@article{WalterGrussNeidlingeretal.2020,
  author    = {Walter, Steffen and Gruss, Sascha and Neidlinger, Jana and Stross, Isabelle and Hann, Alexander and Wagner, Martin and Seufferlein, Thomas and Walter, Benjamin},
  title     = {Evaluation of an Objective Measurement Tool for Stress Level Reduction by Individually Chosen Music During Colonoscopy—Results From the Study "ColoRelaxTone"},
  series = {Frontiers in Medicine},
  volume    = {7},
  journal   = {Frontiers in Medicine},
  doi       = {10.3389/fmed.2020.00525},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-212337},
  year      = {2020},
  abstract  = {Background and Aims: Colonoscopy as standard procedure in endoscopy is often perceived as uncomfortable for patients. Patient's anxiety is therefore a significant issue, which often lead to avoidance of participation of relevant examinations as CRC-screening. Non-pharmacological anxiety management interventions such as music might contribute to relaxation in the phase prior and during endoscopy. Although music's anxiolytic effects have been reported previously, no objective measurement of stress level reduction has been reported yet. Focus of this study was to evaluate the objective measurement of the state of relaxation in patients undergoing colonoscopy. Methods: Prospective study (n = 196) performed at one endoscopic high-volume center. Standard colonoscopy was performed in control group. Interventional group received additionally self-chosen music over earphones. Facial Electromyography (fEMG) activity was obtained. Clinician Satisfaction with Sedation Instrument (CSSI) and Patients Satisfaction with Sedation Instrument (PSSI) was answered by colonoscopists and patients, respectively. Overall satisfaction with music accompanied colonoscopy was obtained if applicable. Results: Mean difference measured by fEMG via musculus zygomaticus major indicated a significantly lower stress level in the music group [7.700(±5.560) μV vs. 4.820(±3.330) μV; p = 0.001]. Clinician satisfaction was significantly higher with patients listening to music [82.69(±15.04) vs. 87.3(±15.02) pts.; p = 0.001]. Patient's satisfaction was higher but did not differ significantly. Conclusions: We conclude that self-chosen music contributes objectively to a reduced stress level for patients and therefore subjectively perceived satisfaction for endoscopists. Therefore, music should be considered as a non-pharmacological treatment method of distress reduction especially in the beginning of endoscopic procedures.},
  language  = {en}
}
@article{HannGrafSeufferleinetal.2020,
  author    = {Hann, Alexander and Graf, Louisa and Seufferlein, Thomas and Zizer, Eugen},
  title     = {Gastrointestinal Bleeding Diagnosed by Capsule Endoscopy - A Change towards More Patients with Bleeding-related Drugs},
  series = {Journal of Advances in Medicine and Medical Research},
  volume    = {32},
  journal   = {Journal of Advances in Medicine and Medical Research},
  number    = {19},
  issn      = {2456-8899},
  doi       = {10.9734/JAMMR/2020/v32i1930662},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-256687},
  year      = {2020},
  abstract  = {Background: Video capsule endoscopy (VCE) is the standard procedure for a work-up of a suspected bleeding source after negative gastroscopy and colonoscopy. Popularity of this procedure increased in the last decade. In this work we aimed to identify the changes in patient characteristics and how those changes influence bleeding related findings. In particular the assumed higher risk of gastrointestinal bleeding of the new oral anticoagulants (nOAC) compared to phenprocoumon was of interest. Methods: Consecutive VCE examinations performed at our center from January 2004 to March 2018 were identified retrospectively. Baseline characteristics of the patients, VCE results and treatment that was initiated were analyzed. Results: 560 VCE were included in the analysis. The rate of VCE per month increased from 2.3/month in the period of January 2004 - December 2012 up to 5.0/month in January 2013 - March 2018. Accompanied by this increase the examined patients suffered from significantly more comorbidities (72 vs. 82\%, p 0.001) and used a higher number of bleeding-related drugs (47 vs. 66\%, p <0.001), especially nOACs. Age above 65 and bleeding-related drugs were significantly associated with angiodysplasias found on VCE examinations. NOACs and phenprocoumon showed no difference in their correlation to angiodysplasias. Conclusion: This single center retrospective analysis revealed a steep increase in VCE examinations over the last years with an increase in the prevalence of comorbidities and the use of bleeding-related drugs. Interestingly, use of both nOACs and phenprocoumon did not result in a significant higher rate of angiodysplasias in the VCE.},
  language  = {en}
}