@article{Heinsen1977, author = {Heinsen, Helmut}, title = {Quantitative anatomical studies on the postnatal development of the cerebellum of the albino rat}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-59881}, year = {1977}, abstract = {The quantitative postnatal changes of the cerebella of 65 Wistar rats aged 2-120 days have been examined. The cerebellar volume increases in two phases: The first phase lasts from birth to the seventh postnatal week. The second phase begins ten weeks post parturn and lasts for a Ionger period than the first phase. The cerebellar surface increases continuously from birth to the end of the seventh week. The volume of the external granular layer is maximal when the organ grows rapidly. The external granular layer has nearly disappeared 24 days after birth; the volume of the interaal granular layer is maximal at this time. Later on, the volume and the width of the interaal granular layer decrease. Myelinization of the cerebellar fibers and growth of the molecular layer run parallel to this decrease. The second late, but protracted growth of the cerebellum, ten weeks after birth, is due to an increase of the molecular and medullary layer. These findings are in good accord with histological, histochemical, and ultrastructural observations of other authors.}, subject = {Medizin}, language = {en} } @article{HeinsenHeinsen1983, author = {Heinsen, Helmut and Heinsen, Y. L.}, title = {Quantitative studies on regional differences in Purkinje cell dendritic spines and parallel fiber synaptic density}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-59917}, year = {1983}, abstract = {No abstact available}, subject = {Medizin}, language = {en} } @article{HeinsenHeinsen1983, author = {Heinsen, Helmut and Heinsen, Y. L.}, title = {Cerebellar capillaries: qualitative and quantitative observations in young and senile rats}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-59924}, year = {1983}, abstract = {Ultrastructural changes including reduced electron density, reduction in polysemes and cisternae of rough endoplasmic reticulum occur in the cytoplasrn of endothelial cells and pericytes in the cerebellar cortex of senile virgin female Han: WIST-rats in cornparison to 3-month old virgin rats. Processes of pericytes cover less of the capillary surface in the cerebellar cortex of senile rats; moreover, arithmetic and harmonic mean thickness of the endothelium and relative volume of mitochondria in endothelial cells and pericytes are reduced, w hereas the luminal diameter of the capillaries, harmonic and arithmetic mean thickness of pericytes and their processes and of the basal laminae between endothelial cells and astrocytes (abbreviated BAL 1), pericytes and astrocytes (BAL 2) and endothelial cells and pericytes (BAL 3) increase. The increase in harmonic mean thickness of the basal laminae is statistically significant (α<=0.05) and compensates for a decrease in thickness of capillary endothelium. Consequently, the total barrier mass and thickness of cerebellar cortical capillaries in senile animals is higher than in young individuals.}, subject = {Medizin}, language = {en} } @article{HeinsenHeinsen1983, author = {Heinsen, Helmut and Heinsen, Y. L.}, title = {Regionale Unterschiede der numerischen Purkinje-Zell-Dichte in Kleinhirnen von Albinoratten zweier St{\"a}mme}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45752}, year = {1983}, abstract = {The total number and the number of Purkinje cells per square millimeter of the surface of the cerebellar granular layer were measured in albino rats from two strains: Chbb-THOM-Wist and Han: SPRD. The total number of the Purkinje cells in the cerebellar vermian lobules L land L X with the exception of cells in the lobules VIb + c did not. differ significantly. Statistically significant differences were found between the individuals of the two rat strains and within single lobules of the cerebella concerning the cell density of Purkinje cells per square millimeter surface of the granular layer. The results suggest heterogeneity of the cerebellar cortex between cerebellar lobules and between albino rats derived from different strains.}, language = {de} } @article{HeinsenHeinsen1984, author = {Heinsen, Helmut and Heinsen, YL}, title = {Strain-specific differences in the vermian granular layer of albino rats}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45735}, year = {1984}, abstract = {Foliation of the cerebella of Sprague-Dawley rats (strain Han:SPRD) is more advanced than in Wistar rats (strain Chbb:THOM). The differences expressed as length of the granular layer in median sections were significant in lobules VIa, VIII, IX and X. The length of the other vermian lobules is generally higher in the former strain. With regard to the volume of the granular layer, the situation is reversed, indicating that the lateral extent and thickness of vermian lobules in Wistar rats (strain Chbb:THOM) is generally larger. These quantitative differences may express differences in cerebellar microcircuitry and fibre connections in the cortex of Wistar and Sprague-Dawley rats.}, language = {en} }