@article{JansenOhlendorfErhardetal.2013,
  author    = {Jansen, Nils and Ohlendorf, Birgit and Erhard, Arlette and Bruhn, Torsten and Bringmann, Gerhard and Imhoff, Johannes F.},
  title     = {Helicusin E, Isochromophilone X and Isochromophilone XI: New Chloroazaphilones Produced by the Fungus Bartalinia robillardoides Strain LF550},
  series = {Marine Drugs},
  volume    = {11},
  journal   = {Marine Drugs},
  number    = {3},
  doi       = {10.3390/md11030800},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-129649},
  pages     = {800-816},
  year      = {2013},
  abstract  = {Microbial studies of the Mediterranean sponge Tethya aurantium led to the isolation of the fungus Bartalinia robillardoides strain LF550. The strain produced a number of secondary metabolites belonging to the chloroazaphilones. This is the first report on the isolation of chloroazaphilones of a fungal strain belonging to the genus Bartalinia. Besides some known compounds (helicusin A (1) and deacetylsclerotiorin (2)), three new chloroazaphilones (helicusin E (3); isochromophilone X (4) and isochromophilone XI (5)) and one new pentaketide (bartanolide (6)) were isolated. The structure elucidations were based on spectroscopic analyses. All isolated compounds revealed different biological activity spectra against a test panel of four bacteria: three fungi; two tumor cell lines and two enzymes.},
  language  = {en}
}