervation imaging
Y1  - 2018
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/16846
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-168465
UR  - https://rdcu.be/970i
SN  - 1071-3581
N1  - SharedIt-Link zur Publikation: 
https://rdcu.be/970i
N1  - This is a post-peer-review, pre-copyedit version of an article published in Journal of Nuclear Cardiology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s12350-018-01475-0
ER  -