@article{FetschGaitzschMessageretal.2016,
  author    = {Fetsch, Corinna and Gaitzsch, Jens and Messager, Lea and Battaglia, Giuseppe and Luxenhofer, Roberts},
  title     = {Self-Assembly of Amphiphilic Block Copolypeptoids - Micelles, Worms and Polymersomes},
  series = {Scientific Reports},
  volume    = {6},
  journal   = {Scientific Reports},
  doi       = {10.1038/srep33491},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-147855},
  pages     = {33491},
  year      = {2016},
  abstract  = {Polypeptoids are an old but recently rediscovered polymer class with interesting synthetic, physico-chemical and biological characteristics. Here, we introduce new aromatic monomers, N-benzyl glycine N-carboxyanhydride and N-phenethyl glycine N-carboxyanhydride and their block copolymers with the hydrophilic polysarcosine. We compare their self-assembly in water and aqueous buffer with the self-assembly of amphiphilic block copolypeptoids with aliphatic side chains. The aggregates in water were investigated by dynamic light scattering and electron microscopy. We found a variety of morphologies, which were influenced by the polymer structure as well as by the preparation method. Overall, we found polymersomes, worm-like micelles and oligo-lamellar morphologies as well as some less defined aggregates of interconnected worms and vesicles. Such, this contribution may serve as a starting point for a more detailed investigation of the self-assembly behavior of the rich class of polypeptoids and for a better understanding between the differences in the aggregation behavior of non-uniform polypeptoids and uniform peptoids.},
  language  = {en}
}