@article{UlrichsEulerSchroederetal.1992, author = {Ulrichs, Karin and Euler, HH and Schroeder, JO and M{\"u}ller-Ruchhholtz, W.}, title = {Long-term specific suppression of antibody production by plasmapheresis and a short-term course of cyclophosphamide}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45198}, year = {1992}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{BreitkreuzUlrichsEcksteinetal.1993, author = {Breitkreuz, A. and Ulrichs, Karin and Eckstein, V. and M{\"u}ller-Ruchholz, W.}, title = {Long-term suppression of natural and graft-induced xenophile antibodies by short-term antigen-cyclophosphamide treatment}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45262}, year = {1993}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{MuellerBuchholtzLeyhausenPetersonetal.1987, author = {M{\"u}ller-Buchholtz, W. and Leyhausen, G. and Peterson, P. and Schubert, G. and Ulrichs, Karin}, title = {A simple methodological principle for large scale extraction and purification of collagenase-digested islets}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44770}, year = {1987}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsNoethlingKelleretal.1987, author = {Ulrichs, Karin and N{\"o}thling, R. and Keller, R. and Heusermann, U. and M{\"u}ller-Buchholtz, W.}, title = {Genetically determined variation of constitutive major histocompatibility complex class II antigen expression in various rat strains and cell types}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44769}, year = {1987}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{EcksteinUlrichsMeinckeetal.1992, author = {Eckstein, V. and Ulrichs, K. and Meincke, G. and M{\"u}ller-Ruchholtz, W.}, title = {Natural xenophile antibodies from sera of type I diabetic patients differ strongly in their reactivity against various porcine pancreatic cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45277}, year = {1992}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{DeltzMuellerHermelinkUlrichsetal.1981, author = {Deltz, E. and M{\"u}ller-Hermelink, HK and Ulrichs, Karin and Thiede, A. and M{\"u}ller-Ruchholtz, W.}, title = {Development of graft-versus-host reaction in various target organs after small intestine transplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45459}, year = {1981}, abstract = {The GVHRIL foHowing transplantation of small intestine are different from those found after bone marrow transplantation or spleen cell injections in that they show a remarka ble, significant prevalence of lesions within the intestinal mucosa. These findings are consistent with the observation that jntestinal lymphocytes newly formed in mesenteric lymph nodes predominantly home in on the intestine again.\& The degree of histologic alteration within different tissues indicates that the graft and the host may survive the lesions of the lymphatic tissues, whereas the severe intestinal lesions following GVHR may easily cause death of the recipient. With regard to clinical sman bowel transplantation two statements can be made: (l) GVHRIL play a significant role in small bowel trans~ plantation. (2) To minimize their biologic importance, a selective elimination of the graft's Jymph nodes by irradiation or surgical resection should be considered in view of the remarkable difference between GVHRIL in lymph nodes and in the graft's intestinal wall itself.}, subject = {Chirurgie}, language = {en} } @article{WaagaKrzymanskiUlrichsetal.1993, author = {Waaga, AM and Krzymanski, M. and Ulrichs, Karin and Wierusz-Wysocka, Bogna and M{\"u}ller-Buchholtz, Wolfgang}, title = {Hematological effects of the new immunosuppressive drug 15-deoxyspergualin}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44701}, year = {1993}, abstract = {Since systematic hematological studies on blood and bone marrow changes after treatment with 15-Deoxyspergualin (DOS) are lacking, a quantitative assessment was performed fourteen or twenty eight days after intraperitoneal application of DOS to rats. Further observations done 7 and 14 days after discontinuation of DOS administration allowed analysis of banc marrow regeneration. DOS induced lymphocytopenia, granUlocytopenia and anemia with a decrease of bone marrow cellularity due to suppression of cell maturation. The effect was dose-dependent and bone marrow as well as blood changes were observed in animals treated with doses from 0.5 to 10.0 mg/kg DOS. Within 14 days after termination of the treatment, rapid recovery with normalization of all hematological parameters was observed. In the light of our data, these hematological side effects may not be a major disadvantage, if DOS is used in doses below 2.5 mg/kg, and for a course of therapy which is limited to 7 to 14 days.}, subject = {Chirurgie}, language = {en} } @article{HeiserUlrichsMuellerBuchholtz1994, author = {Heiser, Axel and Ulrichs, Karin and M{\"u}ller-Buchholtz, Wolfgang}, title = {Isolation of porcine pancreatic islets: low trypsin activity during the isolation procedure guarantees reproducible high islet yields}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44719}, year = {1994}, abstract = {During the past few years, interest in xenotransplantation of porcine islets of Langerhans for the future therapy of type I diabetes has Increased markedly. Therefore, we established a semiautomated digestion method for isolating islets from the porcine pancreas. However, although the isolation technique was standardized and collagenase of controlled quality was used, we were unable to attain high islet yields with a satisfactory degree of reproducibility. One hypothesis was that varying degrees of interference by donor pancreatic enzymes were responsible for this failure. The aim of this stUdy was to examine the kinetics of four types of enzymatic activity during the isolation procedure, as well as their effects on islet yield: collagenase, trypsin, neutral protease, and clostripaln. Our results indicate that while exogenous collagenase activity decreases slightly during the isolation procedure, the activity of the pancreas enzymes neutral protease and trypsin increases. In some cases, trypsin activity increases very strongly. A strong increase in trypsin activity correlates with poor islet yield, whereas low trypsin activity always correlates with high islet yield. Addition of the protease inhibitor Pefabloc to the isolation medium results in low trypsin activity and reproducible high islet yields.}, subject = {Langerhans-Inseln}, language = {en} } @article{WinotoMorbachUlrichsHeringetal.1990, author = {Winoto-Morbach, S. and Ulrichs, Karin and Hering, BJ and Leyhausen, G. and M{\"u}ller-Ruchholtz, W.}, title = {Lectins for electromagnetic purification of islets from humans and large mammals}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45430}, year = {1990}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{UlrichsKellerMuellerRuchholtz1986, author = {Ulrichs, Karin and Keller, R. and M{\"u}ller-Ruchholtz, W.}, title = {Vorkommen und Manipulation von MHC Klasse II Antigenen auf Zellen isolierter Langerhans-Inseln}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45499}, year = {1986}, abstract = {No abstract available}, subject = {Langerhans-Inseln}, language = {de} } @article{UlrichsMuellerRuchholtz1990, author = {Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Mixed lymphocyte islet culture (MLIC) and its use in manipulation of human islet alloimmunogenicity}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45515}, year = {1990}, abstract = {No abstract available}, language = {en} } @article{UlrichsKuhlencordtMuellerRuchholtz1979, author = {Ulrichs, Karin and Kuhlencordt, KM and M{\"u}ller-Ruchholtz, W.}, title = {Plating inhibition assay (PIA): a new test for cell mediated cytotoxicity}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45443}, year = {1979}, abstract = {No abstract available}, language = {en} } @article{UlrichsDeltzThiedeetal.1982, author = {Ulrichs, Karin and Deltz, E. and Thiede, A. and M{\"u}ller-Ruchholtz, W.}, title = {Lymphoid tissue transplantation in rats leads to a GVHR, inducing a specific T-cell mediated autoreactivity against MHC-antigens}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45420}, year = {1982}, abstract = {No abstract available}, language = {en} } @article{UlrichsMuellerBuchholtz1985, author = {Ulrichs, Karin and M{\"u}ller-Buchholtz, W.}, title = {MHC class II antigen expression on the various cells of normal and activated isolated pancreatic islets}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44722}, year = {1985}, abstract = {It is the aim of this study to characterize and quantify the cells within isolated rat islets that express MHC class 11 antigens. A set of five monoelonal antibodies and two polyclonal antisera of defined specificlty were used in combination with a newly devised procedure for three·dimensional immunofluorescence evaluation of intact islets. It is shown that in addition to passen· ger cells, such as Iymphocytes, macro· phages, and dendrlticlike cells, vascular endothelial and endocrine cells are also capable of expressing class 11 antigens. This expression Is strongly influenced by in vitro culture. pregnancy, streptozotocin- induced diabetes, transplantation trauma, and alloantigenic stimuli. The pos· sible role of the above cells in antigen presentation related to islet transplantation is discussed.}, language = {en} } @article{Burschka1980, author = {Burschka, Christian}, title = {Kristallstruktur von NH\(_4\)CuS\(_4\)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46763}, year = {1980}, abstract = {NH4CuS4 was prepared according to syntheses reported in the literature. Orthorhombic crystals could be grown (P21 21 21 , a = 5.249(1), b = 8.444(2), c = 12.782(2) A, Z = 4), the structure of which was solved from X-ray diffractometer data. (R = 0.031 for 767 obs. reflections). In the solid state (CuS4)- chelate rings are linked via additional Cu-S-bonds to form one-dimensional polymerie anions.}, subject = {Chemie}, language = {de} } @article{UlrichsSchangKelleretal.1984, author = {Ulrichs, Karin and Schang, T. and Keller, R. and M{\"u}ller-Ruchholtz, W.}, title = {Reactivity of pancreas islet cells with antisera of known specificity}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45466}, year = {1984}, abstract = {No abstract available}, language = {en} } @article{EngemannGasselUlrichsetal.1986, author = {Engemann, R. and Gassel, HJ and Ulrichs, Karin and Thiede, A. and Hamelmann, H.}, title = {Suppressorzellmechanismen nach Cyclosporin A (CsA) induzierter Toleranz allogener Rattenlebertransplantate}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45503}, year = {1986}, abstract = {No abstract available}, language = {de} } @article{HeiserUlrichsMuellerRuchholtz1994, author = {Heiser, A. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Prophylactic trypsin inhibition during the isolation procedure guarantees reproducible, high porcine islet yields}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45531}, year = {1994}, abstract = {Abstract: For isolating islets from the porcine pancreas, we established a semiautomated digestion method. Although the isolation technique was standardized and collagenase of controlled quality was used, until now the reproducibility of high islet yields was unsatisfactory. Our hypothesis was that pancreatic trypsin was responsible for this failure. The aim of this study was to investigate the effect of endogenous trypsin on islet yield. Our results demonstrate that a high trypsin level correlates with poor islet yield, whereas low trypsin activity always correlates with high islet yield. Specific inhibition of trypsin results in low trypsin activity and reproducible, high islet yields.}, language = {en} } @article{EngemannUlrichsThiedeetal.1990, author = {Engemann, R. and Ulrichs, Karin and Thiede, A. and M{\"u}ller-Ruchholtz, W. and Hamelmann, H.