@article{HolzapfelProdingerPilgeetal.2013, author = {Holzapfel, Boris Michael and Prodinger, Peter M. and Pilge, Hakan and Banke, Ingo J. and B{\"u}rklein, Dominik and Miethke, Thomas and Gradinger, Reiner}, title = {Acute Osteomyelitis of the Humerus mimicking Malignancy: Streptococcus pneumoniae as Exceptional Pathogen in an Immunocompetent Adult}, series = {BMC Infectious Diseases}, journal = {BMC Infectious Diseases}, doi = {10.1186/1471-2334-13-266}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-95790}, year = {2013}, abstract = {Background Chronic osteomyelitis due to direct bone trauma or vascular insufficiency is a frequent problem in orthopaedic surgery. In contrast, acute haematogenous osteomyelitis represents a rare entity that almost exclusively affects prepubescent children or immunodeficient adults. Case Presentation In this article, we report the case of acute pneumococcal osteomyelitis of the humerus in an immunocompetent and otherwise healthy 44-year-old male patient presenting with minor inflammation signs and misleading clinical features. Conclusions The diagnosis had to be confirmed by open biopsy which allowed the initiation of a targeted therapy. A case of pneumococcal osteomyelitis of a long bone, lacking predisposing factors or trauma, is unique in adults and has not been reported previously.}, language = {en} }