@techreport{Gross2022,
  author    = {Groß, Lennart},
  title     = {Advices derived from troubleshooting a sensor-based adaptive optics direct stochastic optical reconstruction microscope},
  doi       = {10.25972/OPUS-28995},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-289951},
  pages     = {20},
  year      = {2022},
  abstract  = {One rarely finds practical guidelines for the implementation of complex optical setups. Here, we aim to provide technical details on the decision making of building and revising a custom sensor-based adaptive optics (AO) direct stochastic optical reconstruction microscope (dSTORM) to provide practical assistance in setting up or troubleshooting similar devices. The foundation of this report is an instrument constructed as part of a master's thesis in 2021, which was built for deep tissue imaging. The setup is presented in the following way: (1) An optical and mechanical overview of the system at the beginning of this internship is given. (2) The optical components are described in detail in the order at which the light passes through, highlighting their working principle and implementation in the system. The optical component include (2A) a focus on even sample illumination, (2B) restoring telecentricity when working with commercial microscope bodies, (2C) the AO elements, namely the deformable mirror (DM) and the wavefront sensor, and their integration, and (2D) the separation of wavefront and image capture using fluorescent beads and a dichroic mirror. After addressing the limitations of the existing setup, modification options are derived. The modifications include the implementation of adjustment only light paths to improve system stability and revise the degrees of freedom of the components and changes in lens choices to meet the specifications of the AO components. Last, the capabilities of the modified setup are presented and discussed: (1) First, we enable epifluorescence imaging of bead samples through 180 µm unstained murine hippocampal tissue with wavefront error correction of ~ 90 \%. Point spread function, wavefront shape and Zernike decomposition of bead samples are presented. (2) Second, we move from epifluorescent to dSTORM imaging of tubulin stained primary mouse hippocampal cells, which are imaged through up to 180 µm of unstained murine hippocampal tissue. We show that full width at half maximum (FWHM) of prominent features can be reduced in size by nearly a magnitude from uncorrected epiflourescence images to dSTORM images corrected by the adaptive optics. We present dSTORM localization count and FWHM of prominent features as as a function of imaging depth.},
  subject      = {Einzelmolek{\"u}lmikroskopie},
  language  = {en}
}
@techreport{MeyerJobLaneretal.2022,
  author    = {Meyer, Constantin and Job, Hubert and Laner, Peter and Omizzolo, Andrea and Kollmann, Nadia and Clare, Jasmin and Vesely, Philipp and Riedler, Walter and Plassmann, Guido and Coronado, Oriana and Praper Gulič, Sergeja and Gulič, Andrej and Koblar, Simon and Teofili, Corrado and Rohringer, Verena and Schoßleitner, Richard and Ainz, Gerhard},
  title     = {OpenSpaceAlps Planning Handbook: Perspectives for consistent safeguarding of open spaces in the Alpine region},
  doi       = {10.25972/OPUS-27040},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-270401},
  pages     = {110},
  year      = {2022},
  abstract  = {In the Alpine region, the continuous consumption of open spaces for settlement areas and technical infrastructure and the associated soil sealing can be observed. This leads primarily to the loss of agricultural land. Depending on the extent of development, there is also increased landscape fragmentation, which is associated with the isolation of natural habitats and the restriction of ecological connectivity, as well as other negative consequences. The OpenSpaceAlps project has addressed this issue and, based on cooperative procedures in several pilot regions, has developed approaches and solution strategies for the sustainable safeguarding of open spaces. This handbook supports the activities and decision-making of various stakeholders, first and foremost planners in public planning authorities. Based on an analysis of the challenges and framework conditions in the Alpine region, the handbook presents and compares central "principles" of open space planning. Furthermore, integrated planning strategies for different spatial categories are discussed.},
  subject      = {Raumordnung},
  language  = {en}
}
@techreport{NordPetzke2023,
  author    = {Nord, Ilona and Petzke, Judith},
  title     = {Religious Education in the digital change. Concepts and reflections from a German context},
  edition   = {revised version},
  doi       = {10.25972/OPUS-32858},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-328582},
  pages     = {30},
  year      = {2023},
  abstract  = {The article presents results from the project Religious Education Laboratory digital (RELab digital): At a time when exclusive access to religion in the classroom seems less and less plausible, the concept of digital religion education we propose leads back to the existential needs for religion. It can refer to the thematic fields of digital religions, which in turn are not new for religious education, but remix its traditions and themes in the mirror of transforming communication cultures: authority, community, truth, communication, autonomy, religion, identity, and ritual. Chapter 1 contains a description of the project structure. Chapter 2 is dedicated to the pedagogical challenge of teaching Religious Education (RE) in the digital change. Chapter 3 reflects from a pedagogical standpoint on empirical findings of the project, which were developed in the context of classroom observations and interviews. Chapter 4 focuses on topics related to the profession of teachers: What self-concepts are pursued by teachers of Religious Education and/or can be reconstructed through the way they act in the classroom? How can the often critical perceptions of teachers who use digital media in religious education be put to good use in the future? The conclusion bundles the most important insights and highlights examples of further research.},
  subject      = {Digitalisierung},
  language  = {en}
}
@techreport{BoeschStielerLydonetal.2023,
  author    = {B{\"o}sch, Carolin and Stieler, Malena and Lydon, Salomon and Hesse, Martin and Ali, Hassan and Finzel, Matthias and Faraz Ali, Syed and Salian, Yash and Alnoor, Hiba and John, Jeena and Lakkad, Harsh and Bhosale, Devraj and Jafarian, Timon and Parvathi, Uma and Ezzatpoor, Narges and Datar, Tanuja},
  title     = {Venus Research Station},
  issn      = {2747-9374},