}, title = {Value of a physiological liver transplant model in rats. Induction of specific graft tolerance in a fully allogeneic strain combination}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45622}, year = {1990}, abstract = {No abstract available}, language = {en} } @article{UlrichsYuDunckeretal.1984, author = {Ulrichs, Karin and Yu, MY and Duncker, D. and M{\"u}ller-Ruchholtz, W.}, title = {Immunosuppression by cytostatic drugs?}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45574}, year = {1984}, abstract = {In the present study, an attempt was made to characterize the immunomodulating abilities of the cytostatic drugs cydophosphamide, ifosfamide, vinblastine, vincristine, procarbazine, dacarbazine, 6-mercaptopurine, methotrexate, 5-f/uor-uracil and adriamycine in a defined experimental model. Varying combinations of drug plus transplantation alloantigen, (C3H-lymphocytes) were injected into Balb/c mice at different time intervals in vivo. The resulting T-effector cell reactivity was determined in vitro with the microcytotoxicity assay on day + 5 for primary (r) and day + 7 for secondary (2°) sensitized mice. According to the type of drug (alkylating agent vs. vinca alkaloid vs. antimetabolite vs. cytostatic antibiotic), the dosage (20\% LD50 vs. 60\% LD50), the state of sensitization (r vs. 2° sensitized recipients), and the time of drug application in relation to the antigen treatment on day 0 (in varying steps from day -6 to day +4), so-called "pharmaconantigen- variation-effects" (PA VE) were established for each of the investigated drugs in form of reaction profiles. The results were as folIows: (1) For almost alt substances, characteristic reaction profiles involving immunostimulation and/or immunosuppression could be established. Similarities in the profiles of different substances made it possible to classify the drugs according to different reaction types. The reaction type however is not definitely correlated to the biochemical mechanism of drug action. (2) The PA VE are decisively inf/uenced by so me of the biological parameters, such as the time of drug application in relation to the antigen treatment and the state of sensitization but relatively !ittle by the dosage of the drug. (3) Considering the different processes occurring du ring primary and secondary immune responses, the PAVE may give hints for a distinct manipulation of the immunoregulation and thus information on the immunobiological mechanism of drug action.}, subject = {Immunologie}, language = {en} } @article{LiebertSchneiderSchauliesterMeulen1988, author = {Liebert, U. G. and Schneider-Schaulies, Sibylle and ter Meulen, V.}, title = {Measles Virus infections of the central nervous system (CNS) of rats}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-34087}, year = {1988}, abstract = {No abstract available}, subject = {Masernvirus}, language = {en} } @article{SchneiderSchauliesLiebertBaczkoetal.1988, author = {Schneider-Schaulies, Sibylle and Liebert, U. G. and Baczko, K. and ter Meulen, Volker}, title = {Molecular Biological Analyses of Measles Virus Gene Expression in the CNS of Acutely and Persistently Infected Rat Brain Cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-34104}, year = {1988}, abstract = {No abstract available}, subject = {Masernvirus}, language = {en} } @article{MuellerStahlHennigRethwilmetal.1991, author = {M{\"u}ller, J. G. and Stahl-Hennig, Christiane and Rethwilm, Axel and Kneitz, C. and Kerkau, Thomas and Schmauser, B. and Schindler, C and Krenn, V. and terMeulen, V. and M{\"u}ller-Hermelink, H.K.}, title = {Morphologische Untersuchungen von Lymphknoten und Thymusin der Fr{\"u}hphase der SIV-Infektion bei Rhesus-Affen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47183}, year = {1991}, abstract = {Rhesus monkeys (M. mulatta) were i. v. infected with SIV mac251. Three phases of lymph node changes were observed. 1: physiological follicular hyperplasia (3 and 6 weeks p.i.). 2: Alterations of germinal centers: loss of follicular mantle zone, fragmentation or sclerosis (12 and 24 weeks p.i.). 3: Partial depletion of T-lymphocytes, accumulation of plasma cells, increased numbers of syncytial giant cells, hemophgocytosis in the sinuses (about 1 year p.i.). The thymus of the juvenile animals showed first changes 12 and 24 weeks after infection with focalloss of immature (and Ki-67 positive) cortical thymocytes, leading to severe accidental involution of the thymuses one year after infection and reduced numbers of Hassalls corpuscles. These investigations show the value of this animal model for the study of morphology and pathogenesis of AIDS.}, subject = {Affenimmundefizienzvirus}, language = {de} } @article{Hommers1988, author = {Hommers, Wilfried}, title = {Implicit psychological theories in legal thought on sentencing and liability}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47093}, year = {1988}, abstract = {No abstract available}, subject = {Haftung}, language = {en} } @article{OeschgerFacklerHameretal.1990, author = {Oeschger, Bernhard and Fackler, Guido and Hamer, Jens and Burkhard, Antje}, title = {Die Landesstelle f{\"u}r Volkskunde Freiburg 1960-1990}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41796}, year = {1990}, abstract = {No abstract available}, subject = {Volkskunde}, language = {de} } @article{HeckFackler1993, author = {Heck, Brigitte and Fackler, Guido}, title = {Zwischen Schule und Fabrik - Textile Frauenarbeit in Baden : Eine volkskundliche Sonderausstellung in Baden}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41844}, year = {1993}, abstract = {No abstract available}, subject = {Frauenarbeit}, language = {de} } @article{RandlkoferJordanMitesseretal.2009, author = {Randlkofer, Barbara and Jordan, Florian and Mitesser, Oliver and Meiners, Torsten and Obermaier, Elisabeth}, title = {Effect of vegetation density, height, and connectivity on the oviposition pattern of the leaf beetle Galeruca tanaceti}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49665}, year = {2009}, abstract = {Vegetation structure can profoundly influence patterns of abundance, distribution, and reproduction of herbivorous insects and their susceptibility to natural enemies. The three main structural traits of herbaceous vegetation are density, height, and connectivity. This study determined the herbivore response to each of these three parameters by analysing oviposition patterns in the field and studying the underlying mechanisms in laboratory bioassays. The generalist leaf beetle, Galeruca tanaceti L. (Coleoptera: Chrysomelidae), preferentially deposits its egg clutches on non-host plants such as grasses. Earlier studies revealed that oviposition within structurally complex vegetation reduces the risk of egg parasitism. Consequently, leaf beetle females should prefer patches with dense, tall, or connected vegetation for oviposition in order to increase their reproductive success. In the present study, we tested the following three hypotheses on the effect of stem density, height, and connectivity on oviposition: (1) Within habitats, the number of egg clutches in areas with high stem densities is disproportionately higher than in low-density areas. The number of egg clutches on (2) tall stems or (3) in vegetation with high connectivity is higher than expected for a random distribution. In the field, stem density and height were positively correlated with egg clutch presence. Moreover, a disproportionately high presence of egg clutches was determined in patches with high stem densities. Stem height had a positive influence on oviposition, also in a laboratory two-choice bioassay, whereas stem density and connectivity did not affect oviposition preferences in the laboratory. Therefore, stem height and, potentially, density, but not connectivity, seem to trigger oviposition site selection of the herbivore. This study made evident that certain, but not all traits of the vegetation structure can impose a strong influence on oviposition patterns of herbivorous insects. The results were finally compared with data on the movement patterns of the specialised egg parasitoid of the herbivore in comparable types of vegetation structure.}, subject = {Blattk{\"a}fer}, language = {en} } @article{LambeetsVandegehuchteMaelfaitetal.2008, author = {Lambeets, Kevin and Vandegehuchte, Martijn L. and Maelfait, Jean-Pierre and Bonte, Dries}, title = {Understanding the impact of flooding on trait-displacements and shifts in assemblage structure of predatory arthropods on river banks}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49580}, year = {2008}, abstract = {1. Species assemblages of naturally disturbed habitats are governed by the prevailing disturbance regime. Consequently, stochastic flood events affect river banks and the inhabiting biota. Predatory arthropods occupy predominantly river banks in relation to specific habitat conditions. Therefore, species sorting and stochastic processes as induced by flooding are supposed to play important roles in structuring riparian arthropod assemblages in relation to their habitat preference and dispersal ability. 2. To ascertain whether assemblages of spiders and carabid beetles from disturbed river banks are structured by stochastic or sorting mechanisms, diversity patterns and assemblage-wide trait-displacements were assessed based on pitfall sampling data. We tested if flooding disturbance within a lowland river reach affects diversity patterns and trait distribution in both groups. 3. Whereas the number of riparian spider species decreased considerably with increased flooding, carabid beetle diversity benefited from intermediate degrees of flooding. Moreover, regression analyses revealed trait-displacements, reflecting sorting mechanisms particularly for spiders. Increased flooding disturbance was associated with assemblage-wide increases of niche breadth, shading and hygrophilic preference and ballooning propensity for spider (sub)families. Trait patterns were comparable for Bembidiini carabids, but were less univocal for Pterostichini species. Body size decreased for lycosid spiders and Bembidiini carabids with increased flooding, but increased in linyphiid spiders and Pterostichini carabids. 4. Our results indicate that mainly riparian species are disfavoured by either too high or too low degrees of disturbance, whereas eurytopic species benefit from increased flooding. Anthropogenic alterations of flooding disturbance constrain the distribution of common hygrophilous species and/or species with high dispersal ability, inducing shifts towards less specialized arthropod assemblages. River banks with divergent degrees of flooding impact should be maintained throughout dynamic lowland river reaches in order to preserve typical riparian arthropod assemblages.