@phdthesis{Wittek2003, author = {Wittek, Nina}, title = {Untersuchungen zur K{\"o}rperschemast{\"o}rung bei Anorexia nervosa}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-8018}, school = {Universit{\"a}t W{\"u}rzburg}, year = {2003}, abstract = {Die Arbeit befasst sich mit dem Symptomkomplex K{\"o}rperschemast{\"o}rung bei Patientinnen mit Anorexia nervosa. Verschiedene Messmethoden zur Erfassung von K{\"o}rperschemast{\"o}rung werden einander gegen{\"u}bergestellt. Die Arbeit analysiert mittels Computer Body Image Test das K{\"o}rperbild jugendlicher Anorexiepatientinnen. Dar{\"u}ber hinaus wird eine Abh{\"a}ngigkeit der K{\"o}rperschemast{\"o}rung von Therapieverlauf und Schweregrad der Erkrankung untersucht.}, language = {de} } @phdthesis{Schuler2003, author = {Schuler, Simone}, title = {Verlaufsuntersuchung zu Knochendichtever{\"a}nderungen bei juveniler Anorexia nervosa und Implikationen f{\"u}r ihre Therapie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-7511}, school = {Universit{\"a}t W{\"u}rzburg}, year = {2003}, abstract = {In der vorliegenden Arbeit konnten 52 von 103 Patientinnen, die in der Zeit von 1989 bis 1995 aufgrund einer Anorexia nervosa an der Universit{\"a}tsklinik f{\"u}r Kinder- und Jugendpsychiatrie W{\"u}rzburg station{\"a}r behandelt worden waren, nach im Mittel 5,3 Jahren pers{\"o}nlich nachuntersucht werden. Schwerpunkte der Studie waren der Langzeitverlauf der Knochendichte nach einer Erkrankung an Anorexia nervosa und m{\"o}gliche Einflussfaktoren auf die Knochendichteentwicklung. Es wurde untersucht, in wieweit sich Krankheitsverlauf, Heilungserfolg, {\"O}strogensubstitution, Amenorrhoedauer sowie sportliche Bet{\"a}tigung auf die Entwicklung der Knochendichteparameter auswirkten. Im Gegensatz zu den meisten vorhergehenden Verlaufsstudien wurde eine relativ große Patientinnengruppe, die alle im Kindes- und Jugendalter erkrankt waren und {\"u}ber Ausgangsdaten bez{\"u}glich der Knochendichte verf{\"u}gten, pers{\"o}nlich nachuntersucht. Neben verschiedenen klinischen Parametern wurde die Knochendichte mittels pQCT und DEXA bestimmt. Es zeigte sich, dass Knochendichteverluste noch ver{\"a}nderbar waren und die jungen Frauen teilweise eine g{\"u}nstige Knochendichteentwicklung aufwiesen. Positiv wirkte sich vor allem ein g{\"u}nstiger Heilungsverlauf aus. Im Gegensatz dazu fand sich bei Patientinnen mit chronischem Krankheitsverlauf eine sehr ung{\"u}nstige Knochendichteentwicklung. Nicht ganz so positiv stellt sich die Restitution der Knochenarchitektur dar. Insgesamt ließ sich kein eindeutiger Einfluss einer {\"O}strogensubstitution nachweisen. Positive Tendenzen waren bez{\"u}glich der Knochendichteentwicklung im Zusammenhang mit sportlicher Aktivit{\"a}t zu beobachten. Die Ergebnisse zeigen, dass eine z{\"u}gige und anhaltende Gesundung der Patientinnen den einzig nachweislich positiven Einflussfaktor auf die Knochendichteentwicklung darstellt. In wieweit die Einflussgr{\"o}ßen sportliche Aktivit{\"a}t und {\"O}strogensubstitution sich g{\"u}nstig auswirken, ließ sich nicht eindeutig kl{\"a}ren. Aus diesem Grund bedarf es weiterf{\"u}hrender prospektiver, randomisierter Studien, um die anorexieassoziierten Knochendichtever{\"a}nderungen und damit verkn{\"u}pfte Einflussfaktoren zu verstehen.}, language = {de} } @phdthesis{Schiffczyk2017, author = {Schiffczyk, Eva-Maria}, title = {„Katamnestische Untersuchung der Behandlungszufriedenheit kindlicher Patientinnen und Patienten mit Anorexia nervosa nach station{\"a}rem Klinikaufenthalt"}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-156165}, school = {Universit{\"a}t W{\"u}rzburg}, year = {2017}, abstract = {Summary The aims of the current "Catamnestic examination of treatment satisfaction of patients with anorexia nervosa (AN) in childhood after inpatient treatment" were to extend the low data on AN in childhood in general and treatment satisfaction of this patient group in particular, and to use the knowledge gained to optimize future treatment concepts for patients with AN in childhood. To the best of our knowledge this is the first study retrospectively describing the treatment satisfaction of a patient population consisting exclusively of patients with a former AN in childhood. The central questions of the study were to find out whether and how many patients retrospectively found the treatment to be "satisfactory / unsatisfactory" or "helpful / harmful" and which elements of inpatient therapy produced "satisfaction / dissatisfaction" or subjective "help / harm" through the therapy. Further important aims of the study were to find out whether there is a correlation between the "treatment satisfaction / help / treatment amount" and various patient- and therapy-related parameters. The recent catamnestic study shows that former patients with AN in childhood, as well as other groups of AN patients (children, adolescents, adults) in previous studies, appear to be critical about the medical treatment compared to patients with other mental illnesses, with only 55.8 \% of the total patients who were at least mediocrely satisfied showing rather moderate satisfaction rates in the context of closed questions. Most likely are also in patients with AN in childhood typical