@article{MuellerKrennSchindleretal.1993, author = {M{\"u}ller, J. G. and Krenn, V. and Schindler, C. and Czub, S. and Stahl-Henning, C. and Coulibaly, C. and Hunsmann, G. and Kneitz, C. and Kerkau, T. and Rethwilm, A. and ter Meulen, V. and M{\"u}ller-Hermelink, H. K.}, title = {Alterations of Thymus Cortical Epithelium and Interdigitating Dendritic Cells but No Increase of Thymocyte Cell Death in the Early Course of Simian Immunodeficiency Virus Infection}, series = {American Journal of Pathology}, volume = {143}, journal = {American Journal of Pathology}, number = {3}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-128250}, pages = {699-713}, year = {1993}, abstract = {The role of the thymus in the pathogenesis of simian acquired immunodeficiency syndrome was investigated in 18 juvenile rhesus monkeys (Macaca mulatta). The thymus was infected from the first week post-SIVmac inoculation, but the amount of virus-positive cells was very low « 1 in 1 04 T cells) as demonstrated by polymerase chain reaction and in situ hybridization. First morphological alteration was a narrowing of the cortex at 12 and 24 wpi. Morphometry revealed no increase of pyknotic T cells but a decrease of the proliferation rate andflow cytometry showed a reduction of the immature \(CD4^+/CD8^+\) double-positive T cells. Ultrastructural analysis revealed vacuolization, shrinkage, andfinally cytolysis of the cortical epithelial cells and the interdigitating dendritic cells. Immunofluorescence staining exhibited a widespread loss of cortical epithelial cells. This damage to the thymic microenvironment could explain the breakdown of the intrathymic T cell proliferation. It preceded fully developed simian acquired immunodeficiency syndrome and is therefore considered to play a major role in its pathogenesis.}, language = {en} } @article{SchneiderSchauliesLiebertBaczkoetal.1988, author = {Schneider-Schaulies, Sibylle and Liebert, UG and Baczko, K, and ter Meulen, V.}, title = {Molecular Biological Analysis of Measles Virus Gene Expression in the CNS of Acutely and Persistently Infected Rat Brain Cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-81784}, year = {1988}, subject = {Virologie}, language = {en} } @article{SchneiderSchauliesLiebertBaczkoetal.1988, author = {Schneider-Schaulies, Sibylle and Liebert, UG and Baczko, K. and ter Meulen, V.}, title = {Molecular Biological Aspects of Virus-Induced Subacute Encephalomyelitis in Lewis Rats}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-81776}, year = {1988}, abstract = {no abstract available}, subject = {Biologie}, language = {en} } @article{SchneiderSchauliesSchneiderSchauliesSchusteretal.1994, author = {Schneider-Schaulies, Sibylle and Schneider-Schaulies, J{\"u}rgen and Schuster, A. and Bayer, M. and Pavlovic, J. and ter Meulen, V.}, title = {Cell type specific MxA-mediated inhibition of measles virus transcription in human brain cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62255}, year = {1994}, abstract = {No abstract available}, subject = {Virologie}, language = {en} } @article{SegevRagerZismanIsakovetal.1994, author = {Segev, Y. and Rager-Zisman, B. and Isakov, N. and Schneider-Schaulies, Sibylle and ter Meulen, V. and Udem, S. A. and Segal, S. and Wolfson, M.}, title = {Reversal of measles virus mediated increase of phosphorylating activity in persistently infected mouse neuroblastoma cells by anti measles antibodies}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62362}, year = {1994}, abstract = {No abstract available}, subject = {Virologie}, language = {en} } @article{SchnorrSchneiderSchauliesSimonJoedickeetal.1993, author = {Schnorr, J. J. and Schneider-Schaulies, Sibylle and Simon-J{\"o}dicke, A. and Pavlovic, J. and Horisberger, M. A. and ter Meulen, V.}, title = {MxA dependent inhibition of Measles Virus glycoprotein synthesis in a stably transfected human monocytic cell line}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62353}, year = {1993}, abstract = {No abstract available}, subject = {Virologie}, language = {en} } @article{SchneiderSchauliesLiebertRagerZismanetal.1992, author = {Schneider-Schaulies, Sibylle and Liebert, U. G. and Rager-Zisman, B. and Wolfson, M. and ter Meulen, V.}, title = {Antibody-dependent transcriptional regulation of measles virus in persistently infected neural cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62329}, year = {1992}, abstract = {No abstract available}, subject = {Virologie}, language = {en} } @article{SchneiderSchauliesKrethHofmannetal.1991, author = {Schneider-Schaulies, Sibylle and Kreth, H. W. and Hofmann, G. and Billeter, M. A. and ter Meulen, V.}, title = {Expression of measles virus RNA in peripheral blood mononuclear cells of patients with measles, SSPE, and autoimmune diseases}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62297}, year = {1991}, abstract = {No abstract available}, subject = {Virologie}, language = {en} } @article{SchneiderSchauliesLiebertBaczkoetal.1990, author = {Schneider-Schaulies, Sibylle and Liebert, U. G. and Baczko, K. and ter Meulen, V.}, title = {Restricted expression of measles virus in primary rat astroglial cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62283}, year = {1990}, abstract = {No abstract available}, subject = {Virologie}, language = {en} } @article{LiebertSchneiderSchauliesBaczkoetal.1990, author = {Liebert, U. G. and Schneider-Schaulies, Sibylle and Baczko, K. and ter Meulen, V.}, title = {Antibody-induced restriction of viral gene expression in measles encephalitis in rats}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62271}, year = {1990}, abstract = {No abstract available}, subject = {Virologie}, language = {en} }