@article{KrzymanskiWaagaUlrichsetal.1991, author = {Krzymanski, Maciej and Waaga, Ana M. and Ulrichs, Karin and Deja, Aadam and Oko, Andrzej and Rommel, Thomas and M{\"u}ller-Ruchholtz, Wolfgang}, title = {The influence of MHC class II antigen blockade by perfusion with a monoclonal antibody on rat renal graft survival}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-64431}, year = {1991}, abstract = {To decrease immunogenicity of the rat kidney, grafts were perfused with an anti-MHC class li monoclonal antibody (mAb ). How effectively this procedure blocked dass li-positive cells, which were mainly dendritic in appearance, was checked by immunostaining renal sections after perfusion and comparing them with in vitro stained sections. Optimum conditions were applied for graft pretreatment before transplantation. This procedure prolonged graft survival, though not satisfactorily from the biological point ofview (9.6 ± 0.8 versus 7.7 ± 0.5 days in the control group; P < 0.02). The dendritic cells were not killed but blocked. Several hours after transplantation, the mAb dissociated from these dass li-positive cells. It was also shown that donor cells migrate into the recipient's spieen early after transplantation. The number of these cells was smaller when the transplanted organ was perfused with the mAb. Further studies are suggested to deplete the graft of donor dendritic cells more adequately. They should also combine graft perfusion with antidass II mAb and recipient immunosuppression at reduced doses.}, subject = {Chirurgie}, language = {en} } @article{UlrichsWinotoMorbachHeringetal.1990, author = {Ulrichs, Karin and Winoto-Morbach, S. and Hering, B. and M{\"u}ller-Ruchholtz, W.}, title = {A Useful Biotechnological Approach to Solve the Problem of Graft Purity in Human Pancreatic Islet Transplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45619}, year = {1990}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsMuellerRuchholtz1985, author = {Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Further Analyses of Pancreas Islet Immunogenicity, a Major Barrier to Successful Islet Transplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45563}, year = {1985}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsMuellerRuchholtz1988, author = {Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Expression of MHC Structures on Immunologically Reactive and Non Reactive Cells in Islets of Langerhans and Other Tissues}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45557}, year = {1988}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{WaagaUlrichsKrzymanskietal.1990, author = {Waaga, AM and Ulrichs, Karin and Krzymanski, M. and Treumer, J. and Hansmann, ML and Rommel, T. and M{\"u}ller-Ruchholz, W.}, title = {The immunosuppressive agent 15-deoxyspergualin induces tolerance and modulates MHC-antigen expression and interleukin-1 production in the early phase of rat allograft responses}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45253}, year = {1990}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsEcksteinMuellerBuchholtz1994, author = {Ulrichs, Karin and Eckstein, V. and M{\"u}ller-Buchholtz, W.}, title = {Xenogeneic T-cell-mediated immune reactivity in the model of pig-to-humans: first findings with native stimulator cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44755}, year = {1994}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsBosseWackeretal.1994, author = {Ulrichs, Karin and Bosse, M. and Wacker, HH and Heiser, A. and M{\"u}ller-Ruchholtz, W.}, title = {Histologic analysis of the porcine pancreas to improve islet yield and integrity after collagenase digestion}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45166}, year = {1994}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{HeiserUlrichsMuellerRuchholtz1994, author = {Heiser, A. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Influence of porcine strain, age, and pH of the isolation medium on porcine pancreatic islet isolation success}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45171}, year = {1994}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{WinotoMorbachKroutHeiseretal.1994, author = {Winoto-Morbach, S. and Krout, OS and Heiser, A. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Lectin binding to acinar tissue for complete magnetophoretic purification of porcine pancreatic islets depends on the composition and pH of the incubation medium}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45183}, year = {1994}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsWangMuellerBuchholtz1994, author = {Ulrichs, Karin and Wang, H. and M{\"u}ller-Buchholtz, W.}, title = {Down-regulation of xenophile antibodies by 15-deoxyspergualin in an experimental animal model}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44733}, year = {1994}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} }