@phdthesis{Peng2020,
  author    = {Peng, Kun},
  title     = {iClick reactions as a modular access to palladium(II) and platinum(II) triazolato complexes: Trends in kinetics and biological activity},
  doi       = {10.25972/OPUS-21161},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-211613},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2020},
  abstract  = {In the context of this work, important trends in the influence of the metal center, coligand, and alkyne reaction partner on the iClick reaction of square-planar palladium(II) and platinum(II) complexes with a N^N^N, C^N^N, or S^N^N coordination sphere and a number of internal as well as terminal alkynes were elaborated. Preliminary bioactivity studies on a human cancer cell line gave low micromolar EC50 values, for the most promising compound comparable to cisplatin serving as a reference drug. The further application of the iClick reaction to bioconjugation will be explored in future work.},
  subject      = {Click-Chemie},
  language  = {en}
}