}, subject = {Flussufer}, language = {en} } @article{LambeetsVandegehuchteMaelfaitetal.2009, author = {Lambeets, Kevin and Vandegehuchte, Martijn L. and Maelfait, Jean-Pierre and Bonte, Dries}, title = {Integrating environmental conditions and functional life-history traits for riparian arthropod conservation planning}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-50148}, year = {2009}, abstract = {River banks are naturally disturbed habitats, in which local flood events and the landscape structure are expected to govern riparian species assemblages. Not solely effects of flooding per se, but also related changes in vegetation structure will affect species' distribution. By elucidating the relationships between species' occurrence and multivariate habitat conditions on a restricted spatial scale, insight into conservation strategies to preserve riparian species is gained. Ordination and grouping methods revealed important environmental and functional trait constraints on species composition of predatory riparian arthropod assemblages. Mainly flooding disturbance appeared to affect spider and carabid beetle species composition. Habitat affinity and dispersal ability were retained as important traits explaining similarity between arthropod assemblages. River banks similar in species composition differed in absolute and functional group species richness. Furthermore, Poisson regressions demonstrated the importance of variation in discharge regime, sediment composition and vegetation structure for the preservation of rare riparian arthropods. Whereas hygrophilic species benefited from increased vegetation cover, xerothermophilic specialists were favoured by increased flooding disturbance. In contrast to flight-active riparian carabids occurring throughout the river system, especially cursorial spiders are expected to go extinct under increased anthropogenic alterations of discharge regimes. We show the importance of a dynamic and evidence-based approach of river management on a local scale to preserve vulnerable riparian arthropods. In general, river restoration should generate the required heterogeneity in environmental conditions (e.g. dynamic processes) at the river bank level, thereby increasing the sustainability of riverine landscapes. More-over, we argue that the understanding of functional responses towards environmental factors results in general and widely applicable guiding concepts for species conservation.}, subject = {Laufk{\"a}fer}, language = {de} } @article{WinotoMorbachUlrichsLeyhausenetal.1989, author = {Winoto-Morbach, Supandi and Ulrichs, Karin and Leyhausen, Gaby and M{\"u}ller-Ruchholtz, Wolfgang}, title = {New principle for large-scale preparation of purified human pancreas islets}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45600}, year = {1989}, abstract = {Because successful human islet transplantation requires large quantities of viable islets that must be separated from the highly immunogenic exocrine tissue and because handpicking is too time-consuming and laborious to be clinically relevant, a new approach for solving this problem has been established in rat models. It is based on the principle that magnetic microspheres (MMSs) coupled to lectins with binding specificity for the exocrine tissue portion are trapped in an electromagnetic field, thus providing effluent islets of a high degree of purity. In this study our aim was to adapt this princip'le to human islet preparations. In this context our prime interest was focused on a lectin suitable for human pancreatic tissue. Of 19 different lectins tested, only 1, Wisteria floribunda agglutinin (WFA), is suitable, as shown by immunofluorescence, MMS-Iectin binding, and magnetic separation}, subject = {Immunbiologie}, language = {en} } @article{HeisswolfUlmannObermaieretal.2007, author = {Heisswolf, Annette and Ulmann, Sandra and Obermaier, Elisabeth and Mitesser, Oliver and Poethke, Hans J.}, title = {Host plant finding in the specialised leaf beetle Cassida canaliculata: an analysis of small-scale movement behaviour}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49485}, year = {2007}, abstract = {1. Host plant finding in walking herbivorous beetles is still poorly understood. Analysis of small-scale movement patterns under semi-natural conditions can be a useful tool to detect behavioural responses towards host plant cues. 2. In this study, the small-scale movement behaviour of the monophagous leaf beetle Cassida canaliculata Laich. (Coleoptera: Chrysomelidae) was studied in a semi-natural arena (r = 1 m). In three different settings, a host (Salvia pratensis L., Lamiales: Lamiaceae), a non-host (Rumex conglomeratus Murr., Caryophyllales: Polygonaceae), or no plant was presented in the centre of the arena. 3. The beetles showed no differences in the absolute movement variables, straightness and mean walking speed, between the three settings. However, the relative movement variables, mean distance to the centre and mean angular deviation from walking straight to the centre, were significantly smaller when a host plant was offered. Likewise, the angular deviation from walking straight to the centre tended to decline with decreasing distance from the centre. Finally, significantly more beetles were found on the host than on the non-host at the end of all the trials. 4. It is concluded that C. canaliculata is able to recognise its host plant from a distance. Whether olfactory or visual cues (or a combination of both) are used to find the host plant remains to be elucidated by further studies.}, subject = {K{\"a}fer}, language = {en} } @article{VonGaudeckerUlrichsMuellerRuchholtz1989, author = {Von Gaudecker, Brita and Ulrichs, Karin and M{\"u}ller-Ruchholtz, Wolfgang}, title = {Immunoelectron microscopic localization of MHC structures in isolated pancreatic rat islets}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45596}, year = {1989}, abstract = {An immunogold-silver enhancement technique, which combines effective labeling of viable isolated islets with the ultrastructural resolution of cytological details, was applied in electron microscopy to identify major histocompatibility complex (MHC) structures on islet cells. Incubation of freshly isolated islets from CAP (RT1C) and LEW (RT1') rats with OX18, an MHC class I antibody, showed strong positive reactivity in macrophages and/or dendritic-like cells (M0-DCs) and vascular endothelial cells (VEs) and a comparatively weaker reactivity in endocrine a-, p-, and 8-ce"s. With MHC class" antibody OX6 (anti-I-A), M0-DCs were strongly labeled in both rat strains on the surface and on internal structures. Three of five particularly high titered batches of OX6 revealed MHC class" expression on VE and p-ce"s. Four days of in vitro culture in combination with a high concentration of glucose and interferon-'Y induced strong enhancement of MHC class I structures and, to a lesser extent, class " structures on p-ce"s.}, subject = {Immunbiologie}, language = {en} } @article{KekowUlrichsMuellerRuchholtzetal.1988, author = {Kekow, J{\"o}rn and Ulrichs, Karin and M{\"u}ller-Ruchholtz, Wolfgang and Gross, Wolfgang L.}, title = {Measurement of rat insulin. Enzyme-linked immunosorbent assay with increased sensitivity, high accuracy, and greater practicability than established radioimmunoassay}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45543}, year = {1988}, abstract = {Total immunoreactive insulin (IRI) is conventionally determined by radioimmunoassays. IR! measurement in rats can be made more sensitive, accurate, and practical, as demonstrated by a new modified enzyme-linked immunosorbent assay (ELlSA). It is characterized by indirect binding of an anti-insulin antibody by an antiglobulin antibody and uses the principle of competitive saturation. In this ELlSA, IRI can be determined in a wide range of concentrations, corresponding to the standards. The standard curve ranges from 100 to 0.049 ng/mllRI (1 ng/ml - 23.4 JLU/ml - 172 pM rat insulin). The statistical analysis shows between- and within-assay coefficients of variation of :515\%. Diabetes 37:321-26,1988}, subject = {Chirurgie}, language = {en} } @article{HeisswolfGablerObermaieretal.2007, author = {Heisswolf, Annette and Gabler, Dirk and Obermaier, Elisabeth and M{\"u}ller, Caroline}, title = {Olfactory versus contact cues in host plant recognition of a monophagous chrysomelid beetle}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49475}, year = {2007}, abstract = {The importance of olfactory versus contact cues for host plant recognition was investigated in the tortoise beetle Cassida canaliculata Laich. (Coleoptera: Chrysomelidae), which is strictly monophagous on meadow sage. The reaction of adult beetles to olfactory and contact host cues was tested using three bioassays (locomotion compensator, six-chamber-olfactometer, stem arena') to account for different behavioral contexts. Bioassay-guided fractionation of plant extracts was elaborated to characterize the nature of contact stimuli. The beetles were only slightly attracted to odors from small amounts of leaf material. However, when contact cues were provided additionally, the beetles showed strong preferences for samples of their host plant over controls. Bioassay-guided fractionation led to isolation of at least two non-polar contact stimuli acting in concert that are sufficient for host plant identification in C. canaliculata.}, subject = {Insekt}, language = {en} } @article{Smasal2010, author = {Smasal, Marc}, title = {Lernstrategien im Fremdsprachenunterricht. Ein Workshop f{\"u}r die f{\"a}cher{\"u}bergreifende Aus- und Weiterbildung von Fremdsprachenlehrkr{\"a}ften}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49822}, year = {2010}, abstract = {Der Workshop zielt auf die handlungsorientierte Vermittlung deklarativen, prozeduralen und konditionalen Wissens {\"u}ber Lernstrategien in der Lehrerausbildung ab. Lehrkr{\"a}fte k{\"o}nnen das Konzept des Workshops auf ihren Fremdsprachenunterricht {\"u}bertragen und die Aktivit{\"a}ten den entsprechenden Anforderungen anpassen. Im Rahmen des Workshops arbeiten die Teilnehmerinnen und Teilnehmer an kognitiv anspruchsvollen Aufgaben und werden durch die Instrumentalisierung der polnischen Sprache in die Rolle von Fremdsprachenlernern im Anf{\"a}ngerunterricht zur{\"u}ckversetzt. Dadurch eignet sich der Workshop f{\"u}r Ausbildungsmaßnahmen, bei denen Lehrkr{\"a}fte unterschiedlicher Fremdsprachen teilnehmen. Der Workshop basiert auf der Annahme, dass sich Lehrerinnen und Lehrer ihrer eigenen Lernprozesse und Lernstrategien beim Fremdsprachenlernen bewusst sein sollten, um diese Erfahrungen in ihrer Rolle als Modellerner weitergeben zu k{\"o}nnen und um eine Sensibilit{\"a}t f{\"u}r die Lernschwierigkeiten ihrer Sch{\"u}lerinnen und Sch{\"u}ler entwickeln zu k{\"o}nnen.}, subject = {Fremdsprachenlernen}, language = {de} } @article{Hammer2010, author = {Hammer, Julia}, title = {My presentation ... Presenting in English}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49819}, year = {2010}, abstract = {Das Pr{\"a}sentieren ist eine Lernform, die die wesentlichen Ziele eines autonomen und handlungsorientierten Englischkurses erf{\"u}llt und die als Zentralqualifikation im universit{\"a}ren Bereich und außerakademischen Kontext gefordert wird. In dem vorliegenden Artikel wird auf die Vielfalt der Kompetenzen, die durch das Ein{\"u}ben von m{\"u}ndlichen Pr{\"a}sentationen erarbeitet werden, eingegangen. Pr{\"a}sentieren dient dabei nicht nur der sprachlichen Verbesserung und Routine in der Fremdsprache, sondern auch der allgemeinen Ein{\"u}bung der "Kunst der Pr{\"a}sentation" und der Vermittlung von Wissensinhalten. Die daraus entstehende Rolle der Lehrperson als Mediator im Unterrichtsgeschehen soll, ebenso wie ein Praxisbezug in Form von didaktischen Tipps und Lernerarrangements, nicht außen vor gelassen werden.}, subject = {Pr{\"a}sentation}, language = {de} } @article{Karagiannakis2010, author = {Karagiannakis, Evangelia}, title = {Autonomes Lernen durch Beobachtung, Reflexion und Evaluation des eigenen Lernprozesses - Punktuelle und kontinuierliche Verfahren}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49879}, year = {2010}, abstract = {"Autonomes Lernen ist das {\"U}bernehmen von Verantwortung f{\"u}r das eigene Lernen." (Rieder, o. J.) Bedeutend f{\"u}r den Lernprozess ist weiterhin die F{\"a}higkeit, diesen selbst zu organisieren. Damit Eigenverantwortung und Selbstorganisation gelingen k{\"o}nnen, m{\"u}ssen Lernende ihren Lernprozess regelm{\"a}ßig reflektieren sowie Ergebnisse selbstst{\"a}ndig evaluieren und bewerten. (vgl. Wolff, 1997:3) Von Zeit zu Zeit sollte die gesamte Lerngruppe am Reflexions- und Evaluationsprozess beteiligt werden. Im vorliegenden Beitrag werden Methoden vorgestellt, mit denen teils in Einzelarbeit, teils in der Gruppe schnelle Zwischenevaluationen oder kontinuierlich begleitende Reflexionen realisiert werden k{\"o}nnen.