@phdthesis{Gluyas2012,
  author    = {Gluyas, Josef Bheinn George},
  title     = {Synthesis of Silicon-Based Drugs and Odourants},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72182},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2012},
  abstract  = {This thesis concerns (i) the synthesis and olfactory characterisation of silicon-containing analogues of the musk odourant phantolide, (ii) the synthesis and pharmacological investigation of silicon-containing analogues of retinoids of the EC23 and TTNN type and (iii) the attempted syntheses of silicon-containing analogues of the antipsychotic penfluridol and the antidiarrhoeal agent loperamide. All target compounds and intermediates were characterised by multinuclear NMR studies (1H, 13C, 15N, 19F, 29Si) and elemental analyses or high-resolution mass spectrometry. Additionally, some of these compounds were characterized by single crystal X-ray diffraction studies.},
  subject      = {Silicium},
  language  = {en}
}
@phdthesis{Heinrich2004,
  author    = {Heinrich, Tilman},
  title     = {Siliciumorganische Wirkstoffe : Synthese und pharmakologische Eigenschaften siliciumhaltiger Muscarin-, Dopamin- und alpha1-Rezeptor-Antagonisten sowie Ca2+-Kanal-Blocker},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-11106},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2004},
  abstract  = {Im Rahmen der vorliegenden Arbeit wurden neuartige siliciumhaltige Muscarinrezeptor-Antagonisten, Dopaminrezeptor-Antagonisten, Ca2+-Kanal-Blocker sowie alpha1-Rezeptor-Antagonisten synthetisiert, welche Sila-Analoga (C/Si-Austausch) bekannter organischer Pharmaka darstellen. Die C/Si-Analoga wurden pharmakologisch charakterisiert und damit Beitr{\"a}ge zur Thematik der C/Si-Bioisosterie geleistet.},
  subject      = {Muscarinrezeptor},
  language  = {de}
}