TY  - JOUR
A1  - Streck, Laura Elisa
A1  - Gaal, Chiara
A1  - Forster, Johannes
A1  - Konrads, Christian
A1  - Hertzberg-Boelch, Sebastian Philipp von
A1  - Rueckl, Kilian
T1  - Defining a synovial fluid white blood cell count threshold to predict periprosthetic infection after shoulder arthroplasty
T2  - Journal of Clinical Medicine
N2  - Background: The diagnosis of periprosthetic shoulder infection (PSI) requires a thorough diagnostic workup. Synovial fluid aspiration has been proven to be a reliable tool in the diagnosis of joint infections of the lower extremity, but shoulder specific data is limited. This study defines a threshold for synovial fluid white blood cell count (WBC) and assesses the reliability of microbiological cultures. Methods: Retrospective study of preoperative and intraoperative fluid aspiration of 31 patients who underwent a revision of a shoulder arthroplasty (15 with PSI defined by IDSA criteria, 16 without infection). The threshold for WBC was calculated by ROC/AUC analysis. Results: WBC was significantly higher in patients with PSI than in other patients. A threshold of 2800 leucocytes/mm\(^3\) showed a sensitivity of 87% and a specificity of 88% (AUROC 0.92). Microbiological cultures showed a sensitivity of 76% and a specificity of 100%. Conclusions: A threshold of 2800 leucocytes/mm\(^3\) in synovial fluid can be recommended to predict PSI. Microbiological culture has an excellent specificity and allows for targeted antibiotic therapy. Joint aspiration presents an important pillar to diagnose PSI.
KW  - upper extremity
KW  - joint infection
KW  - joint aspiration
KW  - leucocyte count
KW  - cutibacteria
KW  - ICM
KW  - MSIS
KW  - IDSA
KW  - WBC
Y1  - 2021
UR  - https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/25227
UR  - https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-252275
SN  - 2077-0383
VL  - 11
IS  - 1
ER  -