@article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Isoelektronische Derivate des Sila-Clofenetamins und des Sila-Mebrophenhydramins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63574}, year = {1976}, abstract = {Isoelectronic derivatives (A and B) and a homolog (C) of the two sila-antihistamines sila-clofenetamine and silamebrophenhydramine were synthesized for the first time by the steps shown in scheme 1. They and their unknown precursors II-IV were characterized by their physical (Table 1) and chemical properties and their structures confinned by lH-NMR and rnass spectroscopy (Tables 2 and 3). The pharrnacological effects of A and B were investigated and compared with those of the corresponding 0-isosteric sila-antihistarnines (Chapter 5).}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Derivate des Sila-Mephenhydramins und Sila-Chlorphenoxamins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63562}, year = {1976}, abstract = {Derivatives A and B of the two sila-antihistam.ines silamephenhydramine and sila-chlorphenoxamine were synthesized for the first time by the steps shown in scheme 1. They and their precursors III and IV were characterized by their physical (Table 1) and chemical properties and their structures confirmed by NMR and mass spectroscopy (Tables 2 and 3). Their pharmacological effects were investigated and compared with those of the corresponding sila-antihistamines.}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Sila-Analogon des Cicloniumbromids}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63556}, year = {1976}, abstract = {Sila-Analogues B 2 and A 2 of the spasmolytic ciclonium bromide (B 1) respectively the corresponding free base A 1 were synthesized for the first time according to the reaction steps sho·wn in scheme 1, and they and their precursors I and II were characterized by ph;ysical (Table 1} and chemical properties and their structures confirmed by NMR, and mass spectroscopy (Tables 2 and 3}. The pharmacological effects of A 2 and B 2 were investigated and compared with those of the parent carbon compound B 1 (chapter 5).}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Sila-Analoga des Mebrophenhydramins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63542}, year = {1976}, abstract = {Sila-analogues A 2, B 2 and C 2 of the drug mebrophenhydramine from the class of benzhydryl ethers -were synthesized for the first time by the steps shown in scheme 1, and they and their precurso:rs I-Ill were characterized by their physical (Table 1) and chemical properties, a.nd their structures confirmed by NMR, mass and infrared spectroscopy (Tables 3-5). The histaminolytic and anticholinergic effects of A 2 and C 2 were investigated and compared with some structure-activity relationships of analogue carbon compounds.}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Sila-Analoga des Chlorphenoxamins und des Clofenetamins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63531}, year = {1976}, abstract = {Sila-ana.logues A 2 and B 2 of two drugs from the benzhydryl ether class, chlorphenoxamine and clofenetamine, were synthesized for the first time by the steps shown in scheme 1. They and their precursors I-VI v;rere characterized by their physical (Table 1) and chemical properties and their structures confirmed by n.m.r., mass and infrared spectroscopy (Tab]es 2-5). Their physiological effects were invest.igated and compared with those of the carbon analogues (Chapter 5).}, subject = {Anorganische Chemie}, language = {de} }