@article{PfeifferRochlitzNoelkeetal.1990,
  author    = {Pfeiffer, A. and Rochlitz, H. and Noelke, B. and Tacke, R. and Moser, U. and Mutschler, E. and Lambrecht, G.},
  title     = {Muscarinic receptors mediating acid secretion in isolated rat gastric parietal cells are of M3 type},
  series = {Gastroenterology},
  volume    = {98},
  journal   = {Gastroenterology},
  number    = {1},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-128337},
  pages     = {218-222},
  year      = {1990},
  abstract  = {Five subtypes of muscarinic receptors have been identified by pharmacological and molecular biological methods. The muscarinic receptor subtype mediating acid secretion at the level of the parietal cell was unknown. Therefore, this study was performed to characterize muscarinic receptors on rat gastric parietal cells using the 3 subtype-selective antagonists hexahydrosiladifenidol and silahexocyclium, which have high affinity for glandular M3 subtypes, and AF-DX 116, which has high affinity to cardiac M2 receptors. The affinity of these antagonists was determined by radioligand binding experiments. In addition, their inhibitory potency on carbachol-stimulated inositol phosphate production was investigated. Inhibition of carbachol-stimulated aminopyrine uptake was used as an indirect measure of proton production. Both M3 antagonists, hexahydrosiladifenidol and silahexocyclium, had nanomolar affinities for parietal cell muscarinic receptors and potently antagonized inositol phosphate production with nanomolar Ki values. Silahexocyclium similarly antagonized aminopyrine accumulation while hexahydrosiladifenidol behaved as a noncompetitive antagonist. AF-DX 116 was a low-affinity ligand and a weak competitive antagonist at parietal-cell muscarinic receptors. It was concluded that muscarinic M3 receptors mediate acid secretion probably by activation of the phosphoinositide second messenger system in rat gastric parietal cells.},
  language  = {en}
}
@article{PfeifferHanackKoppetal.1990,
  author    = {Pfeiffer, A. and Hanack, C. and Kopp, R. and Tacke, R. and Moser, U. and Mutschler, E. and Lambrecht, G. and Herawi, M.},
  title     = {Human Gastric Mucosa Expresses Glandular M3 Subtype of Muscarinic Receptors},
  series = {Digestive Diseases and Sciences},
  volume    = {35},
  journal   = {Digestive Diseases and Sciences},
  number    = {12},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-128286},
  pages     = {1468-1472},
  year      = {1990},
  abstract  = {Five subtypes of muscarinic receptors have been distinguished by pharmacological and molecular biological methods. This report characterizes the muscarinic subtype present in human gastric mucosa by radioligand binding studies. The receptor density was 27 ± 6 fmol/mg protein and the tritiated ligand N-methylscopolamine had an affinity of (Kn) 0.39 ± 0.08 nM (n = 11). The M1 receptor selective antagonist pirenzepine and the M2 receptor selective ligand AF-DX 116 had low affinities of 148 ± 32 nM (n = 13) and 4043 ± 1011 nM (n = 3) K n , respectively. The glandular M3 antagonists hexahydrosiladifenidol and silahexocyclium had high affinities ofKn 78 ± 23 nM (n = 5) and 5.6 ± 1.8 nM (n = 3). The agonist carbachol interacted with a single low-affinity site and binding was insensitive to modulation by guanine nucleotides. Antagonist and agonist binding studies thus showed an affinity profile typical of M3 receptors of the glandular type.},
  language  = {en}
}
@article{Wilhelm1990,
  author    = {Wilhelm, Gernot},
  title     = {"Verhafte ihn!"},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72383},
  year      = {1990},
  abstract  = {No abstract available.},
  subject      = {Alter Orient},
  language  = {de}
}
@article{vonGehlenMatthesOkruschetal.1990,
  author    = {von Gehlen, K. and Matthes, S. and Okrusch, Martin and Richter, P. and R{\"o}hr, C. and Sch{\"u}ssler, Ulrich},
  title     = {Metapyroxenite in der KTB-Vorbohrung},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-87539},
