@article{UlrichsKuhlencordtMuellerRuchholtz1979,
  author    = {Ulrichs, Karin and Kuhlencordt, KM and M{\"u}ller-Ruchholtz, W.},
  title     = {Plating inhibition assay (PIA): a new test for cell mediated cytotoxicity},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45443},
  year      = {1979},
  abstract  = {No abstract available},
  language  = {en}
}
@article{DeltzMuellerHermelinkUlrichsetal.1981,
  author    = {Deltz, E. and M{\"u}ller-Hermelink, HK and Ulrichs, Karin and Thiede, A. and M{\"u}ller-Ruchholtz, W.},
  title     = {Development of graft-versus-host reaction in various target organs after small intestine transplantation},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45459},
  year      = {1981},
  abstract  = {The GVHRIL foHowing transplantation of small intestine are different from those found after bone marrow transplantation or spleen cell injections in that they show a remarka ble, significant prevalence of lesions within the intestinal mucosa. These findings are consistent with the observation that jntestinal lymphocytes newly formed in mesenteric lymph nodes predominantly home in on the intestine again.\& The degree of histologic alteration within different tissues indicates that the graft and the host may survive the lesions of the lymphatic tissues, whereas the severe intestinal lesions following GVHR may easily cause death of the recipient. With regard to clinical sman bowel transplantation two statements can be made: (l) GVHRIL play a significant role in small bowel trans~ plantation. (2) To minimize their biologic importance, a selective elimination of the graft's Jymph nodes by irradiation or surgical resection should be considered in view of the remarkable difference between GVHRIL in lymph nodes and in the graft's intestinal wall itself.},
  subject      = {Chirurgie},
  language  = {en}
}
@article{UlrichsDeltzThiedeetal.1982,
  author    = {Ulrichs, Karin and Deltz, E. and Thiede, A. and M{\"u}ller-Ruchholtz, W.},
  title     = {Lymphoid tissue transplantation in rats leads to a GVHR, inducing a specific T-cell mediated autoreactivity against MHC-antigens},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45420},
  year      = {1982},
  abstract  = {No abstract available},
  language  = {en}
}
@article{UlrichsSchangKelleretal.1984,
  author    = {Ulrichs, Karin and Schang, T. and Keller, R. and M{\"u}ller-Ruchholtz, W.},
  title     = {Reactivity of pancreas islet cells with antisera of known specificity},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45466},
  year      = {1984},
  abstract  = {No abstract available},
  language  = {en}
}
@article{UlrichsYuDunckeretal.1984,
  author    = {Ulrichs, Karin and Yu, MY and Duncker, D. and M{\"u}ller-Ruchholtz, W.},
  title     = {Immunosuppression by cytostatic drugs?},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45574},
  year      = {1984},
  abstract  = {In the present study, an attempt was made to characterize the immunomodulating abilities of the cytostatic drugs cydophosphamide, ifosfamide, vinblastine, vincristine, procarbazine, dacarbazine, 6-mercaptopurine, methotrexate, 5-f/uor-uracil and adriamycine in a defined experimental model. Varying combinations of drug plus transplantation alloantigen, (C3H-lymphocytes) were injected into Balb/c mice at different time intervals in vivo. The resulting T-effector cell reactivity was determined in vitro with the microcytotoxicity assay on day + 5 for primary (r) and day + 7 for secondary (2°) sensitized mice. According to the type of drug (alkylating agent vs. vinca alkaloid vs. antimetabolite vs. cytostatic antibiotic), the dosage (20\% LD50 vs. 60\% LD50), the state of sensitization (r vs. 2° sensitized recipients), and the time of drug application in relation to the antigen treatment on day 0 (in varying steps from day -6 to day +4), so-called "pharmaconantigen- variation-effects" (PA VE) were established for each of the investigated drugs in form of reaction profiles. The results were as folIows: (1) For almost alt substances, characteristic reaction profiles involving immunostimulation and/or immunosuppression could be established. Similarities in the profiles of different substances made it possible to classify the drugs according to different reaction types. The reaction type however is not definitely correlated to the biochemical mechanism of drug action. (2) The PA VE are decisively inf/uenced by so me of the biological parameters, such as the time of drug application in relation to the antigen treatment and the state of sensitization but relatively !ittle by the dosage of the drug. (3) Considering the different processes occurring du ring primary and secondary immune responses, the PAVE may give hints for a distinct manipulation of the immunoregulation and thus information on the immunobiological mechanism of drug action.},
