@article{ProdingerLazicHorasetal.2020, author = {Prodinger, Peter Michael and Lazic, Igor and Horas, Konstantin and Burgkart, Rainer and von Eisenhart-Rothe, R{\"u}diger and Weissenberger, Manuel and Rudert, Maximilian and Holzapfel, Boris Michael}, title = {Revision Arthroplasty Through the Direct Anterior Approach Using an Asymmetric Acetabular Component}, series = {Journal of Clinical Medicine}, volume = {9}, journal = {Journal of Clinical Medicine}, number = {9}, issn = {2077-0383}, doi = {10.3390/jcm9093031}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-213184}, year = {2020}, abstract = {Despite increasing numbers of primary hip arthroplasties performed through the direct anterior approach (DAA), there is a lack of literature on DAA revision arthroplasty. The present study was performed in order to evaluate outcomes and revision rates after revision through the DAA using an asymmetric acetabular component with optional intra- and extramedullary fixation. In a retrospective cohort study, we analyzed prospectively collected data of 57 patients (61 hips, 43 female, 18 male) who underwent aseptic acetabular component revision through the DAA with the abovementioned implant system between January 2015 and December 2017. The mean follow-up was 40 months (12-56). Survival rates were estimated using the Kaplan-Meier method. All complications were documented and functional outcomes were assessed pre- and postoperatively. Kaplan-Meier analysis revealed an estimated five-year implant survival of 97\% (confidence interval CI 87-99\%). The estimated five-year survival with revision for any cause was 93\% (CI 83-98\%). The overall revision rate was 6.6\% (n = 4). Two patients had to undergo revision due to periprosthetic infection (3.3\%). In one patient, the acetabular component was revised due to aseptic loosening four months postoperatively. Another patient suffered from postoperative iliopsoas impingement and was treated successfully by arthroscopic iliopsoas tenotomy. Two (3.3\%) of the revised hips dislocated postoperatively. The mean Harris Hip Score improved from 35 (2-66) preoperatively to 86 (38-100) postoperatively (p < 0.001). The hip joint's anatomical center of rotation was restored at a high degree of accuracy. Our findings demonstrate that acetabular revision arthroplasty through the DAA using an asymmetric acetabular component with optional intra- and extramedullary fixation is safe and practicable, resulting in good radiographic and clinical midterm results.}, language = {en} } @article{NellBurgkartGradletal.2011, author = {Nell, Manuel and Burgkart, Rainer H. and Gradl, Guntmar and von Eisenhart-Rothe, R{\"u}diger and Schaeffeler, Christoph and Trappe, Dennis and Prazeres da Costa, Clarissa and Gradinger, Reiner and Kirchhoff, Chlodwig}, title = {Primary extrahepatic alveolar echinococcosis of the lumbar spine and the psoas muscle}, series = {Annals of Clinical Microbiology and Antimicrobials}, volume = {10}, journal = {Annals of Clinical Microbiology and Antimicrobials}, number = {13}, doi = {10.1186/1476-0711-10-13}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-141796}, pages = {1-6}, year = {2011}, abstract = {Alveolar echinococcosis (AE) of human being caused by Echinococcus multilocularis is a rare but important zoonosis especially in tempered zones of middle Europe and Northern America with endemic character in many countries. Due to the long incubation period, various clinical manifestations, critical prognosis, and outcome AE presents a serious and severe disease. The primary focus of infection is usually the liver. Although secondary affection of visceral organs is possible extrahepatic AE is highly uncommon. Moreover, the involvement of bone and muscle presents with an even lower incidence. In the literature numerous cases on hepatic AE have been reported. However, extrahepatic AE involving bones and/or muscles was described very rarely. We report a case of an 80-year-old man with primary extrahepatic alveolar Echinococcosis of the lumbar spine and the psoas muscle. The etiology, diagnosis, differential diagnoses, treatment options and outcome of this rare disease are discussed in context with the current literature.}, language = {en} } @article{HolzapfelChhayaMelchelsetal.2013, author = {Holzapfel, Boris Michael and Chhaya, Mohit Prashant and Melchels, Ferry Petrus Wilhelmus and Holzapfel, Nina Pauline and Prodinger, Peter Michael and von Eisenhart-Rothe, R{\"u}diger and Griensven, Martijn van and Schantz, Jan-Thorsten and Rudert, Maximilian and Hutmacher, Dietmar Werner}, title = {Can Bone Tissue Engineering Contribute to Therapy Concepts after Resection of Musculoskeletal Sarcoma?}, series = {Sarcoma}, volume = {2013}, journal = {Sarcoma}, number = {Article ID 153640}, doi = {10.1155/2013/153640}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-132465}, pages = {10 p.}, year = {2013}, abstract = {Resection of musculoskeletal sarcoma can result in large bone defects where regeneration is needed in a quantity far beyond the normal potential of self-healing. In many cases, these defects exhibit a limited intrinsic regenerative potential due to an adjuvant therapeutic regimen, seroma, or infection. Therefore, reconstruction of these defects is still one of the most demanding procedures in orthopaedic surgery. The constraints of common treatment strategies have triggered a need for new therapeutic concepts to design and engineer unparalleled structural and functioning bone grafts. To satisfy the need for long-term repair and good clinical outcome, a paradigm shift is needed from methods to replace tissues with inert medical devices to more biological approaches that focus on the repair and reconstruction of tissue structure and function. It is within this context that the field of bone tissue engineering can offer solutions to be implemented into surgical therapy concepts after resection of bone and soft tissue sarcoma. In this paper we will discuss the implementation of tissue engineering concepts into the clinical field of orthopaedic oncology.}, language = {en} }