  year      = {1990},
  abstract  = {No abstract available.},
  subject      = {Kontinentales Tiefbohrprogramm der Bundesrepublik Deutschland},
  language  = {de}
}
@article{Sponholz1990,
  author    = {Sponholz, Barbara},
  title     = {Silicate karst in eastern Niger - a geomorphological study},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86846},
  year      = {1990},
  abstract  = {No abstract available.},
  subject      = {Niger <Ost>},
  language  = {en}
}
@article{SchulzJosephBaumhaueretal.1990,
  author    = {Schulz, Erhard and Joseph, Alain and Baumhauer, Roland and Schultze, Ekkerhard and Sponholz, Barbara},
  title     = {Upper Pleistocene and Holocene history of the Bilma region (Kawar, NE-Niger)},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86828},
  year      = {1990},
  abstract  = {A 42 m drilling was pertormed in the depresalon of Bilma, Xawar, NE-Niger. The sediment and pollen records show that after an initial deposition of dune sands there were repeated lake phases which terminated by desiccation and consolidation of spring mounds. The pollen record indicates a continuous presence of savanna vegetation. The record probably covers the period between the Upper Pleistocene and the Late Holocene. The climate was characterised by a monssonal summer rain regime giving effective rain fall of about 450-500 mm per year. Groundwater recharge was possible but estimates of the amount of water resources are difficult because of the karstic system of the escarpment and the nearly unknown hydrogeological situation.},
  subject      = {Pleistoz{\"a}n},
  language  = {en}
}
@article{Wilhelm1990,
  author    = {Wilhelm, Gernot},
  title     = {Zur babylonisch-assyrischen Schultradition in Ḫattuša},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86457},
  year      = {1990},
  abstract  = {no Abstract available},
  subject      = {Boğazkale},
  language  = {de}
}
@article{BarnekowJahnSchartl1990,
  author    = {Barnekow, Angelika and Jahn, Reinhard and Schartl, Manfred},
  title     = {Synaptophysin: a substrate for the protein tyrosine kinase pp60c-src in intact synaptic vesicles},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86168},
  year      = {1990},
  abstract  = {Expression of pp60 c-src, the first well defined proto-oncogene product, is developmentally regulated and tissue-specific, with neuronal tissues displaying high amounts of the c-src encoded pp60 c-src kinase activity. In the central nervous system pp60 s-src is preferentially expressed in regions characterized by a high content of grey matter and elevated density of nerve terminals. In this study we show for the first time a direct interaction between pp60 c-src and synaptophysin as a physiological target protein in neurons by demonstrating that endogenous pp60 c-src is able to phosphorylate synaptophysin (p38). p38 is a major constituent of the synaptic vesicle membrane protein and is thought to play a key role in the exocytosis of small synaptic vesicles and possibly small clear vesicles in neuroendocrine cells.},
  subject      = {Synaptophysin},
  language  = {en}
}
@article{OpwisGoldGruberetal.1990,
  author    = {Opwis, Klaus and Gold, Andreas and Gruber, Hans and Schneider, Wolfgang},
  title     = {Zum Einfluß von Expertise auf Ged{\"a}chtnisleistungen sowie deren Selbsteinsch{\"a}tzung bei Kindern und Erwachsenen},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86565},
  year      = {1990},
  abstract  = {Junge und erwachsene Schachexperten und -novizen wurden bez{\"u}glich ihrer Behaltensleistungen f{\"u}r kurzzeitig dargebotene Schachstellungen und f{\"u}r Anordnungen geometrischer K{\"o}rper miteinander verglichen. Die Ergebnisse zeigen eine differenzierte Wirksamkeit von Expertise in Abh{\"a}ngigkeit von der Vertrautheit mit dem zu Lernenden Material und von der Art der Aufgabenstellung. Je vorwissensbezogener das zu Lernende Material ist, desto deutlicher ist der Einfluß von Expertise auf Ged{\"a}chtnisleistungen nachweisbar. Dies gilt in gleicher Weise f{\"u}r unmittelbare wie f{\"u}r l{\"a}ngerfristige Behaltensleistungen und f{\"u}r den Lernfortschritt. Im Unterschied dazu zeigt sich weder bei der Vorhersage eigener k{\"u}nftiger noch bei der Bewertung erbrachter Ged{\"a}chtnisleistungen ein systematischer Einfluß von Expertise.},