  doi       = {10.25972/OPUS-32869},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-328695},
  pages     = {232},
  year      = {2023},
  abstract  = {Because of the extreme conditions in the atmosphere, Venus has been less explored than for example Mars. Only a few probes have been able to survive on the surface for very short periods in the past and have sent data. The atmosphere is also far from being fully explored. It could even be that building blocks of life can be found in more moderate layers of the planet's atmosphere. It can therefore be assumed that the planet Venus will increasingly become a focus of exploration. One way to collect significantly more data in situ is to build and operate an atmospheric research station over an extended period of time. This could carry out measurements at different positions and at different times and thus significantly expand our knowledge of the planet. In this work, the design of a Venus Research Station floating within the Venusian atmosphere is presented, which is complemented by the design of deployable atmospheric Scouts. The design of these components is done on a conceptual basis.},
  subject      = {Venus},
  language  = {en}
}
@techreport{BofingerGeissendoerferHaasetal.2023,
  author    = {Bofinger, Peter and Geißend{\"o}rfer, Lisa and Haas, Thomas and Mayer, Fabian},
  title     = {Credit as an Instrument for Growth: A Monetary Explanation of the Chinese Growth Story},
  doi       = {10.25972/OPUS-32880},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-328804},
  pages     = {148},
  year      = {2023},
  abstract  = {This study describes the Chinese growth model over the past 40 years. We show that China's growth model, with its dominant role of the banking system and "the banker", is a perfect illustration of the necessity and power of Schumpeter's "monetary analysis". This approach has allowed us to elaborate theoretically and empirically the uniqueness of the Chinese model. In our empirical analysis, we use a new dataset of Chinese provincial data to analyze the impact of the financial system, especially banks, on Chinese economic development. We also empirically assess the role of the financial system in Chinese industrial policy and provide case studies of the effects of industrial policy in specific sectors. Finally, we also discuss macroeconomic dimensions of the Chinese growth process and lessons that can be drawn from the Chinese experience for other countries.},
  subject      = {Industriepolitik},
  language  = {en}
}
@techreport{NordPetzke2023,
  author    = {Nord, Ilona and Petzke, Judith},
  title     = {Religious Education in the digital change. Concepts and reflections from a German context},
  doi       = {10.25972/OPUS-32280},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-322802},
  pages     = {30},
  year      = {2023},
  abstract  = {The article presents results from the project Religious Education Laboratory digital (RELab digital): At a time when exclusive access to religion in the classroom seems less and less plausible, the concept of digital religion education we propose leads back to the existential needs for religion. It can refer to the thematic fields of digital religions, which in turn are not new for religious education, but remix its traditions and themes in the mirror of transforming communication cultures: authority, community, truth, communication, autonomy, religion, identity, and ritual. Chapter 1 contains a description of the project structure. Chapter 2 is dedicated to the pedagogical challenge of teaching Religious Education (RE) in the digital change. Chapter 3 reflects from a pedagogical standpoint on empirical findings of the project, which were developed in the context of classroom observations and interviews. Chapter 4 focuses on topics related to the profession of teachers: What self-concepts are pursued by teachers of Religious Education and/or can be reconstructed through the way they act in the classroom? How can the often critical perceptions of teachers who use digital media in religious education be put to good use in the future? The conclusion bundles the most important insights and highlights examples of further research.},
  subject      = {Digitalisierung},
  language  = {en}
}
@techreport{OPUS4-35963,
  title     = {Platelets - Molecular, cellular and systemic functions in health and disease},
  editor    = {Nieswandt, Bernhard},
  organization    = {Collaborative Research Centre/Transregio 240},
  doi       = {10.25972/OPUS-35963},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-359636},
  pages     = {25},
  year      = {2024},
  abstract  = {Besides their central role in haemostasis and thrombosis, platelets are increasingly recognised as versatile effector cells in inflammation, the innate and adaptive immune response, extracellular matrix reorganisation and fibrosis, maintenance of barrier and organ integrity, and host response to pathogens. These platelet functions, referred to as thrombo-inflammation and immunothrombosis, have gained major attention in the COVID-19 pandemic, where patients develop an inflammatory disease state with severe and life-threatening thromboembolic complications. In the CRC/TR 240, a highly interdisciplinary team of basic, translational and clinical scientists explored these emerging roles of platelets with the aim to develop novel treatment concepts for cardiovascular disorders and beyond. We have i) unravelled mechanisms leading to life-threatening thromboembolic complica-tions following vaccination against SARS-CoV-2 with adenoviral vector-based vaccines, ii) identified unrecognised functions of platelet receptors and their regulation, offering new potential targets for pharmacological intervention and iii) developed new methodology to study the biology of megakar-yocytes (MKs), the precursor cells of platelets in the bone marrow, which lay the foundation for the modulation of platelet biogenesis and function. The projects of the CRC/TR 240 built on the unique expertise of our research network and focussed on the following complementary fields: (A) Cell bi-ology of megakaryocytes and platelets and (B) Platelets as regulators and effectors in disease. To achieve this aim, we followed a comprehensive approach starting out from in vitro systems and animal models to clinical research with large prospective patient cohorts and data-/biobanking. Despite the comparably short funding period the CRC/TR 240 discovered basic new mechanisms of platelet biogenesis, signal transduction and effector function and identified potential MK/platelet-specific molecular targets for diagnosis and therapy of thrombotic, haemorrhagic and thrombo-inflammatory disease states.},
  subject      = {Thrombozyt},
  language  = {en}
}