@article{SchwitterWackerWilkeetal.2012, author = {Schwitter, Juerg and Wacker, Christian M. and Wilke, Norbert and Al-Saadi, Nidal and Sauer, Ekkehart and Huettle, Kalman and Sch{\"o}nberg, Stefan O. and Debl, Kurt and Strohm, Oliver and Ahlstrom, Hakan and Dill, Thorsten and Hoebel, Nadja and Simor, Tamas}, title = {Superior diagnostic performance of perfusion-cardiovascular magnetic resonance versus SPECT to detect coronary artery disease: The secondary endpoints of the multicenter multivendor MR-IMPACT II (Magnetic Resonance Imaging for Myocardial Perfusion Assessment in Coronary Artery Disease Trial)}, series = {Journal of Cardiovascular Magnetic Resonance}, volume = {14}, journal = {Journal of Cardiovascular Magnetic Resonance}, number = {61}, organization = {MR-IMPACT investigators}, doi = {10.1186/1532-429X-14-61}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-134256}, year = {2012}, abstract = {Background: Perfusion-cardiovascular magnetic resonance (CMR) is generally accepted as an alternative to SPECT to assess myocardial ischemia non-invasively. However its performance vs gated-SPECT and in sub-populations is not fully established. The goal was to compare in a multicenter setting the diagnostic performance of perfusion-CMR and gated-SPECT for the detection of CAD in various populations using conventional x-ray coronary angiography (CXA) as the standard of reference. Methods: In 33 centers (in US and Europe) 533 patients, eligible for CXA or SPECT, were enrolled in this multivendor trial. SPECT and CXA were performed within 4 weeks before or after CMR in all patients. Prevalence of CAD in the sample was 49\% and 515 patients received MR contrast medium. Drop-out rates for CMR and SPECT were 5.6\% and 3.7\%, respectively (ns). The study was powered for the primary endpoint of non-inferiority of CMR vs SPECT for both, sensitivity and specificity for the detection of CAD (using a single-threshold reading), the results for the primary endpoint were reported elsewhere. In this article secondary endpoints are presented, i.e. the diagnostic performance of CMR versus SPECT in subpopulations such as multi-vessel disease (MVD), in men, in women, and in patients without prior myocardial infarction (MI). For diagnostic performance assessment the area under the receiver-operator-characteristics-curve (AUC) was calculated. Readers were blinded versus clinical data, CXA, and imaging results. Results: The diagnostic performance (= area under ROC = AUC) of CMR was superior to SPECT (p = 0.0004, n = 425) and to gated-SPECT (p = 0.018, n = 253). CMR performed better than SPECT in MVD (p = 0.003 vs all SPECT, p = 0.04 vs gated-SPECT), in men (p = 0.004, n = 313) and in women (p = 0.03, n = 112) as well as in the non-infarct patients (p = 0.005, n = 186 in 1-3 vessel disease and p = 0.015, n = 140 in MVD). Conclusion: In this large multicenter, multivendor study the diagnostic performance of perfusion-CMR to detect CAD was superior to perfusion SPECT in the entire population and in sub-groups. Perfusion-CMR can be recommended as an alternative for SPECT imaging.}, language = {en} } @techreport{Segueda2015, type = {Working Paper}, author = {Segueda, Wendpanga Eric}, title = {Imported Religions, Colonialism and the Situation of Women in Africa}, edition = {1}, issn = {2199-4315}, doi = {10.25972/OPUS-12240}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-122400}, pages = {24}, year = {2015}, abstract = {Women are a key to development, and gender is crucial to development policies. However, Western development organisations often promote gender equality as something valued in the West, or even as a new idea altogether, rather than taking the time to research how it was rooted in African societies. The same holds true for many Africans who frequently argue that gender equality is a Western idea. This paper intents to show that gender equality or complementarity is not an altogether new phenomenon to African societies, but that it existed in pre-colonial Africa. Raising awareness on this within African societies can help to put in place strategies for gender equality and facilitate change from within.}, subject = {Afrika}, language = {en} } @article{SchmiemannGreserMaunetal.2023, author = {Schmiemann, Guido and Greser, Alexandra and Maun, Andy and Bleidorn, Jutta and Schuster, Angela and Miljukov, Olga and R{\"u}cker, Viktoria and Klingeberg, Anja and Mentzel, Anja and Minin, Vitalii and Eckmanns, Tim and Heintze, Christoph and Heuschmann, Peter and G{\´a}gyor, Ildik{\´o}}, title = {Effects of a multimodal intervention in primary care to reduce second line antibiotic prescriptions for urinary tract infections in women: parallel, cluster randomised, controlled trial}, series = {BMJ}, volume = {383}, journal = {BMJ}, issn = {1756-1833}, doi = {10.1136/bmj-2023-076305}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-349395}, year = {2023}, abstract = {Objectives To evaluate whether a multimodal intervention in general practice reduces the proportion of second line antibiotic prescriptions and the overall proportion of antibiotic prescriptions for uncomplicated urinary tract infections in women. Design Parallel, cluster randomised, controlled trial. Setting General practices in five regions in Germany. Data were collected between 1 April 2021 and 31 March 2022. Participants General practitioners from 128 randomly assigned practices. Interventions Multimodal intervention consisting of guideline recommendations for general practitioners and patients, provision of regional data for antibiotic resistance, and quarterly feedback, which included individual first line and