@book{Hettrich2007,
  author    = {Hettrich, Heinrich},
  title     = {Materialien zu einer Kasussyntax des Ṛgveda},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-258943},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  pages     = {485},
  year      = {2007},
  abstract  = {Heinrich Hettrichs 2007 ver{\"o}ffentlichte "Materialien zu einer Kasussyntax des Ṛgveda" sind Vorarbeiten zu einer Kasussyntax der indogermanischen Grundsprache, die auf der Darstellung der wichtigsten und {\"a}ltesten Einzelsprachen aufbauen soll, zu denen auch das Vedische geh{\"o}rt. Die Datenbasis der Untersuchung ist der Rigveda mit einem Corpus von ca. 27.600 S{\"a}tzen. Die Untersuchung geht semasiologisch vor, fragt also nach den Bedeutungen der einzelnen morphologischen Kasus. In der vorliegenden Fassung finden sich ausf{\"u}hrliche Darstellungen zu den Kasus Lokativ, Ablativ und Dativ und zu den Konstruktionsmustern ausgew{\"a}hlter Verben.},
  language  = {de}
}
@incollection{Klein2007,
  author    = {Klein, Ralf},
  title     = {Der probabilistische Ansatz zur Modellierung des r{\"a}umlichen Einkaufsverhaltens},
  series = {Analysemethodik und Modellierung in der geographischen Handelsforschung},
  booktitle = {Analysemethodik und Modellierung in der geographischen Handelsforschung},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-185990},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  pages     = {55-73},
  year      = {2007},
  abstract  = {No abstract available.},
  language  = {de}
}
@book{OPUS4-18040,
  title     = {Analysemethodik und Modellierung in der geographischen Handelsforschung},
  editor    = {Klein, Ralf and Rauh, J{\"u}rgen},
  publisher = {L.I.S. Verlag},
  address   = {Passau},
  isbn      = {978-3-932820-32-8},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-180402},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  pages     = {153},
  year      = {2007},
  abstract  = {Methoden und Techniken sind in der geographischen Handelsforschung gleichermaßen in der Grundlagenforschung, in der universit{\"a}renAusbildung, in der praktischen Anwendung und der Fortbildung von hoher Bedeutung. Der vorliegende Band vertieft einige bekannte methodische Aspekte, setzt aber auch neue Akzente hinsichtlich Analysemethodik und Modellierung. Die Beitr{\"a}ge in dem vorliegenden Band zeigen weitergehende M{\"o}glichkeiten auf, in der geographischen Handelsforschung und insbesondere der Praxis bedeutsame Fragestellungen methodisch fassen und behandeln zu k{\"o}nnen. Die Reihenfolge der Beitr{\"a}ge ist thematisch gegliedert. Die Thematik wird zun{\"a}chst eher allgemein orientiert vorgestellt und dann mittels einer bestimmten Fragestellung oder Untersuchung konkretisiert. So wird der umfassende Beitrag von K. E. Klein zum Einsatz geographischer Informationssysteme im Einzelhandel durch die Studie von J. Scharfenberger zu mikrogeographischen Routing- und Marktpotenzialanalysen erg{\"a}nzt. Die Modellierung und Prognose von Marktgebieten im Einzelhandel wird von R. Klein zun{\"a}chst allgemein diskutiert und durch die Untersuchungen von C. Kanh{\"a}usser vertieft. Die Beitr{\"a}ge von R. Hesse / A. Schmid sowie J. Rauh / T. Schenk / M. Fehler / F. Kl{\"u}gl / F. Puppe zeigen mit Simulationsmodellen und der r{\"a}umlichen Optimierung neue methodische Anwendungsm{\"o}glichkeiten auf, die geeignet sind, die in der Regel vorhandene Trennung zwischen der individualistischen und der strukturellen Perspektive aufzul{\"o}sen. Erstgenannte wird in der Regel z.B. bei der Untersuchung des Konsumentenverhaltens eingenommen, die Letztgenannte bei der (Standort-)Analyse der Angebotsseite.},
  subject      = {Handelsforschung},
  language  = {de}
}
@misc{Albert2007,
  type      = {Master Thesis},
  author    = {Albert, Sebastian},
  title     = {Frau und Kind in der \(Yconomica\) Konrads von Megenberg - Ein Beitrag zur Weltsicht des sp{\"a}ten Mittelalters},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-143513},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2007},
  abstract  = {Die {\"O}konomik Konrads von Megenberg geh{\"o}rt zu einer Literaturgattung der Antike und des Mittelalters, die sich in Anlehnung an Aristoteles' Oeconomica mit dem Haushalt besch{\"a}ftigt. Anhand zweier Traktate aus dem Kapitel {\"u}ber das nicht herrschaftliche Haus wird in dieser Arbeit Konrads Sicht auf die Ehe, die Familie und die Kindererziehung mentalit{\"a}ts- und alltagsgeschichtlich untersucht.},
  subject      = {Conradus <de Megenberg> <1309-1374> <Yconomica>},
  language  = {de}
}
@phdthesis{Felten2007,
  author    = {Felten, Ioanna Margarita},
  title     = {Raum und Religion im kaiserzeitlichen Griechenland - Die sakralen Landschaften der Argolis, Achaias und Arkadiens},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-126630},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2007},