}, subject = {Fremdsprachenlernen}, language = {de} } @article{Werbe2010, author = {Werbe, Franziska}, title = {Eigen- und Fremdevaluation im Rahmen eines Kurses Pr{\"a}sentationstechniken f{\"u}r ausl{\"a}ndische Studierende}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49914}, year = {2010}, abstract = {Der Kurs "Pr{\"a}sentationstechniken" soll ausl{\"a}ndischen Studierenden einen Rahmen bieten, sich mit dem Thema Referat an deutschen Hochschulen vertraut zu machen, sich auszuprobieren und durch {\"U}bung zu verbessern. Ein Schwerpunkt liegt hierbei auf der Eigen- und Fremdeinsch{\"a}tzung der Studierenden. Nachdem gemeinsam Aspekte erarbeitet worden sind, worauf bei einer Pr{\"a}sentation zu achten ist, wird den Studierenden Gelegenheit gegeben, diese Aspekte bei sich selbst sowie bei den Kommilitonen zu {\"u}berpr{\"u}fen. Spontanvortr{\"a}ge sowie ein l{\"a}ngerer, ausgearbeiteter Vortrag dienen als {\"U}bung, um Selbst- und Fremdevaluation zu praktizieren. Feedbackregeln helfen, die R{\"u}ckmeldungen konstruktiv zu gestalten. Zur Selbsteinsch{\"a}tzung dienen Videoaufnahmen, Fremdeinsch{\"a}tzung bietet neben dem direkten, m{\"u}ndlichen Feedback auch schriftliche R{\"u}ckmeldung auf anonymisierten Karten. Die Einsch{\"a}tzung durch die Lehrkraft wird durch einen Bewertungsbogen, der unterschiedliche Aspekte der Pr{\"a}sentation bewertet, durchsichtig gemacht. Eine Evaluation des gesamten Kurses durch die Teilnehmer schließt den Artikel ab. Zur Verdeutlichung dienen zwei im Kurs (WS 09/10) gehaltene Referate mit anschließender Beurteilung.}, subject = {Fremdsprachenlernen}, language = {de} } @article{Tassinari2010, author = {Tassinari, Maria Giovanna}, title = {Checklisten zu Lernerautonomie: Erfahrungen mit der Selbsteinsch{\"a}tzung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49909}, year = {2010}, abstract = {Ist eine Selbsteinsch{\"a}tzung von Lernerautonomie beim Fremdsprachenlernen m{\"o}glich? Von welchen Instrumenten und Methoden k{\"o}nnen Lerner und Lehrer in autonomisierenden Lernprozessen profitieren? In diesem Beitrag stelle ich ein Instrument zur Selbsteinsch{\"a}tzung vor und zwar die Checklisten zu Lernerautonomie. Dieses Instrument enth{\"a}lt ein dynamisches Autonomiemodell mit verschiedenen wissensbasierten, handlungsorientierten und affektiven Komponenten sowie Deskriptoren f{\"u}r Kompetenzen, Strategien und Einstellungen des Lerners zu Lernerautonomie. Die Erprobung dieser Checklisten am Sprachenzentrum der Freien Universit{\"a}t Berlin ergab ein positives Feedback der Studierenden, die von der Selbsteinsch{\"a}tzung Anregungen zur Selbstreflexion und Entscheidungsfindung in ihrem autonomen Lernprozess erhielten. Eine solche Selbsteinsch{\"a}tzung soll durch einen p{\"a}dagogischen Dialog begleitet werden: Der Beitrag zeigt, wie die Selbsteinsch{\"a}tzung erfolgreich im Rahmen einer Sprachlernberatung begleitet wurde.}, subject = {Fremdsprachenlernen}, language = {de} } @article{Sailer2010, author = {Sailer, Wolfram}, title = {epos - das elektronische Portfolio der Sprachen. Ein wichtiges Instrument zur F{\"o}rderung von Lernautonomie beim lebenslangen Sprachenlernen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49896}, year = {2010}, abstract = {Das webbasierte elektronische Portfolio der Sprachen epos, das der Bremer Sprachenrat verantwortet, ist ein Instrument des lebenslangen Sprachenlernens. Es enth{\"a}lt neben allen Elementen eines Papierportfolios einige Features, die es besonders zur F{\"o}rderung der Lernautonomie geeignet werden l{\"a}sst. Dazu geh{\"o}rt, dass es der oder dem Lernenden {\"u}berlassen ist, ob er oder sie seine Sprachenbiographie einem Tutor oder einer Tutorin gegen{\"u}ber offenbart und sie oder ihn zum Kommentar auffordert. Auch Produkte des Sprachenlernens, welche im Dossier abgelegt werden, k{\"o}nnen dem Tutor oder der Tutorin gegen{\"u}ber zum Zweck der Kommentierung offenbart werden - so erweitert sich epos zur Lernplattform, die f{\"u}r Blended E-Learning nutzbar ist. Die Rolle der Tutorinnen und Tutoren wandelt sich vom Instruktor zum Moderator von Lernprozessen - zugleich ver{\"a}ndert sich der Unterricht durch Orientierung auf Produkte hin zum aufgabenorientierten Lernen. Die Einbindung in Konzepte von formativer Leistungsbewertung ist weiter zu entwickeln.}, subject = {Fremdsprachenlernen}, language = {de} } @article{FroehlichHolsteinPilaski2010, author = {Fr{\"o}hlich, Brigitta and Holstein, Silke and Pilaski, Anna}, title = {Lernen bedeutet, sich auf den Weg zu machen - Lernoptimierung als Konzept im Unterricht}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49869}, year = {2010}, abstract = {Als Lehrperson hat man in Kursen ab B2 nicht selten den Eindruck, einen "Schattenboxkampf" f{\"u}r die Motivation der Lernenden zu f{\"u}hren. Und nicht selten kommt man zu dem Schluss: "Gute Lerner sind eben motiviert und schlechte nicht!" Der Artikel stellt Materialien vor, die im Unterricht R{\"a}ume schaffen, in denen den Lernenden ihre Zielvorstellungen und Bewertungen bewusst werden, damit sie eine Vorstellung davon bekommen, in welche Richtung sie selbstst{\"a}ndig weitergehen und wie sie ihr Lernen optimieren k{\"o}nnen.}, subject = {Lernmotivation}, language = {de} } @article{Asano2010, author = {Asano, Yuki}, title = {Bericht einer Aktionsforschung zur F{\"o}rderung autonomen Lernens in einem Japanischkurs — Aspekte selbstreflektierenden Fremdsprachenlernens}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49855}, year = {2010}, abstract = {Der vorliegende Artikel befasst sich mit einer Aktionsforschung, die im Rahmen eines Japanischunterrichts an der Ruhr-Universit{\"a}t Bochum durchgef{\"u}hrt wurde und stellt konkrete Schritte einer Aktionsforschung dar. Die Unterrichtende versucht, anhand der empirischen Daten aus ihrem eigenen Unterricht heraus zu verstehen, inwieweit der von ihr konzipierte und im Kurs regelm{\"a}ßig verwendete Reflexionsbogen das selbstreflektierende Lernen f{\"o}rdert. Außerdem wird der Frage nachgegangen, in welchem Zusammenhang autonomes Lernen mit bestimmten Grammatikvermittlungsmethoden steht. Ist eine induktive Grammatikvermittlung zur F{\"o}rderung autonomen Lernens erforderlich? Was muss gef{\"o}rdert werden, wenn man autonomes Lernen f{\"o}rdern m{\"o}chte? Die in diesem Artikel dargestellten Fragestellungen und Erkenntnisse beziehen sich zwar auf den Japanischunterricht, aber bieten im weiteren Unterrichtskontext ebenfalls einen Ansatzpunkt f{\"u}r die Weiterentwicklung des Fremdsprachenunterrichts. Dar{\"u}ber hinaus bietet Aktionsforschung die M{\"o}glichkeit, nicht nur Sprachlehrforschende im engen Sinne, sondern alle Unterrichtende, die an der forschungsgeleiteten Entwicklung des Unterrichtsgeschehens interessiert sind, in die Forschung mit einzubeziehen, was zur Weiterentwicklung der Fremdsprachenlehr/lernforschung sicherlich beitr{\"a}gt.}, subject = {Fremdsprachenlernen}, language = {de} } @article{ZhuberOkrog2010, author = {Zhuber-Okrog, Karen}, title = {"Der Spaß und das Interesse diese Sprache zu lernen {\"u}berwiegt" - Erfahrungen aus dem Selbstlernprojekt "Erste Schritte Russisch / Erste Schritte Arabisch"}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49839}, year = {2010}, abstract = {In diesem Artikel wird ein betreutes Selbstlernprojekt f{\"u}r Sprachanf{\"a}nger in Arabisch und Russisch beschrieben. Ziel war der eigenverantwortliche Spracherwerb mit Hilfe von Lernsoftware in Verbindung mit pers{\"o}nlicher tutorieller Betreuung von Muttersprachlern. Ein besonderes Augenmerk lag dabei auf der Bewusstmachung des Lernprozesses und der Aufrechterhaltung der Lernmotivation.}, subject = {Neue Medien}, language = {de} } @article{Curbelo2010, author = {Curbelo, Angel G.}, title = {Ayudar a cruzar el puente: Un blog en la clase de lenguas para fomentar la autonom{\´i}a}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49798}, year = {2010}, abstract = {En este art{\´i}culo se presenta un proyecto de blog realizado y compartido entre estudiantes de alem{\´a}n del Goethe Institut de Madrid y estudiantes de ELE del Centro de Lenguas de la Universidad de W{\"u}rzburg.}, subject = {Fremdsprachenunterricht}, language = {es} } @article{Schmenk2010, author = {Schmenk, Barbara}, title = {Bildungsphilosophischer Idealismus, erfahrungsges{\"a}ttigte Praxisorientierung, didaktischer Hiphop? Eine kleine Geschichte der Lernerautonomie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49781}, year = {2010}, abstract = {Der Beitrag gibt einen {\"U}berblick {\"u}ber die aktuelle Diskussion zur Lernerautonomie in der Fremdsprachendidaktik. Die Skizzierung verschiedener Variationen und Auffassungen von Lernerautonomie kann zugleich als kurzer Abriss der Entwicklung des Autonomiegedankens in der Fremdsprachendidaktik gelesen werden.}, subject = {Fremdsprachenunterricht}, language = {de} } @article{Summer2010, author = {Summer, Theresa}, title = {Key Concept: Learner Autonomy}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49773}, year = {2010}, abstract = {Learner autonomy is an important pedagogic concept in foreign language learning and teaching today and in addition, it is considered to be a significant educational goal. For the learner to become autonomous, he must identify, rehearse and apply learning strategies, structure his own learning, and critically reflect upon his own learning processes to then be able to utilise his acquired skills, in and beyond the classroom. Crucially, autonomy is primarily concerned with learning rather than teaching, as its development is viewed to be a cooperative learning process that can be guided (not directed) by the teacher.}, subject = {Fremdsprachenlernen}, language = {en} } @article{PoethkeHovestadt2002, author = {Poethke, Hans J. and Hovestadt, Thomas}, title = {Evolution of density-and patch-size-dependent dispersal rates}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49659}, year = {2002}, abstract = {Based on a marginal value approach, we derive a nonlinear expression for evolutionarily stable (ES) dispersal rates in a metapopulation with global dispersal. For the general case of density-dependent population growth, our analysis shows that individual dispersal rates should decrease with patch capacity and-beyond a certain threshold-increase with population density. We performed a number of spatially explicit, individual-based simulation experiments to test these predictions and to explore further the relevance of variation in the rate of population increase, density dependence, environmental fluctuations and dispersal mortality on the evolution of dispersal rates. They confirm the predictions of our analytical approach. In addition, they show that dispersal rates in metapopulations mostly depend on dispersal mortality and inter-patch variation in population density. The latter is dominantly driven by environmental fluctuations and the rate of population increase. These conclusions are not altered by the introduction of neighbourhood dispersal. With patch capacities in the order of 100 individuals, kin competition seems to be of negligible importance for ES dispersal rates except when overall dispersal rates are low.