disease characteristics (e.g. ambivalence in recovery and treatment, fear of loss of control) and personality traits (e.g. rigidity) frequently observed in AN patients responsible for that. The majority of patients with AN in childhood (65.4 \%) considered the therapy to be helpful retrospectively, in accordance with retrospective evaluations of patients with AN (children, adolescents, adults) on treatment as predominantly helpful. As part of the therapy, socio-emotional therapy components such as one-to-one therapeutic sessions, contact with fellow patients and caregivers were of the utmost importance for the patients with AN in childhood. These treatment elements generated the most satisfaction and were considered by many to be the most helpful. The results are hypothesis-generating that childlike patients with AN seem to have a special care / support need in the context of social relationships during therapy. However, the central role of socio-emotional components in therapy has also been highlighted in many other treatment satisfaction studies with childlike / adolescent and adult AN patients, patients with eating disorders in general, child and adolescent psychiatric and general psychiatric patients and in scientific work about the help of therapy for AN patients of different age groups as well as for other patient groups. As part of the therapeutic relationship, the desire for close contact with the therapist (more one-to-one interviews) was expressed. In addition, some patients wanted a more personalized therapy. The therapeutic relationship also played a key role in comparative studies with childlike and adolescent AN patients and other groups of patients, with sufficient time and individualism in therapy being required by the patients. A certain degree of self-determination, a fixed caregiver, inclusion of the family in the therapy, group therapy, adequate feedback and sufficient follow-up care were also important for the patients in the context of treatment. Treatment elements aimed at overcoming eating disordered behavior and recovering from the disease were partly rated to be satisfactory and helpful, but partly unsatisfactory and unhelpful. The critical evaluation of restrictive therapy elements to overcome the symptoms of eating disorders and ambivalence of patients with regard to their willingness to recover, their motivation to change and the initiation and implementation of a treatment, which has been cited in some studies, is also expressed in a group of patients with AN in childhood. With regard to these essential therapeutic ingredients for the treatment of AN, it is probably the right dosage in the context of the therapy concept. A comprehensible correlation was found in the fact that the former childlike AN patients, who judged the treatment to be satisfactory, also perceived it as more helpful and vice versa. The assumption that socio-cultural comparison variables (age and BMI) correlate with treatment satisfaction could not be proven in the own study for the former childlike study collective. Due to very different previous study results, further research on the relationship between socio-demographic variables and patient satisfaction is necessary in order to be able to draw clearer conclusions in this regard. However, an assumed association between the perceived help of the therapy and patient- / therapy-related variables could be confirmed, as patients with higher discharge BMI found treatment to be more helpful retrospectively than those with lower values. From a retrospective patient's perspective, this confirms the currently valid therapeutic guideline for not discharging patients from inpatient treatment until they achieve a body weight appropriate for their age and height (DGPM 2011). In addition, the perceived help from treatment at the different university hospitals showed significant differences, presumably due to the different specialization of the facilities with regard to eating disorders, as previous study results suggest that the treatment in an eating disorder clinic is more helpful than in a non-specialized hospital. With regard to the assessment of the treatment amount, the present catamnestic study showed contradictory results in relation to the long-term (presence of an eating disorder at the time of the catamnestic examination) or short-term treatment result (BMI at discharge) of the former AN patients. On average, patients who rated the amount of treatment as too low reported a higher BMI at hospital discharge (better short-term treatment outcome) than those who judged the treatment amount to be too high. This means that patients with better treatment results in the short term would have wished to receive more treatment quantitatively in the retrospective, than those with worse results. However, in return, more frequently, patients who still had an eating disorder (worse long-term outcome) at the time of study wished to have more treatment quantitatively, than recovered subjects at the time of the study (better long-term outcome). On this basis, it can be hypothesized that the patient group with lower discharge BMI may have had less disease insight than the group with higher discharge BMI, thus less able to engage