  abstract  = {Besch{\"a}ftigt man sich mit der griechischen Religion, besch{\"a}ftigt man sich zwangsl{\"a}ufig auch mit der griechischen Polis. Denn sie war Tr{\"a}gerin der griechischen Religion. So sind die sich daraus ergebenden „sakralen Landschaften" im Sinne der Humangeographie bzw. Raumsoziologie eine Konstruktion von Raum und damit ein relationales System, das vielfachen Formen der Umgestaltung unterliegt. Denn Religion ist genauso wie der Raum nicht statisch konstruiert. Vielmehr beschreibt sie ein Spannungsfeld von Kontinuit{\"a}ten, Umdeutungen und Br{\"u}chen. wie sie sich besonders in Zeiten des Wandels offenbaren. Eine solche Phase bedeutete auch die Integration Griechenlands in das R{\"o}mische Reich. So galt das Hauptinteresse der Arbeit der Periode nach Oktavians Sieg bei Actium und der darauffolgenden Etablierung der Provinz Achaia 27 v. Chr. bis hin zu Caracallas constitutio Antoniniana. Der geographische Rahmen orientierte sich an den peloponnesischen Regionen Achaia, Argolis und Arkadien. Sie erm{\"o}glichten es, das r{\"o}mische Griechenland jenseits der immer wieder erw{\"a}hnten Orte Athen, Sparta und Korinth zu erfassen. Die Ergebnisse werden zusammen mit historischen Fakten, Siedlungsstrukturen und wirtschaftlichen Bedingungen in einem ersten, topographisch orientierten Abschnitt formuliert. Im zweiten Teil der Abhandlung steht dagegen eine gesonderte Untersuchung {\"u}bergreifender Ph{\"a}nomene und ihre Einbindung in einen weitergefaßten geographischen Kontext im Vordergrund.},
  subject      = {Argolis},
  language  = {de}
}
@incollection{Ruhe2007,
  author    = {Ruhe, Ernstpeter},
  title     = {L'invention d'un proph{\`e}te: le livre de Sydrac},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-102413},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2007},
  abstract  = {No abstract available.},
  subject      = {Sidrac <Altfranz{\"o}sisch>},
  language  = {fr}
}
@article{Ruhe2007,
  author    = {Ruhe, Ernstpeter},
  title     = {Faire gondoler Proust : l'art du l{\´e}ger trembl{\´e} de Jean-Philippe Toussaint},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-102017},
  year      = {2007},
  abstract  = {No abstract available.},
  subject      = {Romanistik},
  language  = {fr}
}
@phdthesis{Neveling2007,
  author    = {Neveling, Kornelia},
  title     = {Molecular causes and consequences of genetic instability with respect to the FA/BRCA Caretaker Pathway},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-27383},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2007},
  abstract  = {In the context of this thesis, I investigated the molecular causes and functional consequences of genetic instability using a human inherited disease, Fanconi anemia. FA patients display a highly variable clinical phenotype, including congenital abnormalities, progressive bone marrow failure and a high cancer risk. The FA cellular phenotype is characterized by spontaneous and inducible chromosomal instability, and a typical S/G2 phase arrest after exposure to DNA-damaging agents. So far, 13 genes have been identified, whose biallelic (or, in the case of X-linked FANCB, hemizygous) mutations cause this multisystem disorder. The FA proteins interact in a multiprotein network, instrumental and essential in the cellular response to DNA damage. A more comprehensive summary of Fanconi anemia and its myriad clinical, cellular and molecular manifestations is provided in the introduction section of this thesis. The results of my experimental work are presented as published papers and manuscripts ready to be submitted. In the first publication, I investigated the connection between FA genes and bladder tumors. The question I tried to answer was whether a disruption of the FA/BRCA pathway may be a frequent and possibly causal event in bladder cancer, explaining the hypersensitivity of these cells to DNA-crosslinking agents. On the basis of my experimental data I arrived at the conclusion that disruption of the FA/BRCA pathway might be detrimental rather than advantageous for the majority tumor types by rendering them vulnerable towards DNA damaging agents and oxidative stress. The second publication deals with the gene coding for the core complex protein FANCE and tries to answer the question why FANCE is so rarely affected among FA-patients. The conclusion from these studies is that like FANCF, FANCE functions as a probable adaptor protein with a high tolerance towards amino acid substitutions which would explain the relative rareness of FA-E patients. I have also investigated the FANCL gene whose product functions as the catalytic subunit of the E3 ligase. The third publication addresses this issue by providing the first comprehensive description of genetic alterations and phenotypic manifestations in a series of three FA-L patients. The results of my study show that genetic alterations of FANCL are compatible with survival, these alterations may include large deletions such as so far common only in the FANCA gene, FA-L phenotypes can be mild to severe, and FANCL belongs to the group of FA genes that may undergo somatic reversion. The central protein of the FA/BRCA