}, subject = {Metapopulation}, language = {en} } @article{WieberBurschkaBaudis1978, author = {Wieber, Markus and Burschka, Christian and Baudis, Ulrich}, title = {Darstellung und Molek{\"u}lstruktur von 2-Methylthio-1,3,2-benzodithiastibol}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46772}, year = {1978}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{BurschkaBronger1977, author = {Burschka, Christian and Bronger, Welf}, title = {KCu\(_3\)S\(_2\), ein neues Thiocuprat}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46789}, year = {1977}, abstract = {KCu\(_3\)S\(_2\) kann auf dem gleichen Wege synthetisiert werden, auf dem auch verschiedene Alkalithioargentate zu erhalten sind 1,2: Das M{\"u}nzmetall wird im Gemenge mit einem {\"U}berschuß von Alkalicarbonat und Schwefel etwa 1 h im Argonstrom auf 850°C erhitzt. Den erkalteten Schmelzkuchen zieht man mit Wasser aus. Die wasserunl{\"o}slichen Kristalle werden mit Wasser, Alkohol und {\"A}ther gewaschen und im Vakuum getrocknet. Bei Reaktionstemperaturen von 780-850 °C f{\"a}llt KCu\(_3\)S\(_2\) in Form von schwarzen gl{\"a}nzenden Nadeln an. Bei niedrigeren Temperaturen entstehen die schon von W. R{\"u}DORFF3 beschriebenen Verbindungen K\(_3\)Cu\(_8\)S\(_6\) und KCu\(_4\)S\(_3\), die wir hier an Hand ihrer bekannten Pulverdiagramme identifizieren konnten.}, subject = {Chemie}, language = {de} } @article{WieberBaumannBurschka1977, author = {Wieber, Markus and Baumann, Norbert and Burschka, Christian}, title = {Kristall- und Molek{\"u}lstruktur eines koordinationspolymeren 2-Organo-1.3.2-dioxastibols}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46796}, year = {1977}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{BurschkaAkguenPindur1983, author = {Burschka, Christian and Akguen, Eyup and Pindur, Ulf}, title = {Zur Struktur von (Pyrazolinonyl)-(hydroxypyrazolylium)methanperchloraten NMR-,IR-spektroskopische Studien und Kristallstruktur}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46800}, year = {1983}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{Burschka1979, author = {Burschka, Christian}, title = {Zur Kristallstruktur der Thiocuprate K\(_3\)Cu\(_8\)S\(_6\) und Rb\(_3\)Cu\(_8\)S\(_6\)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46819}, year = {1979}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{Burschka1979, author = {Burschka, Christian}, title = {Na\(_3\)Cu\(_4\)S\(_4\) - ein Thiocuprat mit verkn{\"u}pften \(^1 _\infty\)[Cu\(_4\)S\(_4\)]-Ketten}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46828}, year = {1979}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{SchenkLeissnerBurschka1985, author = {Schenk, Wolfdieter A. and Leissner, Johanna and Burschka, Christian}, title = {Vier- und f{\"u}nffach koordinierte Schwefelmonoxid-Komplexe des Rhodiums und Iridiums}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46838}, year = {1985}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{WieberWirthBurschka1985, author = {Wieber, Markus and Wirth, Dieter and Burschka, Christian}, title = {Darstellung und Struktur einiger \(\eta^5\)-Cyclopentadienyldicarbonyleisenbismut-Verbindungen Cp(CO)\(_2\)FeBiX\(_2\) mit f{\"u}nffach koordiniertem Bismutatom}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46840}, year = {1985}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{SchenkRuebBurschka1987, author = {Schenk, Wolfdieter A. and Rueb, Doris and Burschka, Christian}, title = {Die Koordinationschemie C=S-Funktioneller Verbindungen: VI. Reaktionen an \(\eta^1-, \eta^2\)- und \(\eta^3\)-Dithioester-Komplexen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46699}, year = {1987}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{SingerHeusingerMosandletal.1987, author = {Singer, Gabriele and Heusinger, Georg and Mosandl, Armin and Burschka, Christian}, title = {Stereoisomere Aromastoffe: XVI. Struktur und Eigenschaften optisch reiner 2-Methyl-4-propyl-1,3-oxathian-3-oxide}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46684}, year = {1987}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{SchenkKuemmerleBurschka1988, author = {Schenk, Wolfdieter A. and Kuemmerle, Dagmar and Burschka, Christian}, title = {Die Koordinationschemie C=S-funktioneller Verbindungen: VIII. Addition aktivierter Alkine an Wolfram-CS\(_2\)-Komplexe und Aufbau tetraedrischer Methylidindicobaltwolfram-Cluster}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46676}, year = {1988}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{WernerOttoTrietal.1984, author = {Werner, H. and Otto, H. and Tri, Ngo Khac and Burschka, Christian}, title = {Synthese und Eigenschaften neuer Kupfer- und Gold- Komplexe des Typs C\(_5\)H\(_5\)MPR\(_3\), C\(_5\)Me\(_5\)MPR\(_3\) und R"C\(_2\)MPR\(_3\)(M=Cu,Au)sowie die Kristallstruktur von C\(_5\)H\(_5\)AuPPr\(_3\)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46666}, year = {1984}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{HommersAnderson1985, author = {Hommers, Wilfried and Anderson, Norman H.}, title = {Recompense as a factor in assigned punishment}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43538}, year = {1985}, abstract = {Children's judgements of deserved punishment were studied as function of three moral variables. Subjects judged how much a child in a story should be punished for ruining another's stamps, given information about (a) how many stamps were damaged, (b) the culpa, or intent, of the harmful act, and (c) recompense, or the proportion of stamps paid back by the offender. In three experiments, recompense had substantially greater effects than the damage for which recompense was made. This pre-potency of recompense was greater at younger ages across a range from 4 years to college age. Damage and culpa were integrated by an additive rule in agreement with previous work. In contrast, the recompense-damage and recompense-culpa integration rules were both non-additive.}, language = {en} } @article{Hommers1987, author = {Hommers, Wilfried}, title = {Anti-Typen: Zur psychologischen Validit{\"a}t eines methodischen Konstrukts der Konfigurationsfrequenzanalyse}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43437}, year = {1987}, abstract = {Das Konzept des Anti-Typus wird theoretisch und empirisch-analytisch untersucht. Empirische Grundlage bilden Problem-Kommentierungen zur Erfassung von Therapiemotivationskonstrukten und Antworten auf Fragen eines multivariaten Pers{\"o}nlichkeits-Inventars von 187 Jugendgerichtlich-Inhaftierten und 361 Polizeianw{\"a}rtern. Im ersten Schritt des analytischen Teils werden mit der Konfigurationsfrequenzanalyse (KFA) Hypothesen {\"u}ber Typen und Anti-Typen von Selbstbeschreibungskonstrukten zur Therapiemotivation gewonnen. Zus{\"a}tzlich werden die Inventar-Profile der dabei gebildeten typologischen Pbn-Gruppen multidimensional skaliert und multivariat auf Unterschiedlichkeit gepr{\"u}ft. Im zweiten Schritt werden die KFA-Hypothesen {\"u}ber die Typen und Anti-Typen der "Therapiemotivation" mit Hilfe eines Bayes-statistischen Verfahrens durch ihre Trennung von einer Restgruppe gepr{\"u}ft. Die Inventar-Profile der entstehenden Gruppen werden erneut multidimensional und multivariat verglichen. Von den zwei Bedeutungen des "Anti" im Anti-Typ-Begriff bew{\"a}hrt sich die geometrische Interpretation des "Anti" an den Profilen nicht. Die Interpretation "konsistenter Andersartigkeit" dagegen kann auf der Grundlage der Bayes-statistischen Klassifikation beibehalten werden. Die Untersuchung des Anti-Typ-Begriffs lohnt m{\"o}glicherweise auch in anderen Bereichen.}, subject = {Psychologische Diagnostik / Psychologie / Differentielle Psychologie / Zeitschrift}, language = {de} } @article{KreftHaasGoebel1989, author = {Kreft, J{\"u}rgen and Haas, Albert and Goebel, Werner}, title = {Isolation and characterization of genes coding for proteins involved in the cytolysis by Listeria ivanovii}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46991}, year = {1989}, abstract = {We established a library of chromosomal DNA of Listeria ivanovii in the pTZ19R plasmid system, using Escherichia coli DH5alpha as the host. One recombinant clone reacted strongly with a polyclonal antiserum raised against the listeriolysin 0 and a second exoprotein (24kDa) of L. ivanovii, which is most probably also involved in cytolytic processes. The recombinant E. coli clone may contain part of the listeriolysin 0 gene of L. ivanovii.}, language = {en} } @article{KreftFunkeSchlesingeretal.1989, author = {Kreft, J{\"u}rgen and Funke, D. and Schlesinger, R. and Lottspeich, F. and Goebel, Werner}, title = {Purification and characterization of cytolysins from Listeria monocytogenes serovar 4b and Listeria ivanovii}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47036}, year = {1989}, abstract = {Several exoproteins from Listeria monocytogenes serovar 4b (NCTC 10527) and Listeria ivanovii (ATCC) 19119, SLCC 2379), respectively, have been purified to homogeneity by thiol-disulfide exchange chromatography and gel filtration. Both strains produce a haemolytic/cytolytic protein of Mr 58 kDa, which has all the properties of a SH-activated cytolysin, the prototype of which is streptolysin 0 (SLO), and this protein has therefore heen termed Iisteriolysin 0 (LLO). In addition a protein of Mr 24 kDa from culture supernatants of L. ivanovii co-purified withLLO. The N-terminal aminoacid sequences of both proteins from L. ivanovii have been determined. By mutagenesis with transposons of Gram-positive origin (Tn916 and TnI545), which have been introduced via conjugation into L. ivanovii, several phenotypic mutants (altered haemolysis on sheep blood agar or lecithinase-negative) were obtained. Results on the properties of these muntants will he presented.}, language = {en} } @article{KreftHughes1982, author = {Kreft, J{\"u}rgen and Hughes, Colin}, title = {Cloning vectors derived from plasmids and phage of Bacillus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47014}, year = {1982}, abstract = {No abstract available}, language = {en} } @article{KreftBernhardGoebel1978, author = {Kreft, J{\"u}rgen and Bernhard, K. and Goebel, Werner}, title = {Recombinant plasmids capable to replication in B. subtilis and E. coli}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47000}, year = {1978}, abstract = {The plasmid pBC16 (4.25 kbases), ongtnally isolated from Bacillus cereus, determines tetracycline resistance and can be transformed into competent cells of B. subtilis. A miniplasmid of pBCl6 (pBCI6-1), 2,7 kb) which has lost an EcoRI fragment of pBCI6 retains the replication functions and the tetracycline resistance. This plasmid which carries only one EcoRI site has been joined in vitro to pBS], a cryptic plasmid previously isolated from B. subtilis and shown to carry also a single EcoRI site (Bernhard et aI., 1978). The recombinant plasmid is unstable and dissociates into the plasmid pBSl61 (8.2 kb) and the smaller plasmid pBS162 (2. I kb). Plasmid pBS161 retains the tetracycline resistance. It possesses a single EcoRI site and 6 HindlII sites. The largest HindIII fragment of pBS161 carries the tetracycline resistance gene and the replication function. After circularization in vitro of this fragment a new plasmid, pBS161-l is generated, which can be used as a HindlII and EcoRI cloning vector in Bacillus suhtilis. Hybrid plasmids consisting of the E. coli plasmids pBR322, p WL 7 or pACl84 and different HindlII fragments of pBSI61 were constructed in vitro. Hybrids containing together with the E. coli plasmid the largest HindlII fragment of pBS161 can replicate in E. coli and B. sublilis. In E. coli only the replicon of the E. coli plasmid part is functioning whereas in B. suhtilis replication of the hybrid plasmid is under the control of the Bacillus replicon. The tetracycline resistance of the B. subtilis plasmid is expressed in E. coli, but several antibiotic resistances of the E. coli plasmids (ampicillin, kanamycin and chloramphenicol) are not expressed in B. suhtilis. The hybrid plasmids seem to be more unstable in B. subtilis than in E. coli.