TY  - JOUR
A1  - Schmitt, Elke
A1  - Meybohm, Patrick
A1  - Neef, Vanessa
A1  - Baumgarten, Peter
A1  - Bayer, Alexandra
A1  - Choorapoikayil, Suma
A1  - Friederich, Patrick
A1  - Friedrich, Jens
A1  - Geisen, Christof
A1  - Güresir, Erdem
A1  - Grünewald, Matthias
A1  - Gutjahr, Martin
A1  - Helmer, Philipp
A1  - Herrmann, Eva
A1  - Müller, Markus
A1  - Narita, Diana
A1  - Raadts, Ansgar
A1  - Schwendner, Klaus
A1  - Seifried, Erhard
A1  - Stark, Patrick
A1  - Steinbicker, Andrea U.
A1  - Thoma, Josef
A1  - Velten, Markus
A1  - Weigt, Henry
A1  - Wiesenack, Christoph
A1  - Wittmann, Maria
A1  - Zacharowski, Kai
A1  - Piekarski, Florian
T1  - Preoperative anaemia and red blood cell transfusion in patients with aneurysmal subarachnoid and intracerebral haemorrhage - a multicentre subanalysis of the German PBM Network Registry
T2  - Acta Neurochirurgica
N2  - Purpose
Anaemia is common in patients presenting with aneurysmal subarachnoid (aSAH) and intracerebral haemorrhage (ICH). In surgical patients, anaemia was identified as an idenpendent risk factor for postoperative mortality, prolonged hospital length of stay (LOS) and increased risk of red blood cell (RBC) transfusion. This multicentre cohort observation study describes the incidence and effects of preoperative anaemia in this critical patient collective for a 10-year period.

Methods
This multicentre observational study included adult in-hospital surgical patients diagnosed with aSAH or ICH of 21 German hospitals (discharged from 1 January 2010 to 30 September 2020). Descriptive, univariate and multivariate analyses were performed to investigate the incidence and association of preoperative anaemia with RBC transfusion, in-hospital mortality and postoperative complications in patients with aSAH and ICH.

Results
A total of n = 9081 patients were analysed (aSAH n = 5008; ICH n = 4073). Preoperative anaemia was present at 28.3% in aSAH and 40.9% in ICH. RBC transfusion rates were 29.9% in aSAH and 29.3% in ICH. Multivariate analysis revealed that preoperative anaemia is associated with a higher risk for RBC transfusion (OR = 3.25 in aSAH, OR = 4.16 in ICH, p < 0.001), for in-hospital mortality (OR = 1.48 in aSAH, OR = 1.53 in ICH, p < 0.001) and for several postoperative complications.

Conclusions
Preoperative anaemia is associated with increased RBC transfusion rates, in-hospital mortality and postoperative complications in patients with aSAH and ICH.
KW  - aneurysmal subarachnoid haemorrhage
KW  - intracerebral haemorrhage
KW  - anaemia
KW  - red blood cell transfusion
KW  - patient blood management
Y1  - 2022
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/34675
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-346754
VL  - 164
ER  -