network, FANCD2, is the subject of the fourth publication presented in this thesis. Most importantly, we were able to show that there are no biallelic null mutations in FANCD2. Correspondingly, residual protein of both FANCD2-isotypes (FANCD2-S and FANCD2-L) was present in all available patient cell lines. This suggests that complete abrogation of the FANCD2 protein cannot be tolerated and causes early embryonic lethality. There are at least three FA proteins that are not required for the posttranslational modification of FANCD2. One of these proteins is the 5'-3' helicase BRIP1 (BRCA1-interacting protein 1), a protein that interacts directly with the breast cancer susceptibility protein BRCA1. I participated in the identification of BRIP1 as the FA protein FANCJ. This discovery is described in the fifth publication of this thesis. The newly discovered protein BRIP1/FANCJ seems to act as one of the mediators of genomic maintenance downstream of FANCD2. Another protein identified downstream of FANCD2 is PALB2. PALB2 was originally discovered as "partner and localizer of BRCA2". In a candidate gene approach we tested patients with early childhood cancers but without mutations in BRCA2 for mutations in PALB2 (publication 6). PALB2 was identified as a novel FA gene and designated FANCN. FA-N patients are very severely affected. The last publication included in my thesis describes the identification of the FA gene FANCI as the second monoubiquitinated member of the FA/BRCA pathway (publication 7). We identified biallelic mutations in KIAA1794 in four FA patients, thus proving the genuine FA-nature of this candidate sequence. The general discussion provides a synopsis of the results and conclusions of my work with the state of art of FA research.},
  subject      = {Fanconi-An{\"a}mie},
  language  = {en}
}
@article{HeisswolfUlmannObermaieretal.2007,
  author    = {Heisswolf, Annette and Ulmann, Sandra and Obermaier, Elisabeth and Mitesser, Oliver and Poethke, Hans J.},
  title     = {Host plant finding in the specialised leaf beetle Cassida canaliculata: an analysis of small-scale movement behaviour},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49485},
  year      = {2007},
  abstract  = {1. Host plant finding in walking herbivorous beetles is still poorly understood. Analysis of small-scale movement patterns under semi-natural conditions can be a useful tool to detect behavioural responses towards host plant cues. 2. In this study, the small-scale movement behaviour of the monophagous leaf beetle Cassida canaliculata Laich. (Coleoptera: Chrysomelidae) was studied in a semi-natural arena (r = 1 m). In three different settings, a host (Salvia pratensis L., Lamiales: Lamiaceae), a non-host (Rumex conglomeratus Murr., Caryophyllales: Polygonaceae), or no plant was presented in the centre of the arena. 3. The beetles showed no differences in the absolute movement variables, straightness and mean walking speed, between the three settings. However, the relative movement variables, mean distance to the centre and mean angular deviation from walking straight to the centre, were significantly smaller when a host plant was offered. Likewise, the angular deviation from walking straight to the centre tended to decline with decreasing distance from the centre. Finally, significantly more beetles were found on the host than on the non-host at the end of all the trials. 4. It is concluded that C. canaliculata is able to recognise its host plant from a distance. Whether olfactory or visual cues (or a combination of both) are used to find the host plant remains to be elucidated by further studies.},
  subject      = {K{\"a}fer},
  language  = {en}
}
@article{HeisswolfGablerObermaieretal.2007,
  author    = {Heisswolf, Annette and Gabler, Dirk and Obermaier, Elisabeth and M{\"u}ller, Caroline},
  title     = {Olfactory versus contact cues in host plant recognition of a monophagous chrysomelid beetle},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49475},
  year      = {2007},
  abstract  = {The importance of olfactory versus contact cues for host plant recognition was investigated in the tortoise beetle Cassida canaliculata Laich. (Coleoptera: Chrysomelidae), which is strictly monophagous on meadow sage. The reaction of adult beetles to olfactory and contact host cues was tested using three bioassays (locomotion compensator, six-chamber-olfactometer, stem arena') to account for different behavioral contexts. Bioassay-guided fractionation of plant extracts was elaborated to characterize the nature of contact stimuli. The beetles were only slightly attracted to odors from small amounts of leaf material. However, when contact cues were provided additionally, the beetles showed strong preferences for samples of their host plant over controls. Bioassay-guided fractionation led to isolation of at least two non-polar contact stimuli acting in concert that are sufficient for host plant identification in C. canaliculata.},
  subject      = {Insekt},
  language  = {en}
}