@article{GrundmeierHammWeissbrichetal.2012,
  author    = {Grundmeier, Natalie and Hamm, Henning and Weissbrich, Benedikt and Lang, Sabrina Christine and Br{\"o}cker, Eva-Bettina and Kerstan, Andreas},
  title     = {High-risk human papillomavirus infection in Bowen's disease of the nail unit: report of three cases and review of the literature},
  series = {Dermatology},
  volume    = {223},
  journal   = {Dermatology},
  number    = {4},
  issn      = {1018-8665},
  doi       = {10.1159/000335371},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-196638},
  pages     = {293 -- 300},
  year      = {2012},
  abstract  = {Background: Bowen's disease (BD) of the nail unit is associated with human papillomavirus (HPV) infection. Objective: This study aimed to investigate the frequency of high-risk HPV infection, gender, age and digital distribution in this condition. Methods: Biopsy specimens of 3 consecutive cases with periungual BD were investigated for the presence of HPV DNA by in situ hybridization and by polymerase chain reaction (PCR). Furthermore, 74 cases of ungual BD conducted with HPV genotyping as reported in the literature were reviewed. Results: PCR of biopsy specimens revealed in 2 cases infection with HPV-16 and in 1 case with HPV-73. Additionally, in 1 HPV-16-positive case HPV-31/33 was detected by in situ hybridization. In line, review of the literature demonstrated a clear association of HPV-positive BD with high-risk HPV types. Interestingly, age at diagnosis was significantly lower in women. Whereas in both genders the second to fourth fingers on both hands were commonly diseased, only in men the thumbs were also prominently affected. Conclusions: Infection with high-risk HPV types is common in BD of the nail unit suggesting the aetiological cause. Therefore, patients and partners should be closely followed up for digital and genital HPV-associated lesions.},
  language  = {en}
}
@article{BauerGoebelerWeissbrichetal.2015,
  author    = {Bauer, Boris and Goebeler, Matthias and Weissbrich, Benedikt and Kerstan, Andreas},
  title     = {Kerinokeratosis papulosa of childhood},
  series = {Dermatology},
  volume    = {231},
  journal   = {Dermatology},
  number    = {1},
  issn      = {1018-8665},
  doi       = {10.1159/000381539},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-198997},
  pages     = {1 -- 4},
  year      = {2015},
  abstract  = {Background: Kerinokeratosis papulosa (KP) is considered an extremely rare genodermatosis presenting usually as waxy papules on the trunk in childhood. Objective: To describe and analyze the clinical, histological and potential etiopathological aspects of KP. Methods: The dermatoscopic features of a new case of KP of childhood are investigated. The presence of human papillomavirus (HPV) DNA in lesional skin was studied by polymerase chain reaction. Furthermore, all cases of KP of childhood reported so far were reviewed. Results: As a diagnostic tool, we describe for the first time a dermatoscopic feature, namely a cribriform pattern of KP, in an 11-year-old boy. In addition, we detected HPV (type 57) in his KP lesions. Conclusions: Dermatoscopic examination might be a useful tool to distinguish KP from other skin lesions, e.g. common warts. The detection of HPV type 57 might hint to an etiological role of HPV for KP.},
  language  = {en}
}