@article{HengelsbergTackeFritscheetal.1991,
  author    = {Hengelsberg, H. and Tacke, Reinhold and Fritsche, K. and Syldatk, C. and Wagner, F.},
  title     = {Synthesis and enantioselective enzymatic hydrolysis of rac-dimethylphenyl[1-(phenylacetamido)- ethyl]silane},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-64153},
  year      = {1991},
  abstract  = {Racemic dimethylphenyl(l-(phenylacetamido)ethyl)silane [rac-5) has been made by a four-step synthesis starting from (chloromethyl)dimethylphenylsilane [PhMe\(_2\)SiCH2Cl (1) ~ PhMe\(_2\)SiCH(Cl)Me (rac-2) - PhMe\(_2\)SiCH(l)Me (rac-3) - PhMe2SiCH(NH2)Me (rac-4) ~ PhMe\(_2\)SiCH[N(H)C(O)CH\(_2\)Ph]Me ( rac-5); total yield 41\% ). Enantioselective enzymatic hydrolysis of rac-5, catalyzed by immobilized penicillin G acylase (E.C. 3.5.1.11) from Escherichia coli 5K (pHM 12), gave (R)-(1- aminoethyl)dimethylphenylsilane [( R )-4] in 40\% yield with an enantiomeric purity of 92\% ee.},
  subject      = {Anorganische Chemie},
  language  = {en}
}
@article{FritscheSyldatkWagneretal.1989,
  author    = {Fritsche, K. and Syldatk, C. and Wagner, F. and Hengelsberg, H. and Tacke, Reinhold},
  title     = {Enzymatic resolution of rac-1,1-dimethyl-1-sila-cyclohexan-2-ol by ester hydrolysis or transesterification using a crude lipase preparation of Candida cylindracea},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63967},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Anorganische Chemie},
  language  = {en}
}
@article{SyldatkAndreeStoffregenetal.1987,
  author    = {Syldatk, C. and Andree, H. and Stoffregen, A. and Wagner, F. and Stumpf, B. and Ernst, L. and Zilch, H. and Tacke, Reinhold},
  title     = {Enantioselective reduction of acetyldimethylphenylsilane by Trigonopsis variabilis (DSM 70714)},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63836},
  year      = {1987},
  abstract  = {Growing and resting cells of the yeast Trigonapsis variabilis (DSM 70714) can be used for the enantioselective reduction of the organosilicon compound acetyldimethylphenylsilane (J) to give optically active (R)-(1-hydroxyethyl)dimethylphenylsilane [(R)-2] in good yields. The enantiomeric purity of the isolated product was determined tobe 62-86\% ee depending on the substrate concentration used. Both substrate and product caused an inhibition of the reaction at concentrations higher than 0.35 and 0.5 g/1, respectively. Besides, higher substrate and product concentrations led to increased formation of the by-product 1,1,3,3-tetramethyl-1,3-diphenyldisiloxane. Considering the limiting substrate and product concentrations, it was possible to use the same biomass at least 5 times without significant loss of enzyme activity. 3-Methyl-3-phenyl-2-butanone (5) and acetyldimethylphenylgermane (7), which represent carbon and germanium analogues of 1, were also found to be accepted as substrates by Trigonapsis variabilis (DSM 70714). The reduction rates of the silicon {1) and germanium compound {7) were much higher than the transformation rate of the corresponding carbon analogue 5.},
  subject      = {Anorganische Chemie},
  language  = {en}
}