TY  - JOUR
A1  - Ott, M.
A1  - Hacker, Jörg
T1  - Analysis of the variability of S fimbriae expression in an Escherichia coli pathogen.
N2  - The uropathogenic Escherichia coli wiJd..:type strain 536 produces S-fimbriae, P-related fimbriae and type I fimbriae. Using immuno-colony dot and ELISA techniques, variants were detected showing an increased degree of S-fimbrial production. It was demonstrated by itrtmunofluorescence microscopy that in noimal (wild-type) and hyperS- fimbriated E. coli populaiions non-fimbriated cells also · exist, and that the percentage of Sfinibrlated and non-fimbriated bacteria was roughly identica1 in either population. Hyper-Sfimbriated variants could be stably maintained. The transition from wild-type to hyper-S-fimbriation, which occurs spontaneously, is markedly higher than vice versa. Southern blot analysis of the S fimbrial adhesin (sfa) determinants of normal and hyper-fimbriated strains revealed no marked difference in the gene structure.
KW  - Infektionsbiologie
KW  - Escherichia coli
KW  - S-fimbria
KW  - Variability
KW  - Expression
Y1  - 1991
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/5297
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-59695
ER  -