in therapy with less benefit from it as a result of a poorer treatment outcome. It can also be speculated that in the meantime patients with a still ongoing eating disorder at the time of catamnesis had sufficient insight into the disease and therefore would have wished for more treatment retrospectively. Another plausible result of the current study is that patients who rated the treatment as satisfactory / helpful would have wanted more treatment quantitatively and patients who rated the treatment as unsatisfactory / harmful also judging the treatment amount to be too high. In summary, it becomes clear from our own results that it is a particular challenge to provide a therapy for patients with AN that finds their acceptance and satisfaction (Gulliksen et al., 2012). Accordingly, it is important to refine existing therapies and provide treatments that are adapted to the needs of the patient population. This requires a systematic knowledge of what generates satisfaction and dissatisfaction in patients with AN (Gulliksen et al., 2012). To our knowledge, the present study is the first study on treatment satisfaction that examined exclusively patients with former AN in childhood as a patient collective. Therefore, the results could only be compared with study data from other groups of patients (general psychiatric, child and adolescent psychiatric, eating disorder, adult and adolescent or partly childlike AN patients). Further studies with patients with AN in childhood are useful and desirable to validate the results presented here and to draw practical conclusions for an individualized treatment that meets the needs of the young patients.}, subject = {Anorexia nervosa}, language = {de} } @article{KolarHammerleJenetzkyetal.2016, author = {Kolar, David R. and Hammerle, Florian and Jenetzky, Ekkehart and Huss, Michael and B{\"u}rger, Arne}, title = {Aversive tension in female adolescents with Anorexia Nervosa: a controlled ecological momentary assessment using smartphones}, series = {BMC Psychiatry}, volume = {16}, journal = {BMC Psychiatry}, number = {97}, doi = {10.1186/s12888-016-0807-8}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-164720}, year = {2016}, abstract = {Background Current models of Anorexia Nervosa (AN) emphasize the role of emotion regulation. Aversive tension, described as a state of intense arousal and negative valence, is considered to be a link between emotional events and disordered eating. Recent research focused only on adult patients, and mainly general emotion regulation traits were studied. However, the momentary occurrence of aversive tension, particularly in adolescents with AN, has not been previously studied. Method 20 female adolescents with AN in outpatient treatment and 20 healthy adolescents aged 12 to 19 years participated in an ecological momentary assessment using their smartphones. Current states of aversive tension and events were assessed hourly for two consecutive weekdays. Mean and maximum values of aversive tension were compared. Multilevel analyses were computed to test the influence of time and reported events on aversive tension. The effect of reported events on subsequent changes of aversive tension in patients with AN were additionally tested in a multilevel model. Results AN patients showed higher mean and maximum levels of aversive tension. In a multilevel model, reported food intake was associated with higher levels of aversive tension in the AN group, whereas reported school or sport-related events were not linked to specific states of aversive tension. After food intake, subsequent increases of aversive tension were diminished and decreases of aversive tension were induced in adolescents with AN. Conclusions Aversive tension may play a substantial role in the psychopathology of AN, particular in relation with food intake. Therefore, treatment should consider aversive tension as a possible intervening variable during refeeding. Our findings encourage further research on aversive tension and its link to disordered eating.}, language = {en} } @phdthesis{Calame2004, author = {Calame, Silke}, title = {Zusammenhang von Angst mit dem Schweregrad der Anorexia nervosa - Komorbidit{\"a}t am Beispiel einer klinischen Studie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-13830}, school = {Universit{\"a}t W{\"u}rzburg}, year = {2004}, abstract = {In der Literatur wird eine hohe Komorbidit{\"a}t zwischen Anorexia nervosa und Angstst{\"o}rungen beschrieben. Die Dissertation beinhaltet eine klinische Studie anhand von 29 anorektischen Patientinnen, in der der Zusammenhang zwischen der Auspr{\"a}gung der Angst und dem Schweregrad der Anorexia nervosa untersucht wurde. Als Testverfahren kamen zur Anwendung State-Trait-Angstinventar (Stai), Sozialphobie und -angstinventar f{\"u}r Kinder (SPAIK), Anorexia nervosa Inventar zur Selbstbeobachtung (ANIS), Fragebogen zum Eßverhalten (FEV), Eating Disorder Inventory (EDI) und Body Mass Index (BMI). Es zeigte sich eine deutliche Korrelation zwischen der Angst und der Auspr{\"a}gung der psychopathologischen Symptomatik der Eßst{\"o}rung. Ein vermuteter Zusammenhang zwischen niedrigem Ausgangs - BMI und hohem Angstniveau konnte nicht best{\"a}tigt werden.}, language = {de} }