@article{WiegeringSchlegelWinkleretal.2015, author = {Wiegering, V. and Schlegel, P. G. and Winkler, B. and Lazarus, M. and Wirth, C. and Ernestus, K. and Walles, T. and Liese, J.}, title = {Persisting Cough as the Single Presenting Symptom of an Intrathoracic Tumor in a Nine-Month-Old Child with Adenovirus Airway Infection}, series = {Journal of Case Reports and Studies}, volume = {3}, journal = {Journal of Case Reports and Studies}, number = {2}, doi = {10.15744/2348-9820.2.504}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-125536}, pages = {204}, year = {2015}, abstract = {We report on a nine-month-old girl who presented with persisting cough, and diminished ventilation of the left hemithorax. Viral pneumonia was suspected after Adenovirus detection by PCR, but chest X-rays showed a persistent shadowing of the left hemithorax and persistent coughing despite clinical improvement. Because of the discrepancy between clinical and radiological signs further investigations by ultrasound and CT scan were performed, which visualized an intrathroracic tumor. Histopathology confirmed diagnosis of a teratoma. This case highlights the need for careful evaluation by the treating physicians. If the chest X-ray provides a discrepancy to the clinical findings or persistent pathologies exist, differential diagnosis should be discussed and further diagnostics be performed.}, language = {en} } @article{SauerbreiLangenhanBrandstaedtetal.2014, author = {Sauerbrei, A. and Langenhan, T. and Brandst{\"a}dt, A. and Schmidt-Ott, R. and Krumbholz, A. and Girschick, H. and Huppertz, H. and Kaiser, P. and Liese, J. and Streng, A. and Niehues, T. and Peters, J. and Sauerbrey, A. and Schroten, H. and Tenenbaum, T. and Wirth, S. and Wutzler, P.}, title = {Prevalence of antibodies against influenza A and B viruses in children in Germany, 2008 to 2010}, series = {Eurosurveillance}, volume = {19}, journal = {Eurosurveillance}, number = {5}, issn = {1560-7917}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-117347}, pages = {20687}, year = {2014}, abstract = {The prevalence of influenza A and B virus-specific IgG was determined in sera taken between 2008 and 2010 from 1,665 children aged 0-17 years and 400 blood donors in Germany. ELISA on the basis of whole virus antigens was applied. Nearly all children aged nine years and older had antibodies against influenza A. In contrast, 40\% of children aged 0-4 years did not have any influenza A virus-specific IgG antibodies. Eighty-six percent of 0-6 year-olds, 47\% of 7-12 year-olds and 20\% of 13-17 year-olds were serologically naive to influenza B viruses. By the age of 18 years, influenza B seroprevalence reached approximately 90\%. There were obvious regional differences in the seroprevalence of influenza B in Germany. In conclusion, seroprevalences of influenza A and influenza B increase gradually during childhood. The majority of children older than eight years have basal immunity to influenza A, while comparable immunity against influenza B is only acquired at the age of 18 years. Children aged 0-6 years, showing an overall seroprevalence of 67\% for influenza A and of 14\% for influenza B, are especially at risk for primary infections during influenza B seasons.}, language = {en} }