TY  - JOUR
A1  - Kämmerer, Ulrike
A1  - Klement, Rainer J.
A1  - Joos, Fabian T.
A1  - Sütterlin, Marc
A1  - Reuss-Borst, Monika
T1  - Low carb and ketogenic diets increase quality of life, physical performance, body composition, and metabolic health of women with breast cancer
T2  - Nutrients
N2  - Breast cancer (BC) patients often ask for a healthy diet. Here, we investigated a healthy standard diet (SD), a low carb diet (LCD), and a ketogenic diet (KD) for BC patients during the rehabilitation phase. KOLIBRI was an open-label non-randomized one-site nutritional intervention trial, combining inpatient and outpatient phases for 20 weeks. Female BC patients (n = 152; mean age 51.7 years) could select their diet. Data collected were: Quality of life (QoL), spiroergometry, body composition, and blood parameters. In total 30, 92, and 30 patients started the KD, LCD, and SD, respectively. Of those, 20, 76, and 25 completed the final examination. Patients rated all diets as feasible in daily life. All groups enhanced QoL, body composition, and physical performance. LCD participants showed the most impressive improvement in QoL aspects. KD participants finished with a very good physical performance and muscle/fat ratio. Despite increased cholesterol levels, KD patients had the best triglyceride/high-density lipoprotein (HDL) ratio and homeostatic model assessment of insulin resistance index (HOMA-IR). Most metabolic parameters significantly improved in the LCD group. SD participants ended with remarkably low cholesterol levels but did not improve triglyceride/HDL or HOMA-IR. In conclusion, both well-defined KDs and LCDs are safe and beneficial for BC patients and can be recommended during the rehabilitation phase.
KW  - breast cancer
KW  - rehabilitation
KW  - ketogenic diet
KW  - low carb diet
KW  - supportive care
Y1  - 2021
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/23420
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-234209
SN  - 2072-6643
VL  - 13
IS  - 3
ER  -