@article{BarnekowSchartlAndersetal.1982, author = {Barnekow, A. and Schartl, Manfred and Anders, F. and Bauer, H.}, title = {Identification of a fish protein associated with a kinase activity and related to the Rous sarcoma virus transforming protein}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61946}, year = {1982}, abstract = {No abstract available}, subject = {Physiologische Chemie}, language = {en} } @article{BergerHackerJuarezetal.1982, author = {Berger, Harald and Hacker, J{\"o}rg and Juarez, Antonio and Hughes, Colin and Goebel, Werner}, title = {Cloning of the chromosomal determinants encoding hemolysin production and mannose-resistant hemagglutination in Escherichia coli}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-40255}, year = {1982}, abstract = {We have cloned the chromosomal hemolysin determinants from Escherichia coli strains belonging to the four O-serotypes 04, 06, 018, and 075, The hemolysin-producing clones were isolated from gene banks of these strains which were constructed by inserting partial Sau3A fragments of chromosomal DNA into the cosmid pJC74. The hemolytic cosmid clones were relatively stable. The inserts were further sub cloned either as Sail fragments in pACYC184 or as BamHI-SaLI fragments in a recombinant plasmid (pANN202) containing cistron C (hlye) of the plasmid-encoded hemolysin determinant. Detailed restriction maps of each of these determinants were constructed, and it was found that, despite sharing overall homology, the determinants exhibited minor specific differences in their structure, These appeared to be restricted to cistron A (hlyA), which is the structural gene for hemolysin. In the gene banks of two of these hemolytic strains, we could also identify clones which carried the genetic determinants for the mannose-resistant hemagglutination antigens Vb and VIc. Both of these fimbrial antigens were expressed in the E. coli K-12 clones to an extent similar to that observed in the wild-type strains. These recombinant cosmids were rather unstable, and, in the absence of selection, segregated at a high frequency.}, language = {en} } @article{ChristlLang1982, author = {Christl, Manfred and Lang, R.}, title = {Tricyclo[5.1.0.0\(^{2,8}\)]octa-3,5-diene (Octavalene)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58124}, year = {1982}, abstract = {No abstract available}, subject = {Organische Chemie}, language = {en} } @article{HofEmmerlingHackeretal.1982, author = {Hof, H. and Emmerling, P. and Hacker, J{\"o}rg and Hughes, C.}, title = {The role of macrophages in primary and secondary infection of mice with Salmonella typhimurium}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-40248}, year = {1982}, abstract = {Elimination of macrophages with high-molecular dextran sulphate (OS) markedly impairs resistance of mice to primary infection with smooth, virulent strains of Salmonella typhimurium, whereas stimulation of this system by killed Bordetella pertussis organisms increases resistance. In infection with rough, avirulent strains of S. iyphimurium the elimination of macro phages was not followed by an essential loss of resistance, and it appears that other non-specific defence mechanisms, for example the complement system, may have compensated for the lack of macrophages. Macrophages, therefore, play an important role in defence during primary infection with virulent strains. In immunity to challenge infection with S. typhimurium, macrophages play an even more significant role. Treatment with OS completely removes immunity, and both humoral and cell-mediated immune mechanisms seem to require the participation of macrophages.}, language = {en} } @article{HughesMuellerHackeretal.1982, author = {Hughes, Colin and M{\"u}ller, Dorothee and Hacker, J{\"o}rg and Goebel, Werner}, title = {Genetics and pathogenic role of Escherichia coli hemolysin}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-40082}, year = {1982}, abstract = {While clear evidence exists for the direct involvement of cytolysins in the pathogenesis of Gram-positive bacteria, the significance of Gram-negative haemolysins remains unclear. This paper presents briefly data indicating a role for haemolysin production in infections caused by Escherichia coli and also experiments which have allowed an analysis of the molecular basis of the haemolysis among pathogenic and non-pathogenic strains of this species.}, language = {en} } @article{KohnenKrueger1982, author = {Kohnen, Ralf and Kr{\"u}ger, Hans-Peter}, title = {Tranquillizer effects in an experimental analog of verbal examinations}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41617}, year = {1982}, abstract = {In an experimental analog of verbal examinations, the call-up situation, the effects of two dosages of a tranquillizing agent (lopirazepam) are compared to placebo treatment. 72 male and female, healthy, young volunteers have been randomly assigned to 12 groups of 6 subjects each. Pulse frequency and performance were registered. The results indicated differential drug effects which were interpreted according to the hypotheses of "differential effects of social stressors". If a situation was highly challenging for a subject, the application of a tranquillizer in an adequately high dosage enabled him to perform well in spite of or because of strong increases in pulse frequency.}, language = {en} } @article{KreftHughes1982, author = {Kreft, J{\"u}rgen and Hughes, Colin}, title = {Cloning vectors derived from plasmids and phage of Bacillus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47014}, year = {1982}, abstract = {No abstract available}, language = {en} } @article{KruegerKohnen1982, author = {Kr{\"u}ger, Hans-Peter and Kohnen, Ralf}, title = {Tranquillizer effects in an experimental analog of group psychotherapy}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41316}, year = {1982}, abstract = {In an experimental analog of verbal examinations, the call-up situation, the effects of two dosages of a tranquillizing agent (lopirazepam) are compared to placebo treatment. 72 male and female, healthy, young volunteers have been randomly assigned to 12 groups of 6 subjects each. Pulse frequency and performance were registered. The results indicated differential drug effects which were interpreted according to the hypotheses of "differential effects of social stressors". If a situation was highly challenging for a subject, the application of a tranquillizer in an adequately high dosage enabled him to perform well in spite of or because of strong increases in pulse frequency.}, language = {en} } @article{KuehnBurschkaWerner1982, author = {Kuehn, A. and Burschka, Christian and Werner, H.}, title = {Synthesis and molecular structure of C\(_5\)H\(_5\)(P-/-Pr\(_3\))Pd(η\(^1\), η\(^3\)-C\(_3\)H\(_4\))Pd(P-/-Pr\(_3\))Br: a compound formed through insertion of allene into a metal-metal bond\(^1\)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46592}, year = {1982}, abstract = {No abstract available}, subject = {Chemie}, language = {en} } @article{LutzJaggiSchlatter1982, author = {Lutz, Werner K. and Jaggi, W. and Schlatter, C.}, title = {Covalent binding of diethylstilbestrol to DNA in rat and hamster liver and kidney [Short Communication]}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61066}, year = {1982}, abstract = {No abstract available}, subject = {Toxikologie}, language = {en} }