}, language = {en} } @article{Kreft1980, author = {Kreft, J{\"u}rgen}, title = {Reovirus-specific messenger ribonucleoprotein particles from Hela cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47028}, year = {1980}, abstract = {When reovirus-infected Hela cells are incubated at 43°C virus-specific messenger RNA is released ~rom the polysomes. It accumulates free in the cytoplasm as messenger ribonucleoprotem partIcles (mRNPs). The:e part~cles have a sedimentati~n rate of about 50S and a buoyant densIty m CsCI of 1.42 g/cm . ReovIrus mRNPs contam, beSIdes all three size classes of reovirus messenger RNA, the same spectrum of proteins found in the polysomal mRNPs from uninfected cells, plus t~o addi~ional pr?teins with molecular masses of 7000~ d and 110000 d, respectively. Electron mIcroscoPIc exammatlOn of the reovIrus mRNP fractIOn reveals specific Y-shaped structures wIth a total mean length ofO.5Ilm.}, language = {en} } @article{KreftGoebel1974, author = {Kreft, J{\"u}rgen and Goebel, Werner}, title = {Complex Co1E1 DNA in Escherichia coli and Proteus mirabilis}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47044}, year = {1974}, abstract = {Incubation of the colicinogenic Escherichia coli strain JC 411 (ColE1) at elevated temperatures (47-49°) leads to the accumulation of catenated molecules and replicative intermediates of this plasmid. Mature supercoiled OolE1 DNA molecules synthesized under these conditions have an increased number of tertiary turns as shown by electron microscopy. The monomeric tightly supercoiled molecules possess a slightly slower sedimentation rate and a higher binding capacity for ethidium bromide than supercoiJed monomers synthesized at lower temperatures. Recombination deficient mutants of E. coli recA, recB and recC, which carry the ColE1 plasmid, form about the same amount of catenated molecules at the elevated temperature as a rec+ strain. In addition, we have observed by electron microscopy a small percentage (.--.5\% of the circular DNA molecules) of minicircular DNA molecules in all preparations of JC 411 (CoIE1). They are homogenous in size, with a molecular weight of 1.4 X 106 daltons. Addition of chloramphenicol to a culture of Proteus mirabilis (ColE1) leads to an increased amount of higher multiple circular oligomers and to a stimulated accumulation of catenated OolE1 DNA molecules of varying sizes. ColE1 DNA synthesis is more thermosensitive than chromosomal DNA replication in P. mirabili8. Plasmid replication stops completely at temperatures above 43°C.}, language = {en} } @article{KutateladzeAxelrodGorboulevetal.1979, author = {Kutateladze, T. V. and Axelrod, V. D. and Gorboulev, Valentin G. and Belzhelarskaya, S. N. and Vartikyan, R. V.}, title = {New procedure of high-voltage electrophoresis in polyacrylamide gel and its application to the sequencing of nucleic acids}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46927}, year = {1979}, abstract = {Fractionation of nucleic acids and their fragments with polyacrylamide gel has been widely applied in sequencing of nucleic acids. Although the conditions of electrophoresis for this purpose have previously been suggested. we have found that polyacrylamide gel electrophoresis at 5000 V (100 V/cm) is possible and effective. An apparatus consisting of a horizontal thermostated plate is used to remove the heat which was formed during the electrophoretic process. The techniques for loading samples on the horizontal thin gel and the procedure for high-voltage gel electrophoresis are described and illustrated by the fractionation of the spleen phosphodiesterase partial digest of tRNA¥~1 as well as by the RNA synthesis by RNA polymerase from E. coli with poly[d(A- T)j as template in the presence of "terminator," 3'-O-methyluridine 5'-triphosphate. This same technique was used for electrophoresis of oligonucleotides on acetylcellulose and was incorporated into a two-dimensional system which was demonstrated by fingerprinting of the guanylo-RNase digest of tRNAT'P from baker's yeast. In the third part of the article a simple technique for the electric trapping of nucleic acids or their fragments from a slab gel on a DEAE-paper sheet is presented.}, language = {en} } @article{ArtyukovaGorboulevRodionovaetal.1985, author = {Artyukova, E. V. and Gorboulev, Valentin G. and Rodionova, N. P. and Krylov, A. V. and Atabekov, J. G.}, title = {Comparative study of structural peculiarities and translation of potexvirus RNAs}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46985}, year = {1985}, abstract = {Structural peculiarities of the S'-end segments of genomic RNA were studied in F potato virus (F-PV) and white clover mosaic virus (WCMV). The methods of affinity chromatography on oligo(dT) cellulose and oligonucleotide mapping revealed a prolonged (up to 210 nucleotides) polyadenyl sequence at the 3'-end of F-PV RNA. A polyadenyl sequence is missing at the 3'end of WCMV RNA. A study of the translation products of WCMV and F-PV RNAs in a oe11-free protein-synthesizing system derived from rabbit reticulocytes showed that polypeptides electrophoretically comigrating with a structural protein of either virus were synthesized alongside high-molecular-weight polypeptides (M\(_r\)\(\approx\) 180-150 kdaltons).}, language = {en} } @article{RubtsovOganessyanGorboulevetal.1988, author = {Rubtsov, P. M. and Oganessyan, R. G. and Gorboulev, Valentin G. and Skryabin, K. G. and Bayev, A. A.}, title = {Genetic engineering of peptide hormones : II. Possible polymorphism of preprolactin in cattle. Data of molecular cloning}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46975}, year = {1988}, abstract = {Primary structure is determined of an insertion of a clone isolated from the library of hypophyseal cDNA of cattle by hybridization with a probe specific for prolactin. Analysis of nucleotide sequences showed that in the process of cloning, reorganization occurred in structure of preprolactin cDNA, including an inversion of the 5'-terminal and deletion of the central section of cDNA. Nevertheless, from structure of cDNA, nucleotide sequences can be deduced of extended 5'- and 3'-terminal sections of preprolactin mRNA in cattle with lengths of 257 and 551 nucleotide residues, respectively. When these sequences are compared to those established previously, some differences were found in primary structure. The most important of them is the presence of an additional codon which codes alanine at the position (-22) of the signal peptide. It is suggested that heterogeneity of preprolactin mRNA of cattle in the section coding the signal peptide is the result of alternative splicing, as was shown for preprolactin mRNA in rats.}, language = {en} } @article{RubtsovChernovGorboulevetal.1985, author = {Rubtsov, P. M. and Chernov, V. G. and Gorboulev, Valentin G. and Parsadanyan, A. S. and Sverdlova, P. S. and Chupeeva, V. V. and Golova, Yu. B. and Batchikova, N. V. and Zvirblis, G. S. and Skryabin, K. G. and Bayev, A. A.}, title = {Genetic engineering of peptide hormones}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46964}, year = {1985}, abstract = {Peptide and polypeptide hormones represent an extensive group of biologically active compounds of important significance for medicine and agriculture. In recent years genetic engineering methods have been used to create strains of microorganisms synthesizing eukaryotic proteins, including hormones and their precursors. The first stage of such developments is the isolation of DNA coding the des~red product. We have accomplished the cloning of the cDNA of a number of polypeptide and peptide hormones of the pituitary of man and domestic animals. The model gene of human calcitonin has also been synthesized and cloned. The obtained genes are being used to develop methods for the microbiological synthesis of human and animal-hormones.}, language = {en} } @article{ZvirblisGorboulevRubtsovetal.1988, author = {Zvirblis, G. S. and Gorboulev, Valentin G. and Rubtsov, P. M. and Chernov, B. K. and Golova, Yu. B. and Pozmogova, G. E. and Skryabin, K. G. and Bayev, A. A.}, title = {Genetic engineering of peptide hormones : III. Cloning of cDNA of porcine growth hormone and construction of gene for expression of hormone in bacteria}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46958}, year = {1988}, abstract = {Results are presented of cloning cDNA of procine growth hormone, analysis of its primary structure, and creation of a construction capable of expression of this cDNA in Esqheriahia coti cells. It is shown that in the population of mRNA coding porcine growth hormone, heterogeneity is noted which is manifested not only at the level of the nucleotide sequence, but also is reflected in the amino acid sequence of the mature hormone.}, language = {en} } @article{TsfasmanNesmeyanovaGorboulevetal.1989, author = {Tsfasman, I. M. and Nesmeyanova, M. A. and Gorboulev, Valentin G. and Rubtsov, P. M. and Skryabin, K. G.}, title = {Biosynthesis and secretion of bovine growth hormone in Escherichia coli under the control of the secretory vector containing a promoter and signal sequence of alkaline phosphatase gene}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46932}, year = {1989}, abstract = {A recombinant plasmid was constructed containing the gene for bovine growth hormone joinea with the regulatory region and the region coding the signal sequence of the Escherichia coli alkaline phosphatase gene. In conditions of phosphorus starvation, which c~s derepression of alkaline phosphatase, expression was shown of the gene for bovine growth hormone, in addition to partial processing and secretion of protein into periplasm.}, language = {en} } @article{KauppZyubinCharkinetal.1993, author = {Kaupp, Martin and Zyubin, A. S. and Charkin, O. P. and Schleyer, P. v. R}, title = {Non-Empirical Calculation of the Structure and Stability of Borohydrides of Zinc, Cadmium and Mercury of the Types MBH4 and HMBH4}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46339}, year = {1993}, abstract = {No abstract available}, language = {ru} } @article{HommersSteller1977, author = {Hommers, Wilfried and Steller, Max}, title = {Zur Behandlungsmotivation von Delinquenten : Empirische Befunde zu Leidensdruck und anderen motivationalen Variablen als sozialtherapeutische Eignungskriterien}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47088}, year = {1977}, abstract = {In dieser Untersuchung sollte empirisch gepr{\"u}ft werden, welche motivationalen Voraussetzungen f{\"u}r Psychotherapie bei inhaftierten Delinquenten vorliegen. Die Untersuchungsmethode bestand in der Auswahl zutreffender Selbstbeschreibungen aus "Problem-Items", zu denen anschließend Zusatzfragen hinsichtlich der Auspr{\"a}gung von f{\"u}nf motivationalen Variablen (Leidensdruck, Unzufriedenheit, {\"A}nderungswtinsch, Hilfewunsch und Erfolgserwartung) beantwortet werden mußten. 211 m{\"a}nnliche jugendliche Inhaftierte wurden mit 207 Berufssch{\"u}lern verglichen. Durch konfigurale Klassifikation wurde gepr{\"u}ft, ob sie bestimmten Therapiemotivations-Syndromen (TMS) zugeordnet werden konnten. Es zeigte sich, daß nur zuf{\"a}llig viele Berufssch{\"u}ler, aber signifikant viele Delinquente in folgende TMS-Gruppen klassifiziert werden konnten: Leidensdruck/{\"A}nderungswunsch und Unzufriedenheit Hilfewunsch jeweils mit hoher bzw. geringer Erfolgserwartung. Delinquente mit g{\"u}nstigen motivationalen Voraussetzungen f{\"u}r Psychotherapie (Leidensdruck/{\"A}nderungswunsch) wiesen k{\"u}rzere Inhaftierungszeiten auf als die Unzufriedenheit-/Hilfewunschgruppe. Mit Hilfe des vorgestellten diagnostischen Verfahrens k{\"o}nnen therapeutische Zwischen ziele f{\"u}r behandlungsbed{\"u}rftige Delinquente mit ung{\"u}nstigen motivationalen Voraussetzungen formuliert werden.