  subject      = {Ged{\"a}chtnisleistung},
  language  = {de}
}
@article{SchneiderUhl1990,
  author    = {Schneider, Wolfgang and Uhl, Christhild},
  title     = {Metaged{\"a}chtnis, Strategienutzung und Ged{\"a}chtnisleistung: Vergleichende Analysen bei Kindern, j{\"u}ngeren Erwachsenen und alten Menschen},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-69418},
  year      = {1990},
  abstract  = {Am Beispiel einer semantischen Kategorisierungsaufgabe (sort-recall task) wurde der Frage nachgegangen, in welchen Bestimmungsgr{\"o}ßen sich die Ged{\"a}chtnisleistungen von Schulkindern, j{\"u}ngeren sowie {\"a}lteren Erwachsenen voneinander unterscheiden. Es wurde angenommen, daß f{\"u}r diese drei Altersgruppen Ged{\"a}chtnisleistungen bei dieser Aufgabe in unterschiedlicher Weise durch Strategie- und Wissensaspekte bestimmt sind. Die im Vergleich zu Schulkindern und {\"a}lteren Erwachsenen {\"u}blicherweise besseren Leistungen j{\"u}ngerer Erwachsener sollten demnach im wesentlichen auf die konsequentere Nutzung von Ged{\"a}chtnisstrategien r{\"u}ckf{\"u}hrbar sein. Erwartet wurde weiterhin, daß die bei Schulkindern und {\"a}lteren Erwachsenen oft vorfindbaren "Produktionsdefizite" in der Strategienutzung unterschiedliche Ursachen haben : fehlt es bei den Sch{\"u}lern am notwendigen Ged{\"a}chtniswissen (Metaged{\"a}chtnis), so sind die Defizite der {\"a}lteren Menschen vorwiegend auf die mangelnde Erfahrung mit der Aufgabe zur{\"u}ckzuf{\"u}hren. Diese Annahmen wurden in einer Studie mit je 24 Probanden aus den drei genannten Altersgruppen {\"u}berpr{\"u}ft. W{\"a}hrend sich das erwartete Produktionsdefizit bei den Kindern auf unzureichendes Metaged{\"a}chtnis zur{\"u}ckf{\"u}hren ließ, gab es wenig Anhaltspunkte daf{\"u}r, daß das Strategiedefizit {\"a}lterer Menschen in wesentlichen auf mangelnde Aufgabenerfahrung r{\"u}ckf{\"u}hrbar ist. Leistungsunterschiede zwischen j{\"u}ngeren und {\"a}lteren Erwachsenen beruhen nicht auf unterschiedlichem Ged{\"a}chtniswissen, sondern d{\"u}rften auf dem kombinierten Einfluß von Strategie- und Kapazit{\"a}tsdefiziten basieren.},
  subject      = {Metaged{\"a}chtnis},
  language  = {de}
}
@article{SchartlNandaSchluppetal.1990,
  author    = {Schartl, Manfred and Nanda, Indrajit and Schlupp, Ingo and Parzefall, Jakob and Schmid, Michael and Epplen, J{\"o}rg T.},
  title     = {Genetic variation in the clonal vertebrate Poecilia formosa is limited to few truly hypervariable loci},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86359},
  year      = {1990},
  abstract  = {No abstract available.},
  subject      = {Amazon Molly},
  language  = {en}
}
@article{Krueger1990,
  author    = {Kr{\"u}ger, Hans-Peter},
  title     = {0.5 statt 0.8 Promille - Warum eigentlich? Neue Argumente f{\"u}r eine alte Forderung},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86218},
  year      = {1990},
  abstract  = {No abstract available},
  subject      = {Promillegrenze},
  language  = {de}
}
@article{WilkenKlotzTawfikSchlieperetal.1990,
  author    = {Wilken, Anke and Klotz, Karl-Norbert and Tawfik-Schlieper, Hoda and Schwabe, Ulrich},
  title     = {Pharmacological characterization of the adenylate cyclase-coupled adenosine receptor in isolated guinea pig atrial myocytes},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86061},
  year      = {1990},
  abstract  = {No abstract available.},
  subject      = {Pharmakologie},
  language  = {en}
}
@article{SchartlSchartl1990,
  author    = {Schartl, Angelika and Schartl, Manfred},
