@phdthesis{RamirezPasos2019,
  author    = {Ramirez Pasos, Uri Eduardo},
  title     = {Subthalamic Nucleus Neural Synchronization and Connectivity during Limbic Processing of Emotional Pictures: Evidence from Invasive Recordings in Patients with Parkinson's Disease},
  doi       = {10.25972/OPUS-16985},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-169850},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2019},
  abstract  = {In addition to bradykinesia and tremor, patients with Parkinson's disease (PD) are known to exhibit non-motor symptoms such as apathy and hypomimia but also impulsivity in response to dopaminergic replacement therapy. Moreover, a plethora of studies observe differences in electrocortical and autonomic responses to both visual and acoustic affective stimuli in PD subjects compared to healthy controls. This suggests that the basal ganglia (BG), as well as the hyperdirect pathway and BG thalamocortical circuits, are involved in affective processing. Recent studies have shown valence and dopamine-dependent changes in synchronization in the subthalamic nucleus (STN) in PD patients during affective tasks. This thesis investigates the role of dopamine, valence, and laterality in STN electrophysiology by analyzing event-related potentials (ERP), synchronization, and inter-hemispheric STN connectivity. STN recordings were obtained from PD patients with chronically implanted electrodes for deep brain stimulation during a passive affective picture presentation task. The STN exhibited valence-dependent ERP latencies and lateralized 'high beta' (28-40 Hz) event-related desynchronization. This thesis also examines the role of dopamine, valence, and laterality on STN functional connectivity with the anterior cingulate cortex (ACC) and the amygdala. The activity of these limbic structures was reconstructed using simultaneously recorded electroencephalographic signals. While the STN was found to establish early coupling with both structures, STN-ACC coupling in the 'alpha' range (7-11 Hz) and uncoupling in the 'low beta' range (14-21 Hz) were lateralized. Lateralization was also observed at the level of synchrony in both reconstructed sources and for ACC ERP amplitude, whereas dopamine modulated ERP latency in the amygdala. These results may deepen our current understanding of the STN as a limbic node within larger emotional-motor networks in the brain.
},
  subject      = {Nucleus subthalamicus},
  language  = {en}
}
@article{ThierschmannArnoldMittermuelleretal.2015,
  author    = {Thierschmann, H and Arnold, F and Mitterm{\"u}ller, M and Maier, L and Heyn, C and Hansen, W and Buhmann, H and Molenkamp, L W},
  title     = {Thermal gating of charge currents with Coulomb coupled quantum dots},
  series = {New Journal of Physics},
  volume    = {17},
  journal   = {New Journal of Physics},
  number    = {113003},
  doi       = {10.1088/1367-2630/17/11/113003},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-145196},
  year      = {2015},
  abstract  = {We have observed thermal gating, i.e. electrostatic gating induced by hot electrons. The effect occurs in a device consisting of two capacitively coupled quantum dots. The double dot system is coupled to a hot electron reservoir on one side (QD1), while the conductance of the second dot (QD2) is monitored. When a bias across QD2 is applied we observe a current which is strongly dependent on the temperature of the heat reservoir. This current can be either enhanced or suppressed, depending on the relative energetic alignment of the QD levels. Thus, the system can be used to control a charge current by hot electrons.},
  language  = {en}
}
@article{KasprzakSivalertpornAlbertetal.2013,
  author    = {Kasprzak, J. and Sivalertporn, K. and Albert, F. and Schneider, C. and H{\"o}fling, S. and Kamp, M. and Forchel, A. and Muljarov, E. A. and Langbein, W.},
  title     = {Coherence dynamics and quantum-to-classical crossover in an exciton-cavity system in the quantum strong coupling regime},
  series = {New Journal of Physics},
  volume    = {15},
  journal   = {New Journal of Physics},
  number    = {045013},
  issn      = {1367-2630},
  doi       = {10.1088/1367-2630/15/4/045013},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-123005},
  year      = {2013},
  abstract  = {Interaction between light and matter generates optical nonlinearities, which are particularly pronounced in the quantum strong coupling regime. When a single bosonic mode couples to a single fermionic mode, a Jaynes-Cummings (JC) ladder is formed, which we realize here using cavity photons and quantum dot excitons. We measure and model the coherent anharmonic response of this strongly coupled exciton-cavity system at resonance. Injecting two photons into the cavity, we demonstrate a \(\sqrt 2\) larger polariton splitting with respect to the vacuum Rabi splitting. This is achieved using coherent nonlinear spectroscopy, specifically four-wave mixing, where the coherence between the ground state and the first (second) rung of the JC ladder can be interrogated for positive (negative) delays. With increasing excitation intensity and thus rising average number of injected photons, we observe spectral signatures of the quantum-to-classical crossover of the strong coupling regime.},
  language  = {en}
}