@article{DiloksumpandeRuijterCastilhoetal.2020,
  author    = {Diloksumpan, Paweena and de Ruijter, Myl{\`e}ne and Castilho, Miguel and Gbureck, Uwe and Vermonden, Tina and van Weeren, P Ren{\´e} and Malda, Jos and Levato, Riccardo},
  title     = {Combining multi-scale 3D printing technologies to engineer reinforced hydrogel-ceramic interfaces},
  series = {Biofabrication},
  volume    = {12},
  journal   = {Biofabrication},
  number    = {2},
  doi       = {10.1088/1758-5090/ab69d9},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-254005},
  year      = {2020},
  abstract  = {Multi-material 3D printing technologies that resolve features at different lengths down to the microscale open new avenues for regenerative medicine, particularly in the engineering of tissue interfaces. Herein, extrusion printing of a bone-biomimetic ceramic ink and melt electrowriting (MEW) of spatially organized polymeric microfibres are integrated for the biofabrication of an osteochondral plug, with a mechanically reinforced bone-to-cartilage interface. A printable physiological temperature-setting bioceramic, based on α-tricalcium phosphate, nanohydroxyapatite and a custom-synthesized biodegradable and crosslinkable poloxamer, was developed as bone support. The mild setting reaction of the bone ink enabled us to print directly within melt electrowritten polycaprolactone meshes, preserving their micro-architecture. Ceramic-integrated MEW meshes protruded into the cartilage region of the composite plug, and were embedded with mechanically soft gelatin-based hydrogels, laden with articular cartilage chondroprogenitor cells. Such interlocking design enhanced the hydrogel-to-ceramic adhesion strength >6.5-fold, compared with non-interlocking fibre architectures, enabling structural stability during handling and surgical implantation in osteochondral defects ex vivo. Furthermore, the MEW meshes endowed the chondral compartment with compressive properties approaching those of native cartilage (20-fold reinforcement versus pristine hydrogel). The osteal and chondral compartment supported osteogenesis and cartilage matrix deposition in vitro, and the neo-synthesized cartilage matrix further contributed to the mechanical reinforcement at the ceramic-hydrogel interface. This multi-material, multi-scale 3D printing approach provides a promising strategy for engineering advanced composite constructs for the regeneration of musculoskeletal and connective tissue interfaces.},
  language  = {en}
}
@article{SchmitterBoemickeBehnischetal.2022,
  author    = {Schmitter, Marc and B{\"o}micke, Wolfgang and Behnisch, Rouven and Lorenzo Bermejo, Justo and Waldecker, Moritz and Rammelsberg, Peter and Ohlmann, Brigitte},
  title     = {Ceramic crowns and sleep bruxism: first results from a randomized trial},
  series = {Journal of Clinical Medicine},
  volume    = {12},
  journal   = {Journal of Clinical Medicine},
  number    = {1},
  issn      = {2077-0383},
  doi       = {10.3390/jcm12010273},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-301480},
  year      = {2022},
  abstract  = {Background: This randomized clinical trial was conducted to assess whether sleep bruxism (SB) is associated with an increased rate of technical complications (ceramic defects) in lithium disilicate (LiDi) or zirconia (Z) molar single crowns (SCs). Methods: Adult patients were classified as affected or unaffected by SB based on structured questionnaires, clinical signs, and overnight portable electromyography (BruxOff) and block randomized into four groups according to SB status and crown material (LiDi or Z): LiDi-SB (n = 29), LiDi-no SB (n = 24), Z-SB (n = 23), and Z-no SB (n = 27). Differences in technical complications (main outcome) and survival and success rates (secondary outcomes) one year after crown cementation were assessed using Fisher's exact test with significance level α = 0.05. Results: No technical complications occurred. Restoration survival rates were 100\% in the LiDi-SB and LiDi-no SB groups, 95.7\% in the Z-SB group, and 96.3\% in the Z-no SB group (p > 0.999). Success rates were 96.6\% in the LiDi-SB group, 95.8\% in the LiDi-no SB group (p > 0.999), 91.3\% in the Z-SB group, and 96.3\% in the Z-no SB group (p ≥ 0.588). Conclusions: With a limited observation time and sample size, no effect of SB on technical complication, survival, and success rates of molar LiDi and Z SCs was detected.},
  language  = {en}
}
@phdthesis{Kelmendi2022,
  author    = {Kelmendi, Arsim},
  title     = {Aush{\"a}rtung von Kompositen bei Belichtung durch unterschiedliche Schichtst{\"a}rken von Keramik},
  doi       = {10.25972/OPUS-26978},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-269789},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2022},
  abstract  = {{\"A}sthetische Restaurationsverfahren sind in den meisten Zahnarztpraxen mittlerweile Routine. Zielsetzung: Diese Studie ging der Frage nach, inwieweit die Aush{\"a}rtung von Kompositen unter Keramikrestaurationen m{\"o}glich ist. Material und Methoden: Anhand von 426 mit Tetric Ceram® und 102 mit Variolink® hergestellten Proben wurden folgende Abh{\"a}ngigkeiten ber{\"u}cksichtigt: Lichtger{\"a}t und Belichtungsdauer, Schichtst{\"a}rke und Farbe der Keramik, H{\"a}rtemodus des Composits - im vorliegenden Fall ob lichth{\"a}rtendes oder dualh{\"a}rtendes Composit - und schließlich beim dualh{\"a}rtenden Composit, der Einfluss einer kurzen Wartezeit zwischen Anmischen der Paste und Lichtpolymerisation. Diskussion: Um eine ausreichende Aush{\"a}rtung und gute Haftfestigkeit von lichth{\"a}rtenden Befestigungscomposites unter keramischen Restaurationen zu gew{\"a}hrleisten, ist eine ungehinderte Belichtung mit einem Polymerisationslicht f{\"u}r mindestens 25 Sekunden erforderlich, vorzugsweise aus sechs Richtungen, insbesondere dann, wenn die Keramik dunkler eingef{\"a}rbt ist. Bei der Bestrahlung von Keramikschichten mit einer Wandst{\"a}rke ≥ 2 mm werden dualh{\"a}rtende Komposite und l{\"a}ngere Belichtungszeiten empfohlen.},
  subject      = {Komposit Keramik},
  language  = {de}
}