  title     = {Genes and cancer: Molecular biology of the melanoma oncogene of Xiphophorus},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72670},
  year      = {1990},
  abstract  = {No abstract available.},
  subject      = {Schwertk{\"a}rpfling},
  language  = {en}
}
@article{SchuesslerOkruschPatzaketal.1990,
  author    = {Sch{\"u}ssler, Ulrich and Okrusch, M. and Patzak, M. and M{\"u}ller, P. and Kreuzer, H.},
  title     = {The polyphase thermal history of the Erbendorf-Vohenstrauß (ZEV) and the Erbendorf Greenschist (EGZ) zones of NE Bavaria in the light of Ar-Ar spectra},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-81862},
  year      = {1990},
  abstract  = {no abstract available},
  subject      = {Erbendorf},
  language  = {en}
}
@article{SchuesslerSkinnerRoland1990,
  author    = {Sch{\"u}ssler, Ulrich and Skinner, D. N. B. and Roland, N.},
  title     = {Basischer bis intermedi{\"a}rer Plutonismus im NW-Teil des Wilson Terrane, Nordvictorialand, Antarktis},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-81850},
  year      = {1990},
  abstract  = {no abstract available},
  subject      = {Wilson Terrane},
  language  = {de}
}
@article{Lutz1990,
  author    = {Lutz, Werner K.},
  title     = {Dosis-Wirkungs-Beziehungen in der chemischen Kanzerogenese},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-80046},
  year      = {1990},
  abstract  = {Ich habe versucht darzulegen, daß mechanistische {\"U}berlegungen zur Extrapolation der Dosis-WirkungsBeziehung herangezogen werden k{\"o}nnen. Ein nichtlinearer Verlauf ist nicht nur bei den epigenetischen Kanzerogenen wahrscheinlich, sondern auch bei den DNA-bindenden. Echte Schwellen sind aber nur in solchen F{\"a}llen zu erwarten, wo kein endogenes Korrelat besteht. Immerhin k{\"o}nnen auch steile Nichtlinearit{\"a}ten zu einer drastischen Risikoreduktion f{\"u}hren, so daß die Anstrengungen dahin gehen sollten, die Steigung und den Bereich des {\"u}berproportionalen Abfalls experimentell zu zeigen. In einer heterogenen Population kann die 0 0- sis-Wirkungs-Kurve zus{\"a}tzliche "Wellen" bekommen und wird dadurch grunds{\"a}tzlich flacher. Im Extremfall ergibt sich eine lineare Dosis-Wirkungs-Beziehung unabh{\"a}ngig vom Wirkmechanismus des Kanzerogens. Diese Proportionalit{\"a}t zwischen tiefster Dosis und Effekt wird bei genotoxischen Kanzerogenen aus mechanistischen Gr{\"u}nden schon f{\"u}r eine homogene Population postuliert, doch kann dies in einer heterogenen Population auch bei epigenetischen Kanzerogenen in Frage kommen.},
  subject      = {Toxikologie},
  language  = {de}
}
@article{Linsenmair1990,
  author    = {Linsenmair, Karl Eduard},
  title     = {Tropische Biodiversitat: Befunde und offene Probleme},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-78302},
  year      = {1990},
  abstract  = {During the past 50 to over 100 million years communities evolved in the tropics which attained unprecedented levels of biodiversity, strikingly represented by evergreen lowland rain forests offering home to more than 50\% of all the world's extant species. Within only some 30 years human action reduced the area covered with tropical rain forests to about half of its former size, thereby negatively affecting local and global functions of the biosphere and exterminating an unknown number of species. With an exponentially increasing rate we are throwing away our and all future generations' biological heritage. We destroy the most complicated, scientifically most interesting living systems before we have gained any knowledge of their structures ,and dynamics. To understand the particular structures and dynamics of tropical communities means in the first place to understand the causes and consequences of their ten- to more than hundredfold higher alphadiversity (as compared to temperate systems). This problem has a historical dimension and a functional side requiring answers as to the nature of the proximate mechanisms of its maintenance. My review is only concerned with the latter