@article{ScheerSchmidtZachmannHuegleetal.1984,
  author    = {Scheer, Ulrich and Schmidt-Zachmann, Marion S. and H{\"u}gle, Barbara and Franke, Werner W.},
  title     = {Identification and localization of a novel nucleolar protein of a high molecular weight by a monoclonal antibody},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39786},
  year      = {1984},
  abstract  = {A monoclonal murine antibody (No-I 14) is described which reacts specifically with a polypeptide of molecular weight (M,) 180000 present in low-speed nuclear pellets from oocytes and somatic cells of Xenopus laevis and X. borealis and in isolated amplified nucleoli. Two-dimensional gel electrophoresis has revealed the acidic nature of this polypeptide (isoelectric at pH of ca 4.2 in the presence of 9.5 M urea). A relatively large proportion of the protein is extracted at elevated ionic strength( i.e., at 0.4-0.5 M alkali salt) in a form sedimenting at approx. 7-8S , compatible with a monomeric state. It is also extracted by digestion with RNase but not with DNase. In immunofluorescence microscopy, antibody No-114 stains intensely nucleoli of oocytes and all somatic cells examined , including the residual nucleolar structure of Xenopus erythrocytes which are transcriptionally inactive. During mitosis the antigen does not remain associated with the nucleolar organizer regions (NOR) of chromosomes but is released and dispersed over the cytoplasm until telophase when it re-associates with the reforming interphase nucleoli. At higher resolution the immunofluorescent region is often resolved into a number of distinct subnucleolar components of varied size and shape. Immunoelectron microscopy using colloidal gold-coupled secondary antibodies reveals that the M, 180000 protein is confined to the dense fibrillar component of the nucleolus. This conclusion is also supported by its localization in the fibrillar part of segregated nucleoli of cells treated with actinomycin D. We conclude that nucleoli contain a prominent protein of M, 180000 which contributes to the general structure of the dense fibrillar component of the interphase nucleolus , independent of its specific transcriptional activity.},
  language  = {en}
}
@article{Schuessler1988,
  author    = {Sch{\"u}ssler, Ulrich},
  title     = {Mobilisation einzelner Elemente in Amphiboliten aus der Umgebung der KTB-Lokation, Zone Erbendorf-Vohenstrauss, n{\"o}rdliche Oberpfalz},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39248},
  year      = {1988},
  abstract  = {No abstract available},
  subject      = {Mineralogie},
  language  = {de}
}
@article{ThiryScheerGoessens1991,
  author    = {Thiry, Marc and Scheer, Ulrich and Goessens, Guy},
  title     = {Localization of nucleolar chromatin by immunocytochemistry and in situ hybridization at the electron microscopic level},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39289},
  year      = {1991},
  abstract  = {Nucleoli are the morphological expression of the activity of a defined set of chromosomal segments bearing rRNA genes. The topological distribution and composition of the intranucleolar chromatin as well as the definition of nucleolar structures in which enzymes of the rDNA transcription machinery reside have been investigated in mammalian cells by various immunogold labelling approaches at the ultrastructural level. The precise intranucleolar location of rRNA genes has been further specified by electron microscopic in situ hybridization with a non-autoradiographic procedure. Our results indicate that the fibrillar centers are the sole nucleolar structures where rDNA, core histones, RNA polymerase I and DNA to po isomerase I are located together. Taking into account the potential value and limitations of immunoelectron microscopic techniques, we propose that transcription of the rRNA genes takes place within the confines of the fibrillar centers, probably close to the boundary regions to the surrounding dense fibrillar component.},
  language  = {en}
}
@article{GesslerKoenigArdenetal.1994,
  author    = {Gessler, Manfred and K{\"o}nig, A. and Arden, K. and Grundy, P. and Orkin, S. H. and Sallan, S. and Peters, C. and Ruyle, S. and Mandell, J. and Li, F. and Cavenee, W. and Bruns, G. A.},
  title     = {Infrequent mutation of the WT1 gene in 77 Wilms' Tumors},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-34308},
  year      = {1994},
  abstract  = {Homozygous deletions in Wilms' tumor DNA have been a key step in the identification and isolation of the WTI gene. Several additional loci are also postulated to contribute to Wilms' tumor formation. To assess the frequency of WTI alterations we have analyzed the WTI locus in a panel of 77 Wilms' tumors. Eight tumors showed evidence for large deletions of several hundred or thousand kilobasepairs of DNA, some of which were also cytogenetically detected. Additional intragenic mutations were detected using more sensitive SSCP analyses to scan all 10 WTI exons. Most of these result in premature stop codons or missense mutations that inactivate the remaining WTI allele. The overall frequency of WTI alterations detected with these methods is less than 15\%. While some mutations may not be detectable with the methods employed, our results suggest that direct alterations of the WTI gene are present in only a small fraction of Wilms' tumors. Thus, mutations at other Wilms' tumor loci or disturbance of interactions between these genes likely play an important role in Wilms' tumor development.},
  language  = {en}
}
@article{Ellgring1992,
  author    = {Ellgring, Johann Heinrich},
  title     = {Psychosoziale Aspekte des Morbus Parkinson},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-34052},
  year      = {1992},
  abstract  = {No abstract available},
  language  = {de}
}
@article{Koenig1984,
  author    = {K{\"o}nig, Dorothea},
  title     = {Materialien zu den Fragmenten des Mihanovic-Homiliars},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-38566},
  year      = {1984},
  abstract  = {No abstract available},
  language  = {ru}
}
@article{Koenig1986,
  author    = {K{\"o}nig, Dorothea},
  title     = {Materialien zu den Fragmenten des Mihanovic-Homiliars},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-38599},
  year      = {1986},
  abstract  = {No abstract available},
  language  = {ru}
}
@article{Koenig1974,
  author    = {K{\"o}nig, Dorothea},
  title     = {Notizen zum Wortschatz des Vatikanski Hrvatski Molitvenik},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-38740},
  year      = {1974},
  abstract  = {No abstract available},
  language  = {de}
}
@article{KoenigAitzetmueller1987,
  author    = {K{\"o}nig, Dorothea and Aitzetmueller, Rudolf},
  title     = {Die Slavistik an der Universit{\"a}t W{\"u}rzburg},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-38778},
  year      = {1987},
  abstract  = {No abstract available},
  language  = {de}
}
@article{Hee2009,
  author    = {Hee, Katrin},
  title     = {Nicht Tabu},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39075},
  year      = {2009},
  abstract  = {Dieser Artikel beschreibt eine Unterrichtssequenz f{\"u}r den Deutschunterricht im Bereich Deutsch als Fremdsprache und richtet sich an Lernende der Niveaustufe A2. Er zeigt, wie Lernende spielerisch sowohl rezeptive Sprachkenntnisse als auch aktive Sprachbeherrschung verbessern und ihren Wortschatz erweitern k{\"o}nnen. Ein besonders wichtiges Kriterium sind dabei der Spielcharakter und die Auflockerung des Unterrichts, sowie die M{\"o}glichkeit, individuell auf die Bed{\"u}rfnisse der Studenten eingehen zu k{\"o}nnen.},
  subject      = {Wortschatz},
  language  = {de}
}