@article{LohseKlotzUkenaetal.1984, author = {Lohse, M. J. and Klotz, K.-N. and Ukena, D. and Schwabe, U.}, title = {Characterization of \([^3H]\)Phenobarbital Binding to Rat Brain Membranes}, series = {Neuroscience Letters}, volume = {52}, journal = {Neuroscience Letters}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-127894}, pages = {97-101}, year = {1984}, abstract = {The binding of \([^3H]\)phenobarbital to rat brain membranes was studied in order to determine its characteristics and specificity. The binding reaction was rapid and occurred at sites of low affinity. \((K_d = 700 μM)\) and very high density \((B_{max} = 2.7 nmoll/mg protein)\). It was unaffected by temperature changes from O°C to 95°C and was maximal at pH 5. Detergents in low concentrations markedly decreased the binding, apparently without solubilizing the binding sites. It is concluded that the binding of \([^3H]\) phenobarbital is a rather non-specific interaction with the plasma membrane.}, language = {en} } @article{WilhelmFranke1984, author = {Wilhelm, Gernot and Franke, Sabina}, title = {Eine mittelassyrische fiktive Urkunde zur Wahrung des Anspruchs auf ein Findelkind}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-107265}, year = {1984}, abstract = {no Abstract available}, subject = {Findelkind}, language = {de} } @article{SebaldArendsMcCarthy1984, author = {Sebald, Walter and Arends, Hermann and McCarthy, John E. G.}, title = {Isolation and manipulation of genes coding for energy-transducing enzymes from Neurospora crassa and Escherichia coli}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86768}, year = {1984}, abstract = {No abstract available.}, subject = {Escherichia coli}, language = {en} } @inproceedings{AndersSchartlBarnekow1984, author = {Anders, Fritz and Schartl, Manfred and Barnekow, Angelika}, title = {Xiphophorus as an in vivo model for studies on oncogenes}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86398}, year = {1984}, abstract = {The capacity of Xiphophorus to develop neoplasia can be formally assigned to a "tumor gene" (Tu), which appears to be a normal part of the genome of all individuals. The wild fish have evolved population-specific and cell type-specific systems of regulatory genes (R) for Tu that protect the fish from neoplasia. Hybridization of members of different wild populations in the laborstory followed by treatment of the hybrids with carcinogens led to disintegration of the R systems permitting excessive expression of Tu and thus resulting in neoplasia. Certain hybrids developed neoplasia even spontaneously. Observations on the genuine phenotypic effect of the derepressed Tu in the early embryo indicated an essential normal function of this oncogene in cell differentiation, proliferation and cell-cell communication. Tu appeared to be indispensable in the genome but may also be present in accessory copics. Recently, c-src, the cellular homolog of the Rous sarcoma virus oncogene v-src, was detected in Xiphophorus. The protein product of c-src, pp60c-src, was identified and then examined by its associated kinase activity. This pp60c-src was found in all individuals tested, but, depending on the genotype, its kinase activity was different. The genetic characters of c-src, such as linkage relations, dosage relations, expression, etc., correspond to those of Tu. From a systematic study which showed that pp60c-src was present in all metazoa tested ranging from mammals down to sponges, we concluded that c-src has evolved with the multicellular organization of animals. Neoplasia of animals and humans is a characteristic closely related to this evolution. Our data showed that small aquariurn fish, besides being used successfully because they are time-, space-, and money-saving systems for carcinogenicity testing, are also highly suitable for basic studies on neoplasia at the populational, morphological, developmental, cell biological, and molecular levels.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @article{MeyerSchartl1984, author = {Meyer, Manfred K. and Schartl, Manfred}, title = {Pseudotropheus (Maylandia) hajomaylandi n. sp., a new taxon from Lake Malawi}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-70989}, year = {1984}, abstract = {Pseudotropheus hajomaylandi (loc. typ. Isle of Chisumulu, Lake Malawi) is described as a new species. It is compared with Ps. aurora, Ps. greshakei, Ps. livingstonii, Ps. lombardoi, and Ps. zebra. All these taxa, including Ps. hajomaylandi and Ps. heteropictus, are classified in the subgenus Maylandia.}, subject = {Buntbarsche}, language = {en} } @article{Wilhelm1984, author = {Wilhelm, Gernot}, title = {Hurritisch nari(ya) "f{\"u}nf"}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-85784}, year = {1984}, abstract = {no Abstract available}, subject = {Minoische Kultur}, language = {de} } @article{Wilhelm1984, author = {Wilhelm, Gernot}, title = {Die Inschrift auf der Statue der Tatu-ḫepa und die hurritischen deiktischen Pronomina}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-85779}, year = {1984}, abstract = {no Abstract available}, subject = {Minoische Kultur}, language = {de} } @article{Wilhelm1984, author = {Wilhelm, Gernot}, title = {Zur Pal{\"a}ographie der in {\"A}gypten geschriebenen Keilschriftbriefe}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-70371}, year = {1984}, abstract = {no Abstract available}, subject = {{\"A}gypten }, language = {de} } @article{HoppeSebald1984, author = {Hoppe, J. and Sebald, Walter}, title = {The proton conducting F0-part of bacterial ATP synthases}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-82019}, year = {1984}, abstract = {No abstract available}, subject = {Biologie}, language = {en} } @article{Schneider1984, author = {Schneider, Wolfgang}, title = {Zur Entwicklung des Metaged{\"a}chtnisses bei Kindern}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-81004}, year = {1984}, abstract = {Neuere Untersuchungen zeigen, daß f{\"u}r die unterschiedlichen Ged{\"a}chtnisleistungen bei Kindern nicht verschieden große Ged{\"a}chtniskapazit{\"a}ten verantwortlich sind. Vielmehr k{\"o}nnen manche Kinder die zum Lernen und Erinnern n{\"o}tigen Strategien nicht effektiv genug einsetzen ; sie wissen zu wenig {\"u}ber ihr Ged{\"a}chtnis. Eine F{\"o}rderung dieses Ged{\"a}chtniswissens k{\"o}nnte ihre schulischen Leistungen erheblich verbessern.}, subject = {Metaged{\"a}chtnis}, language = {de} }