@article{TackeWagnerBrakmannetal.1993,
  author    = {Tacke, Reinhold and Wagner, S. A. and Brakmann, S. and Wuttke, F. and Eilert, U. and Fischer, L. and Syldatk, C.},
  title     = {Synthesis of acetyldimethyl(phenyl)silane and its enantioselective conversion into (R)-(1-hydroxyethyl)dimethyl(phenyl)silane by plant cell suspension culytures of Symphytum officinale L. and Ruta graveolens L.},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-64299},
  year      = {1993},
  abstract  = {Starting from chlorodimethyl(phenyl)silane (3), acetyldimethyl(phenyl)silane (l) was prepared by a two-step synthesis in a total yield of 90\% [PhMe\(_2\)SiCl (3)-> PhMe\(_2\)SiCCOMe)=CH\(_2\) (4)-> PhMe\(_2\)SiC(O)Me (1)]. The prochiral acetylsilane 1 was transfonned enantioselectively into (R)-(1-hydroxyethyl)dimethyl(phenyl)silane [(R)-2] using plant cell Suspension cultures of Symphytum officinale L. or Ruta graveolens L. Under preparative conditions (300-mg scale, not optimized), (R)-2 was isolated in 15\% (Symphytum) and 9\% yield (Ruta), respectively. The enantiomeric purities of the products were 81\% ee (Syrnphytum) and 60\% ee (Ruta), respectively.},
  subject      = {Anorganische Chemie},
  language  = {en}
}