second line proportions of antibiotic prescribing, benchmarking with regional or supra-regional practices, and telephone counselling. Participants in the control group received no information on the intervention. Main outcome measures Primary outcome was the proportion of second line antibiotics prescribed by general practices, in relation to all antibiotics prescribed, for uncomplicated urinary tract infections after one year between the intervention and control group. General practices were randomly assigned in blocks (1:1), with a block size of four, into the intervention or control group using SAS version 9.4; randomisation was stratified by region. The secondary outcome was the prescription proportion of all antibiotics, relative within all cases (instances of UTI diagnosis), for the treatment of urinary tract infections after one year between the groups. Adverse events were assessed as exploratory outcomes. Results 110 practices with full datasets identified 10 323 cases during five quarters (ie, 15 months). The mean proportion of second line antibiotics prescribed was 0.19 (standard deviation 0.20) in the intervention group and 0.35 (0.25) in the control group after 12 months. After adjustment for preintervention proportions, the mean difference was -0.13 (95\% confidence interval -0.21 to -0.06, P\<0.001). The overall proportion of all antibiotic prescriptions for urinary tract infections over 12 months was 0.74 (standard deviation 0.22) in the intervention and 0.80 (0.15) in the control group with a mean difference of -0.08 (95\% confidence interval -0.15 to -0.02, P\<0.029). No differences were noted in the number of complications (ie, pyelonephritis, admission to hospital, or fever) between the groups. Conclusions The multimodal intervention in general practice significantly reduced the proportion of second line antibiotics and all antibiotic prescriptions for uncomplicated urinary tract infections in women. Trial registration German Clinical Trials Register (DRKS), DRKS00020389}, language = {en} } @phdthesis{Eisenbarth2008, author = {Eisenbarth, Hedwig}, title = {Assessment of emotional detachment in psychopathy via self-report and an emotion detection task}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-27817}, school = {Universit{\"a}t W{\"u}rzburg}, year = {2008}, abstract = {The personality construct of psychopathy is subject of growing research, but data on psychopathy in female incarcerated and in non-institutionalized samples are rare. In this thesis emotional detachment as one factor of psychopathy is investigated in general population, in patients and in incarcerated samples. After verifying the validity of the Psychopathy Personality Inventory Revised (PPI-R) measuring emotional detachment, the sensitivity of the questionnaire concerning emotional detachment has been proven. Additionally it has been shown that symptoms of attention deficit and hyperactivity disorder can be distinguished from psychopathic traits by emotional detachment. In addition, these results confirm the core role of the feature emotional detachment for psychopathy. Furthermore, two emotion recognition tasks have been conducted in a criminal female inpatients sample. Compared to the low psychopathic patients, the high psychopathic patients showed deficits in categorization only in shortly presented sad facial expressions, but rated emotional facial expressions as less arousing. These results point to emotional detachment as a core characteristic of psychopathy, and is specific even in non-incarcerated and female incarcerated samples. It can be measured with the PPI-R as well as with emotion detection tasks.}, subject = {Psychopathie}, language = {en} } @article{Andres2013, author = {Andres, Katharina}, title = {'Fashion's Final Frontier': The Correlation of Gender Roles and Fashion in Star Trek}, series = {Culture Unbound}, volume = {5}, journal = {Culture Unbound}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-128827}, pages = {639-649}, year = {2013}, abstract = {Since its creation in 1966, Star Trek has been a dominant part of popular culture and as thus served as the source for many cultural references. Star Trek's creator Gene Roddenberry wanted to realize his vision of a utopia but at the same time, he used the futuristic setting of the show to comment on the present time, on actual social and political circumstances. This means that each series can be regarded as a mirror image of the time in which it was created. The clothing of the characters in the different series is one part of that image. The uniforms of The Original Se-ries show influences of the 1960s pop art movement as well as the mini-skirt trend that experienced its peak in that decade. In the course of almost 40 years, howev-er, many things changed. In the 1990s, in Deep Space Nine and Voyager, a unisex uniform replaced the mini-dresses, with few exceptions; the colorful shirts gave way to ones that were mostly black. This trend continues into the new century. This essay interprets the evolution of the female officers' uniforms from femi-nized dresses to androgynous clothing over the development of the series as a reflection of the change of gender roles in contemporary American society. The general functions of the female characters' uniforms are the central object of its analysis while the few, but noteworthy exceptions to this pattern are given specif-ic attention. Finally, one of the most intriguing lines of enquiry is, how the pre-quel series Enterprise, supposed to be set before The Original Series, but pro-duced and aired from 2001 to 2005, fits in the picture.}, language = {en} }