TY  - JOUR
A1  - Geffers, Martha
A1  - Groll, Jürgen
A1  - Gbureck, Uwe
T1  - Reinforcement strategies for load-bearing calcium phosphate biocements
T2  - Materials
N2  - Calcium phosphate biocements based on calcium phosphate chemistry are well-established biomaterials for the repair of non-load bearing bone defects due to the brittle nature and low flexural strength of such cements. This article features reinforcement strategies of biocements based on various intrinsic or extrinsic material modifications to improve their strength and toughness. Altering particle size distribution in conjunction with using liquefiers reduces the amount of cement liquid necessary for cement paste preparation. This in turn decreases cement porosity and increases the mechanical performance, but does not change the brittle nature of the cements. The use of fibers may lead to a reinforcement of the matrix with a toughness increase of up to two orders of magnitude, but restricts at the same time cement injection for minimal invasive application techniques. A novel promising approach is the concept of dual-setting cements, in which a second hydrogel phase is simultaneously formed during setting, leading to more ductile cement-hydrogel composites with largely unaffected application properties.
KW  - in vitro
KW  - synergistic reinforcement
KW  - dihydrate cement
KW  - porosity
KW  - mechanical properties
KW  - dual setting
KW  - calcium phosphate cements
KW  - fiber reinforcement
KW  - polyacrylic acid
KW  - compressive strength
KW  - balloon kyphoplasty
KW  - brushite cement
KW  - bone cement
Y1  - 2015
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/14863
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-148636
VL  - 8
ER  -