}, language = {de} } @article{KerkauSchmittLandgrafSchimpletal.1989, author = {Kerkau, Thomas and Schmitt-Landgraf, Renate and Schimpl, Anneliese and Wecker, Eberhard}, title = {Downregulation of HLA Class I Antigensin HIV-1-Infected Cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47172}, year = {1989}, abstract = {By means of indirect immunofluorescence analysis we investigated the effect of HIV -1 infection on HLA class I surface antigens. We report here that in CD4\(^+\) HeLa cells, in H9 cells, and in peripheral T Iymphocytes HLA class I antigens are down regulated following infection with HIV -1. The downregulation is effected at a posttranscriptional level since the amounts of HLA class I specific mRNA are similar in infected and uninfected cells. This phenomenon is not only correlated with the state of infection, that is, the presence of P24 of HIV-l in the cells, but also depends on the time of infection. Upon HLA class I downregulation by HIV infection, the specific lysis of peripheral blood cells by allogeneic CTL is reduced.}, language = {en} } @article{BoriskinDesyatskovaBogomolovaetal.1986, author = {Boriskin, Yu S. and Desyatskova, R. G. and Bogomolova, N. N. and Gorboulev, Valentin G.}, title = {Stability of rubella virus after long-term persistence in human cell line}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46944}, year = {1986}, abstract = {Primary infection of HEp-2 cells with rubella virus resulted in non-cytophatic longterm persistent infection. During four years of persistence the virus was produced in sufficient quantities (up to 6 logs PFU/ml) and did not differ from the parental variant in its pathogenicity for BHK-21 or RK-13 cells, or hemagglutinating activity, but formed smaller plaques. Persistent virus preserved the original antigenicity as judged from reciprocal hemagglutination-inhibition or plaque reduction-neutralization tests with polyclonal antisera. Both original and persistent rubella viruses were thermoresistant (T 56° C) and sligthly temperature-sensitive. Clonal analysis revealed presence of ts-mutants among both original and persistent virus clones with different degrees of plating efficiency at 40°/34° C. RNA fingerprinting showed only minor changes in persistent rubella virus.}, language = {en} } @article{WernerWernerBurschka1984, author = {Werner, Helmut and Werner, Reiner and Burschka, Christian}, title = {Aromaten(phosphan)metall-Komplexe, V: zur Addition von Carbanionen an (Benzol)ruthenium(II)- und -osmium(II)-Komplexe. Kristall- und Molek{\"u}lstruktur von (exo-6-n-C4H9-Pi5-C6H6)OsI(PMe3)2}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46652}, year = {1984}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{SchenkKhadraBurschka1990, author = {Schenk, Wolfdieter A. and Khadra, Almuetassem and Burschka, Christian}, title = {Schwefel(IV)-Verbindungen als Liganden: XII. Ring{\"o}ffnung von Thiiran-1-oxid, Struktur des intermedi{\"a}ren Lewis-S{\"a}ure-Addukts}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46641}, year = {1990}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{BringmannHartungGoebeletal.1992, author = {Bringmann, Gerhard and Hartung, Thomas and Goebel, Lothar and Schupp, Olaf and Ewers, Christian L. J. and Schoener, Bernd and Zagst, Rainer and Peters, Karl and Von Schnering, Hans Georg and Burschka, Christian}, title = {Novel concepts in directed biaryl synthesis, IX: Synthesis and structure of benzonaphthopyranones, useful bridged model precursors for stereoselective biaryl syntheses}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46635}, year = {1992}, abstract = {A practicable two-step procedure for the preparation of a series of lactone-type bridged biaryls 7 as favorable substrates for subsequent atropisomer-selective ring-opening reactions is described. Due to the efficiency of the coupling step, which tolerates even a telt·butyl group next to the biaryl axis and avoids problems of regioselectivity, a variety of differently substituted representatives is prepared. These cover a broad range of steric hindrance and thus molecular distortion. The structures are investigated mainly by NMR spectroscopy and X-ray diffraction, showing the lactones 7 to be helically distorted, depending on the size of the residues R.}, subject = {Chemie}, language = {en} } @article{WernerKletzinBurschka1984, author = {Werner, H. and Kletzin, H. and Burschka, Christian}, title = {Aromaten(Phosphan)Metall-Komplexe: VIII. Syntese und Struktur eines Diaromatenruthenium-Komplexes mit Pi-gebundenem Triphenylphosphan-Liganden}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46627}, year = {1984}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{HoffmannBurschka1984, author = {Hoffmann, Gerhard G. and Burschka, Christian}, title = {Darstellung und Eigenschaften von Diphenylalkylthio- und Diphenylarylthio-Gallanen : Kristallstruktur von Diphenylethylthiogallan}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46612}, year = {1984}, abstract = {Triphenylgallan reagiert mit Alkyl- bzw. Arylthiolen unter Bildung der entsprechenden Diphenylalkyl- und Diphenylarylthiogallane. Spektren sowie einige physikalische und chemische Eigenschaften der neuen Verbindungen werden mitgeteilt. Die Ergebnisse der R{\"o}ntgenstrukturuntersuchung von Diphenylethylthiogallan werden diskutiert.}, subject = {Chemie}, language = {de} } @article{EyckBurschkaBronger1973, author = {Eyck, J. and Burschka, Christian and Bronger, W.}, title = {Neue tern{\"a}re Sulfide des Silbers}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46606}, year = {1973}, abstract = {No abstract available}, language = {de} } @article{WernerHeiserBurschka1982, author = {Werner, Helmut and Heiser, Bernd and Burschka, Christian}, title = {Cycloadditionsreaktionen von Organometallkomplexen, I: die Synthese viergliedriger Metalla-Heterocyclen durch [2 + 2]-Cycloaddition aus (Isonitril)cobalt-Komplexen und Isocyanaten sowie Isothiocyanaten}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46589}, year = {1982}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{SchmidtBenderBurschka1979, author = {Schmidt, M. and Bender, R. and Burschka, Christian}, title = {Additionsverbindungen zwischen Antimon(III)-Halogeniden und 1,4-Dithiacycloheptan}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46570}, year = {1979}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{BrongerBurschka1976, author = {Bronger, W. and Burschka, Christian}, title = {K\(_2\)Ag\(_4\)S\(_3\) und Rb\(_2\)Ag\(_4\)S\(_3\) : Synthese und Struktur}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46569}, year = {1976}, abstract = {Durch Umsetzungen von Alkalimetallcarbonaten mit Silber und Schwefel in der Schmelze wurden die tern{\"a}ren Sulfide K2Ag4S3 und Rb2Ag4S3 dargestellt. R{\"o}ntgenographische Untersuchungen an Einkristallen f{\"u}hrten zu einem neuen Schichtenstrukturtyp, in dem r{\"o}hrenf{\"o}rmige Silber-Schwefel-Anordnungen mit nahezu trigonal planar von Schwefel koordinierten Silberatomen {\"u}ber gemeinsame S-Atome zu Schichten"verkn{\"u}pft werden, zwischen denen die Alkalimetallatome eingelagert sind. Die monoklinen Elementarzellen enthalten vier Formeleinheiten. Die h{\"o}chstsymmetrische Raumgruppe ist C2/m. Als Gitterkonstanten ergeben sich: K\(_2\)Ag\(_4\)S\(_3\): a = 17,36(1) A, b = 4,296(2) A, c = 11,603(5) A, B = 108,32(3t; Rb\(_2\)Ag\(_4\)S\(_3\): 80 = 17,88(1) A, b = 4,331(5) A, c = 11,849(5) A, B = 108,58(3)°.}, subject = {Chemie}, language = {de} } @article{BurschkaWieberRuedling1980, author = {Burschka, Christian and Wieber, M. and Ruedling, H. G.}, title = {Alkylxanthogenato-diphenylbismutine}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46554}, year = {1980}, abstract = {No abstract available}, subject = {Chemie}, language = {de} } @article{Hommers1994, author = {Hommers, Wilfried}, title = {Zur Einzelfalldiagnose der Wertungskompetenz bei fahrl{\"a}ssigen Brandstiftungen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43420}, year = {1994}, abstract = {In 2 Untersuchungen mit 100 bzw. 88 Minderj{\"a}hrigen und 60 Erwachsenen werden Geschichten {\"u}ber drei - eine versehentliche, eine fahrl{\"a}ssige, eine absichtliche - Brandstiftungen mit bildlicher Unterst{\"u}tzung dargeboten. Durch Paarvergleiche zwischen bzw. Sch{\"a}tzurteile {\"u}ber die Geschichten wird ausgehend von der Wertungskomponente der Deliktsf{\"a}higkeit die F{\"a}higkeit zur Unrechtserkenntnis f{\"u}r fahrl{\"a}ssige Sch{\"a}digungen im Sinne der moralischen Differenzierungsf{\"a}higkeit untersucht, um einerseits die technische Durchf{\"u}hrungsform und andererseits die einzelfalldiagnostische Auswertung nach psychometrischen bzw. varianzanalytischen Strategien zu erproben. Außerdem werden die Beziehungen der so erfaßten Wertungskomponenten zu Intelligenzuntertests gepr{\"u}ft. Aufgrund fehlender Korrelationen mit den Intelligenzmaßen empfiehlt sich die Anwendung des Verfahrens zur psychometrischen Begr{\"u}ndung von Diagnosen zur zivilrechtlichen Verantwortlichkeit im Sinne des \S 828 (2) BGB, damit sich die diesbez{\"u}glichen Diagnosen auch auf die Wertungskomponenten st{\"u}tzen k{\"o}nnen.}, subject = {Psychologische Diagnostik / Psychologie / Zeitschrift / Differentielle Psychologie}, language = {de} } @article{HommersSteller1977, author = {Hommers, Wilfried and Steller, Max}, title = {Zur Diagnose der Therapiemotivation durch konfigurale Klassifikation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43416}, year = {1977}, abstract = {Es wird ein konfigural-analytisches Verfahren zur Erfassung von f{\"u}nf Variablen der Therapiemotivation (Leidensdruck, Unzufriedenheit, {\"A}nderungswunsch, Hilfewunsch und Erfolgserwartung) beschrieben. Die Methode besteht aus einer Kombination der Auswahl zutreffender Selbstbeschreibungen ("Probleme") und der Beantwortung motivationsbezogener Zusatzfragen. Jeder Pb wird so zu seinen spezifischen Problemen hinsichtlich der Auspr{\"a}gung therapierelevanter motivationaler Variablen befragt. Aus der Beantwortung der Zusatzfragen k{\"o}nnen verschiedene Therapiemotivations- Syndrome (TMS) gebildet werden. Die statistische Absicherung des individuellen Vorkommens eines TMS in den Zusatzbefragungen erfolgt {\"u}ber die Multinominalverteilung. Dabei wird von der H{\"a}ufigkeit ausgew{\"a}hlter Probleme eines Pb abstrahiert. Die Erprobung des Verfahrens wurde an 211 Inhaftierten einer Jugendstrafanstalt als potentieller Klienten-Population vorgenommen. Als Kontrollgruppe dienten 207 Berufssch{\"u}ler vergleichbaren Alters. W{\"a}hrend bei den Berufssch{\"u}lern die H{\"a}ufigkeit bei der Klassifikation in verschiedene TMS-Gruppen immer im zuf{\"a}lligen Bereich lagen, konnten bei den Delinquenten {\"u}berzuf{\"a}llig h{\"a}ufig besetzte Gruppenst{\"a}rken gefunden werden. In der Diskussion wurde auf den Unterschied des hier benutzten Klassifikationsverfahrens zur Konfigurations-Frequenzanalyse und zu Maßen Externaler-Internaler-Kontrolle eingegangen. Außerdem wurden Implikationen der Diagnose von Klienten-Therapiemotivation ftir die Entwicklung therapeutischer Verfahren aufgezeigt.}, subject = {Psychologische Diagnostik / Psychologie / Differentielle Psychologie / Zeitschrift}, language = {de} } @article{Hommers1986, author = {Hommers, Wilfried}, title = {Zum Zusammenwirken von Schadensh{\"o}he und Ersatzausmaß im moralischen Urteil}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43404}, year = {1986}, abstract = {Das Zusammenwirken von Informationen {\"u}ber die Schadensh{\"o}he und die Ersatzleistung wurde untersucht hinsichtlich der Relation der Effekrst{\"a}rken und hinsichtlich der Additivit{\"a}t. 20 Erwachsene und 40 Kinder im Alter von 6 und 8 Jahren beurteilten auf einer Gut-B{\"o}se-Skala 12 Darstellungen von ruinierten Briefmarken und von einwandfreien Briefmarken, die der T{\"a}ter dem Gesch{\"a}digten als Wiedergutmachung gab. In den Ergebnissen war der Ersatz-Effekt bei Vor- und Grundsch{\"u}lern erheblich gr{\"o}ßer als der Schaden-Effekt. Erwachsene hatten einen geringeren Effekt der Ersatzleistung als Kinder. Weiterhin wirkten beide Informationen in allen Gruppen nicht additiv zusammen, so daß eine Resrschaden-Beurteilung als Urteilsprozeß widerlegt wurde.