aspect, and its maIn emphasis is on the gaps in our knowledge. Two sets of hypotheses have been developed for explaining the high within-commUnIty diversity. (1) According to the classical concept interspecific niche competition and subsequent niche separation are the main forces determining the structure of the community. These so-called equilibrium models have been contrasted in recent times with (2) non-equilibrium models. These models do not attribute the decisive role to interspecific competition. Strong niche overlaps are presumed to be very common within species-rich communities. Continuous stochastic local disturbances are assumed to prevent the achievement of any long-term equilibrium (climax) state. Being on the right spot at the right time is regarded as most important. Whether oneor a combination of both models provide the best key for understanding the structure of a special section within a community will certainly depend on many properties of the species at debate (mobility, disr.ersal, fertility etc.). For the vast majority of tropical organisms all such information is at present unavailable. The principles governing the structure of communities is just one of the very ,basic open problems. Another very prominent question is how the qualitatively very rich, however quantitatively poor resources are distributed among the members of highly diverse guilds of consumers and decomposers. Does the scarcity rather favour generalists or specialists, are small species overrepresented, are resources more extensively used than in temperate communities? One important property is fairly well established: Populations of most tropical species seem to be very small. Since a) in very many' cases distribution range is obviously very limited, since b) predator pressure is generally assumed to be higher in the tropics and c) recent - perhaps unduely generalized - results claim abundance fluctuations in the tropics fully comparable in their dimensions to those in the temperate zone, the question arises as to how these small populations can persist for seemingly long periods of time and avoid rapid extinction. Additionally treated PoInts concern detritivore communities, plant animal Interactions, key stone groups. Saving biodiversity in general and the tropical species and community richness in particular is one of the most urgent tasks of our generation, and biologists have to play a still more prominent role in this extremely important endeavor than they have in the past decades.},
  subject      = {Zoologie},
  language  = {de}
}
@article{KraemerNeubert1990,
  author    = {Kr{\"a}mer-Neubert, Sabine},
  title     = {Mundart und Geschichte des Miltenberger Raumes},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73135},
  year      = {1990},
  abstract  = {No abstract available},
  subject      = {Mundart},
  language  = {de}
}
@article{PressleyBorkowskiSchneider1990,
  author    = {Pressley, Michael and Borkowski, John G. and Schneider, Wolfgang},
  title     = {Good information processing: What it is and how education can promote it},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62127},
  year      = {1990},
  abstract  = {The nature of good information processing is outlined as determined by intact neurology, information stored in long-term memory, and general cognitive tendencies, attitudes, and styles. Educators can promote the development of good information processing by promoting what is in long-term memory. This can be accomplished by teaching important literary, scientific, and cultural knowledge; teaching strategies; motivating the acquisition and use of important conceptual knowledge and strategies; and encouraging the general tendencies supporting good information processing. Good information processing can be produced by years of appropriate educational input. Good information processors cannot be produced by short-term interventions.},
  subject      = {Psychologie},
  language  = {en}
}