@article{TackeWiesenberger1991, author = {Tacke, Reinhold and Wiesenberger, Frank}, title = {(Acetoxymethyl)methylphenylgerman: Synthese, thermisches Verhalten und olfaktorische Eigenschaften}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86927}, year = {1991}, abstract = {No abstract available.}, subject = {Chemische Synthese}, language = {de} } @article{TackeWiesenbergerLopezMrasetal.1992, author = {Tacke, Reinhold and Wiesenberger, Frank and Lopez-Mras, Angel and Sperlich, J{\"o}rg and Mattern, G{\"u}nter}, title = {Neuartige zwitterionische λ5-Spirosilicate: Synthese und Kristallstruktur von Bis[1,2-benzoldiolato(2-)][2-(dimethylammonio)phenyl]silicat sowie Synthese von Bis[2,3-naphthalindiolato(2-)][2-(dimethylammonio)phenyl]silicat-Hemiacetonitril-Solvat}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86916}, year = {1992}, abstract = {No abstract available.}, subject = {Silicate}, language = {de} } @article{TackeKropfgansTafeletal.1994, author = {Tacke, Reinhold and Kropfgans, Martin and Tafel, Andrea and Wiesenberger, Frank and Sheldrick, William S. and Mutschler, Ernst and Egerer, Hansj{\"o}rg and Rettenmayr, Nikola and Gross, Jan and Waelbroeck, Magali and Lambrecht, G{\"u}nter}, title = {(Hydroxymethyl)diphenyl(piperidinoalkyl)silane des Typs (HOCH2)(C6H5)2Si(CH2)nNC5H10 (n = 2,3) und deren Methoiodide: Synthese, Struktur und antimuscarinische Eigenschaften}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86904}, year = {1994}, abstract = {No abstract available.}, language = {de} } @article{TackeHallerZeiler1979, author = {Tacke, Reinhold and Haller, Ingo and Zeiler, Hans-Joachim}, title = {Sila-Analoga der Antiseptica Octafoniumchlorid und p-tert-Butylphenol}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86893}, year = {1979}, abstract = {No abstract available.}, subject = {Silaanaloga}, language = {de} } @article{TackeSperlichStrohmannetal.1992, author = {Tacke, Reinhold and Sperlich, J{\"o}rg and Strohmann, Carsten and Frank, Brigitta and Mattern, G{\"u}nter}, title = {Bis[3,4,5,6-tetrabrom-1,2-benzoldiolato(2-)]-(pyrrolidiniomethyl)silicat-Acetonitril-Solvat [(C6Br4O2)2SiCH2(H)NC4H8 · CH3CN]: Synthese sowie Kristall- und Molek{\"u}lstruktur eines zwitterionischen [lambda]5-Spirosilicats}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86884}, year = {1992}, abstract = {Single crystal X-ray studies on bis[3,4,5,6-tetrabromo-1 ,2-benzenediolato(2- )](pyrrolidiniomethyl)silicate acetonitrile solvate [(C6Br40 2hSiCH2(H)NC4H8 · CH3CN; monoclinic, P2t/c, a = 808.5(4), b = 1533.0(8), c = 2212.6(1) pm, ß = 97.67(2)0 , Z = 4] revealed a zwitterionic structure with a pentacoordinate, formally negatively charged silicon atom and a positively charged ammonium moiety. The silicon atom is surrounded by four oxygen atoms and one carbon atom in a trigonalbipyramidal fashion, with the carbon atom in an equatorial position. The structure is displaced by 7.0\% from the trigonal bipyramid towards the square pyramid. The zwitterion and the CH3CN molecule form intermolecular N-H · · · N hydrogen bonds.}, subject = {Kristallstruktur}, language = {de} } @article{EpeHaeringRamaiahetal.1993, author = {Epe, Bernd and H{\"a}ring, Martin and Ramaiah, Danaboyina and Stopper, Helga and Abou-Elzahab, Mohamed M. and Adam, Waldemar and Saha-M{\"o}ller, Chantu R.}, title = {DNA damage induced by furocoumarin hydroperoxides plus UV (360 nm)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86870}, year = {1993}, abstract = {Wben irradiated at 360 nm, furocoumarins with a hydroperoxide group in a side chain effciently give rise to a type of DNA damage that can best be explained by a photoinduced generation of hydroxyl radicals from the excited pbotosensitizers. The observed DNA damage profiles, i.e. the ratios of single-strand breaks, sites of base loss (AP sites) and base modifications sensitive to fonnamidopyrimidine-DNA glycosylase (FPG protein) and endonuclease m, are similar to the DNA damage profile produced by hydroxyl radicals generated by lonizing radiation or by xanthine and xanthine oxidase in the presence of Fe(III)-EDTA. No such damage is observed with the corresponding furocoumarin alcohols or in the absence of near-UV radiation. The damage caused by the