}, subject = {P{\"a}dagogische Psychologie / Zeitschrift / Entwicklungspsychologie}, language = {de} } @article{Hommers1975, author = {Hommers, Wilfried}, title = {Zur Abh{\"a}ngigkeit des Entscheidungsverhaltens lernbehinderter Sondersch{\"u}ler von der Vorerfahrung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44212}, year = {1975}, abstract = {Die Auswirkung einer Vorerfahrungsbedingung auf das Entscheidungsverhalten von Sch{\"u}lern wurde untersucht. 188 Volksund lernbehinderte Sondersch{\"u}ler im Alter von 8 bis 14 Jahren wurden 15mal vor die Entscheidung gestellt, eine von drei Alternativen zu w{\"a}hlen. Die Wahlalternativen waren "Spiele gegen die Natur" mit den Konsequenzen" reale Gewinnauszahlung" und" Ausbleiben des Gewinns" .Als Lernbedingung dienten Spiele, bei denen das negative Ergebnis in dem realen Verlust eines Geldbetrages bestand. Es zeigten sich ein Anstieg von LageWahlen mit dem Alter und eine f{\"o}rdernde Wirkung der Lernbedingungbei Sondersch{\"u}lern, die 12 Jahre alt oder {\"a}lter waren. Außerdem ließen die Daten die Vermutung zu, daß das Ausmaß der Retardierung lernbehinderter Sondersch{\"u}ler im Entscheidungsverhalten gr{\"o}ßer ist als in einem sprachfreien Intelligenztest.}, subject = {Sonderp{\"a}dagogik / Zeitschrift}, language = {de} } @article{HommersEndres1992, author = {Hommers, Wilfried and Endres, Johann}, title = {Strafzweckeinstellungen als Moderatorvariable in den Urteilsschemata von Strafe und Ersatz}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44192}, year = {1992}, abstract = {Die Beschreibung einer fahrl{\"a}ssigen K{\"o}rperverletzung im Straßenverkehr wurde mit 12 Stimulusgeschichten in den Informationen {\"u}ber die Entschuldigung des T{\"a}ters und die Drittentsch{\"a}digung des Opfers in einem faktoriellen Meßwiederholungsplan variiert. Abh{\"a}ngige Variablen waren jeweils verbundene Schadensersatz· und Strafurteile. Weiterhin wurden die Einstellungen der Pbn zu Aspekten von Vergeltung, Pr{\"a}vention, Resozialisierung und Wiedergutmachung mit 12 Items auf siebenstufigen Ratingskaien erfaßt. Die Wirkung der beiden Stimulusinformationen war urteilsabh{\"a}ngig. Aber ein Teil der 58 Pbn ber{\"u}cksichtigte die Entschuldigung nicht nur bei den Strafurteilen, sondern auch beim Schadensersatz. Da diese Pbn vor allem pr{\"a}ventiven Strafzwekken zustimmten, wurde die Hypothese einer pr{\"a}ventiven Verwendung des Schadensersatzes als Erkl{\"a}rung des Effekts der Entschuldigung auf dem Ersatz gest{\"u}tzt. Die konkurrierende Hypothese, wonach die Entschuldigung die immaterielle Wiedergutmachung des Schadensersatzes abdeckt, fand hingegen keine ausreichende Best{\"a}tigung. Die Fortentwicklung und Anwendung des verwendeten Instruments zur Erfassung von Einstellungen zu Sanktionszwecken erscheint sinnvoll.}, subject = {Angewandte Psychologie / Zeitschrift / Experimentelle Psychologie}, language = {de} } @article{Hommers1993, author = {Hommers, Wilfried}, title = {Zum Begriff der Rechtspsychologie unter professioneller Perspektive}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43383}, year = {1993}, abstract = {No abstract available}, language = {de} } @article{BonteTravisDeClercqetal.2008, author = {Bonte, Dries and Travis, Justin M. J. and De Clercq, Nele and Zwertvaegher, Ingrid and Lens, Luc}, title = {Thermal conditions during juvenile development affect adult dispersal in a spider}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-48691}, year = {2008}, abstract = {Abstract: Understanding the causes and consequences of dispersal is a prerequisite for the effective management of natural populations. Rather than treating dispersal as a fixed trait, it should be considered a plastic process that responds to both genetic and environmental conditions. Here, we consider how the ambient temperature experienced by juvenile Erigone atra, a spider inhabiting crop habitat, influences adult dispersal. This species exhibits 2 distinct forms of dispersal, ballooning (long distance) and rappelling (short distance). Using a half-sib design we raised individuals under 4 different temperature regimes and quantified the spiders' propensity to balloon and to rappel. Additionally, as an indicator of investment in settlement, we determined the size of the webs build by the spiders following dispersal. The optimal temperature regimes for reproduction and overall dispersal investment were 20 °C and 25 °C. Propensity to perform short-distance movements was lowest at 15 °C, whereas for long-distance dispersal it was lowest at 30 °C. Plasticity in dispersal was in the direction predicted on the basis of the risks associated with seasonal changes in habitat availability; long-distance ballooning occurred more frequently under cooler, spring-like conditions and short-distance rappelling under warmer, summer-like conditions. Based on these findings, we conclude that thermal conditions during development provide juvenile spiders with information about the environmental conditions they are likely to encounter as adults and that this information influences the spider's dispersal strategy. Climate change may result in suboptimal adult dispersal behavior, with potentially deleterious population level consequences.}, language = {en} } @article{GrosHovestadtPoethke2008, author = {Gros, Andreas and Hovestadt, Thomas and Poethke, Hans Joachim}, title = {Evolution of sex-biased dispersal : the role of sex-specific dispersal costs, demographic stochasticity, and inbreeding}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-48705}, year = {2008}, abstract = {Abstract: Inbreeding avoidance and asymmetric competition over resources have both been identified as factors favoring the evolution of sex-biased dispersal. It has also been recognized that sex-specific costs of dispersal would select for sex-biased dispersal, but there is little quantitative information on this aspect. In this paper we explore (i) the quantitative relationship between cost-asymmetry and a bias in dispersal, (ii) the influence of demographic stochasticity on this effect, and (iii) how inbreeding and cost-asymmetry interact in their effect on sex-specific dispersal. We adjust an existing analytical model to account for sex-specific costs of dispersal. Based on numerical calculations we predict a severe bias in dispersal already for small differences in dispersal costs. We corroborate these predictions in individual-based simulations, but show that demographic stochasticity generally leads to more balanced dispersal. In combination with inbreeding, cost asymmetries will usually determine which of the two sexes becomes the more dispersive.}, language = {en} } @article{GrosPoethkeHovestadt2009, author = {Gros, Andreas and Poethke, Hans Joachim and Hovestadt, Thomas}, title = {Sex-specific spatio-temporal variability in reproductive success promotes the evolution of sex-biased dispersal}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-48711}, year = {2009}, abstract = {Abstract: Inbreeding depression, asymmetries in costs or benefits of dispersal, and the mating system have been identified as potential factors underlying the evolution of sex-biased dispersal. We use individual-based simulations to explore how the mating system and demographic stochasticity influence the evolution of sex-specific dispersal in a metapopulation with females competing over breeding sites, and males over mating opportunities. Comparison of simulation results for random mating with those for a harem system (locally, a single male sires all offspring) reveal that even extreme variance in local male reproductive success (extreme male competition) does not induce male-biased dispersal. The latter evolves if the between-parch variance in reproductive success is larger for males than females. This can emerge due to demographic stochasticity if the habitat patches are small. More generally, members of a group of individuals experiencing higher spatio-temporal variance in fitness expectations may evolve to disperse with greater probability than others.}, language = {en} } @article{Hommers1986, author = {Hommers, Wilfried}, title = {Non-Additivit{\"a}t als Beleg f{\"u}r die moralische Natur der Integration von Schaden und Ersatz}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44188}, year = {1986}, abstract = {Beruhten non-additive Strukturen von Urteilen {\"u}ber Schadenswiedergutmachungen lediglich auf Verarbeitung "objektiver" Informationen oder schlossen sie "subjektive" Prozesse ein, die f{\"u}r eine besondere moralische Natur der Urteile sprachen? 60 Vorsch{\"u}ler, Grundsch{\"u}ler und Erwachsene beurteilten visuell dargebotene Kombinationen von Sachschadens- und Ersatzleistungsumf{\"a}ngen. Die Urteile wurden mit zwei Klassen von jeweils drei Prozeßmodellen verglichen. Die einen ber{\"u}cksichtigten objektiv wahrnehmbare Eigenschaften der Stimuli, die anderen waren Erscheinungsformen eines multiplikativen Integrationsgesetzes f{\"u}r Schadensumf{\"a}nge und f{\"u}r "subjektive" Werte der Ersatzproportionen. Das die Urteile jeweils einer Versuchsperson best-beschreibende Modell stammte in 90 \% der F{\"a}lle aus der Klasse der multiplikativen Integration. Die Kindergarten-Gruppe hatte homogenere Modell-Zuordnungen als die Grundsch{\"U}ler-Gruppe.}, language = {de} } @article{MollBoesingSchneider1988, author = {Moll, Heidrun and B{\"o}sing-Schneider, Rita}, title = {The transplantation barrier of nude mice}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46045}, year = {1988}, abstract = {Syngeneic memory cells can be stimulated to yield a secondary immune response after their transfer into irradiated euthymie recipients as well as into young thymusless nude mice. It is shown that nude mice older than twelve weeks of age are not permissive towards memory cell activation as it is found in non-irradiated euthymie animals. This barrier to isogeneie or congeneic cells seems to be caused by a pool of cyclophosphamide-sensitive cells. Since young nude mice could be rendered as unpermissive as older nude mice by pretreatment with either PNA-agglutinable thymus cells or nylon-wool passed spleen cells, it is suggested that an increased number of precursor T cells in older nude mice might induce this effect. Further experiments with monoclonal antibodies against the Lyt-l, Lyt-2, and L3T4 marker on T cells indicate that T -helper/inducer activity might be required to establish the "isogeneie barrief" in nude mice.}, language = {de} } @article{SolbachMollRoellinghoff1991, author = {Solbach, Werner and Moll, Heidrun and R{\"o}llinghoff, Martin}, title = {Lymphocytes play the music but the macrophage calls the tune}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45889}, year = {1991}, abstract = {No abstract available}, subject = {Immunologie}, language = {en} } @article{GillitzerMoll1993, author = {Gillitzer, Reinhard and Moll, Heidrun}, title = {Simultaneous demonstration of two antigens with immunogold-silver staining and immunoenzymatic labeling}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33019}, year = {1993}, abstract = {A novel technique for independent and simultaneous labeling of two antigens expressed on individual cells (referred to as mixed labeling) is presented. The staining procedure combined three-step (streptavidin-biotin) immunogold-silver staining with three-step immunoenzymatic labeling. To ensure both high specificity and high sensitivity, particular emphasis was placed on designing a protocol that avoids immunological crossreactivity between the antibody reagents and overlapping of the final color products. Two examples for usage of this mixed labeling technique are described: lymphocyte subpopulations were identified in inflammatory lesions of human skin and infected host cells were characterized in the skin of mice infected with the obligatory intracellular parasite Leishmania major, a cause of human cutaneous leishmaniasis.}, language = {en} }