TY  - JOUR
A1  - Matthies, Cordula
A1  - Brill, Stefan
A1  - Kaga, Kimitaka
A1  - Morita, Akio
A1  - Kumakawa, Kozo
A1  - Skarzynski, Henryk
A1  - Claassen, Andre
A1  - Hui, Yau
A1  - Chiong, Charlotte
A1  - Müller, Joachim
A1  - Behr, Robert
T1  - Auditory Brainstem Implantation Improves Speech Recognition in Neurofibromatosis Type II Patients
T2  - ORL
N2  - This prospective study aimed to determine speech understanding in neurofibromatosis type II (NF2) patients following implantation of a MED-EL COMBI 40+ auditory brainstem implant (ABI). Patients (n = 32) were enrolled postsurgically. Nonauditory side effects were evaluated at fitting and audiological performance was determined using the Sound Effects Recognition Test (SERT), Monosyllable-Trochee-Polysyllable (MTP) test and open-set sentence tests. Subjective benefits were determined by questionnaire. ABI activation was documented in 27 patients, 2 patients were too ill for testing and 3 patients were without any auditory perception. SERT and MTP outcomes under auditory-only conditions improved significantly between first fitting and 12-month follow-up. Open-set sentence recognition improved from 5% at first fitting to 37% after 12 months. The number of active electrodes had no significant effect on performance. All questionnaire respondents were ‘satisfied' to ‘very satisfied' with their ABI. An ABI is an effective treatment option in NF2 patients with the potential to provide open-set speech recognition and subjective benefits. To our knowledge, the data presented herein is exceptional in terms of the open-set speech perception achieved in NF2 patients.
KW  - acoustic neuroma
KW  - auditory brainstem implant
KW  - nonauditory side effects
KW  - open-set sentence recognition
KW  - subjective benefits
KW  - vestibular schwannoma
Y1  - 2013
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/19638
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-196383
SN  - 0301-1569
SN  - 1423-0275
N1  - This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
VL  - 75
IS  - 5
ER  -