photo-excited hydroperoxides is not influenced by superoxide dismutase (SOD) or catalase or by D2O as solvent. The presence of t-butanol, however, reduces both the formation of single-strand breaks and of base odifications sensitive to FPG protein. The cytotoxicity caused by one of the hydroperoxides in L5178Y mome lymphoma cells is found to be dependent on the near-UV irradiation and to be much higher than that of the corresponding alcohol. Therefore the new type of photoinduced damage occurs inside cells. Intercalating photosensitizers with an attached hydroperoxide group might represent a novel and versatile class of DNA damaging agents, e.g. for phototherapy.}, subject = {DNS-Sch{\"a}digung}, language = {en} } @article{ZimmermannStopper1986, author = {Zimmermann, U. and Stopper, Helga}, title = {Elektrofusion und Elektropermeabilisierung von Zellen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86865}, year = {1986}, abstract = {No abstract available.}, subject = {Elektrofusion}, language = {de} } @article{JanevskiChohStopperetal.1993, author = {Janevski, J. and Choh, V. and Stopper, Helga and Schiffmann, D. and De Boni, U.}, title = {Diethylstilbestrol alters the morphology and calcium levels of growth cones of PC12 cells in vitro}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86858}, year = {1993}, abstract = {Diethylstilbestrol (DES) is a synthetic estrogen with carcinogenic properties. DES is known to alter cytoskeletal components, including the organization of actin stress fibres in C6 rat glioma cells. ln a test of the hypothesis that DES disrupts actin Filaments of growth cones in neuron-like cells, DES-induced changes in filopodial lengths were quantified in rat pheochromocytoma (PC12) cells in vitro. DES significantly altered growth cone morphology, with collapse of growth cone filopodia and neurite retraction invariably occurring at a concentration of 10 MikroM. At 5 MikroM DES, transient reductions in total filopodiallengths occurred. At DES concentrations of 0.1 nM and 1 nM, reductions in total filopodiallengths occurred in a fraction of growth cones. Evidence exists which shows that growth cone activity and morphology are intimately linked to Ieveis of intracellular, free calcium and that DES increases such levels. Measurements of free intracellular calcium levels by fluorescence microscopy, at times concurrent with the DES-induced reduction in total filopodial lengths, showed that calcium levels were indeed significantly increased by 10 MirkoM DES. Labelling of filamentaus actin (f-actin) with FITC-phalloidin showed that the f-actin distribution in growth cones exposed to DES could not be differentiated from the distribution found in spontaneously retracting growth cones. Tagether with evidence which showed that growth cone motility was not affected, the results are taken to indicate that DES, rather than acting directly on the cytoskeleton, exerts its effects indirectly, by a calcium-induced destabilization of actin filaments in the growth cone.}, subject = {Calcium}, language = {en} } @article{Sponholz1990, author = {Sponholz, Barbara}, title = {Silicate karst in eastern Niger - a geomorphological study}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86846}, year = {1990}, abstract = {No abstract available.}, subject = {Niger }, language = {en} } @article{Sponholz1994, author = {Sponholz, Barbara}, title = {Ph{\´e}nom{\´e}nes karstiques dans les roches siliceuses au Niger oriental}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86833}, year = {1994}, abstract = {Dans le Niger oriental, des ph{\´e}nomenes karstiques sont fr{\´e}quents dans les roches siliceuses: gres, silcretes, cro{\^u}tes ferrugineuses, roches cristallines. A partir des {\´e}tudes g{\´e}omorphologiques et micromorphologiques, on peut conclure a une kartsification, au sense de production de formes par dissolution. Les r{\´e}sultats permettent de dater du Tertiaire inf{\´e}rieur la principale p{\´e}riode de karstification. La r{\´e}partition r{\´e}gionale des formes induites par cette karstification indique une d{\´e}pendance probable des conditions pal{\´e}oclimatiques. Actuellement le karst influe encore sur le d{\´e}veloppement des autres formes de relief.}, language = {fr} }