  subject      = {Immunologie},
  language  = {en}
}
@article{UlrichsKellerMuellerRuchholtz1985,
  author    = {Ulrichs, Karin and Keller, R. and M{\"u}ller-Ruchholtz, W.},
  title     = {Serological demonstration and manipulation of passenger cells (PC) in pancreas islet grafts},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72944},
  year      = {1985},
  abstract  = {No abstract available},
  subject      = {Immunobiologie},
  language  = {en}
}
@article{UlrichsMuellerRuchholtz1985,
  author    = {Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.},
  title     = {Further Analyses of Pancreas Islet Immunogenicity, a Major Barrier to Successful Islet Transplantation},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45563},
  year      = {1985},
  abstract  = {No abstract available},
  subject      = {Chirurgie},
  language  = {en}
}
@article{UlrichsMuellerBuchholtz1985,
  author    = {Ulrichs, Karin and M{\"u}ller-Buchholtz, W.},
  title     = {MHC class II antigen expression on the various cells of normal and activated isolated pancreatic islets},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44722},
  year      = {1985},
  abstract  = {It is the aim of this study to characterize and quantify the cells within isolated rat islets that express MHC class 11 antigens. A set of five monoelonal antibodies and two polyclonal antisera of defined specificlty were used in combination with a newly devised procedure for three·dimensional immunofluorescence evaluation of intact islets. It is shown that in addition to passen· ger cells, such as Iymphocytes, macro· phages, and dendrlticlike cells, vascular endothelial and endocrine cells are also capable of expressing class 11 antigens. This expression Is strongly influenced by in vitro culture. pregnancy, streptozotocin- induced diabetes, transplantation trauma, and alloantigenic stimuli. The pos· sible role of the above cells in antigen presentation related to islet transplantation is discussed.},
  language  = {en}
}
@article{LausUlrichsMuellerRuchholtz1986,
  author    = {Laus, R. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.},
  title     = {Molecular Specificity of Human Heterophile Antibodies (HHA) in Normal Human Serum (NHS) Reacting with Xenogeneic Cells.},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72921},
  year      = {1986},
  abstract  = {No abstract available},
  subject      = {Immunobiologie},
  language  = {en}
}
@article{KekowUlrichs1986,
  author    = {Kekow, J. and Ulrichs, Karin},
  title     = {Determination of total immunoreactive rat insulin (IRI) in culture supernatants of rat islets by an enzyme linked immunosorbent assay (ELISA) as a routine method to assess the viability of rat islets prior to their use in islet transplantation},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72989},
  year      = {1986},
  abstract  = {No abstract available},
  subject      = {Immunobiologie},
  language  = {en}
}
@article{DeltzUlrichsSchacketal.1986,
  author    = {Deltz, Eberhard and Ulrichs, Karin and Schack, Thorsten and Friedrichs, Birgit and M{\"u}ller-Ruchholtz, Wolfgang and M{\"u}ller-Hermelink, Hans K. and Thiede, Arnulf},
  title     = {Graft-versus-host reaction in small bowel transplantation and possibilities for its circumvention},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-64425},
  year      = {1986},
  abstract  = {No abstract available},
  subject      = {D{\"u}nndarm},
  language  = {en}
}
@article{UlrichsNoethlingKelleretal.1987,
  author    = {Ulrichs, Karin and N{\"o}thling, R. and Keller, R. and Heusermann, U. and M{\"u}ller-Buchholtz, W.},
  title     = {Genetically determined variation of constitutive major histocompatibility complex class II antigen expression in various rat strains and cell types},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44769},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Chirurgie},
  language  = {en}
}
@article{MuellerBuchholtzLeyhausenPetersonetal.1987,
  author    = {M{\"u}ller-Buchholtz, W. and Leyhausen, G. and Peterson, P. and Schubert, G. and Ulrichs, Karin},
  title     = {A simple methodological principle for large scale extraction and purification of collagenase-digested islets},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44770},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Chirurgie},
  language  = {en}
}
@article{KekowUlrichsMuellerRuchholtzetal.1987,
  author    = {Kekow, J. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W. and Gross, WL},
  title     = {Pancreas transplantation: a study of insulin secretion in isolated islets of Langerhans and in sera using a new enzyme-linked immunosorbent assay},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45229},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Chirurgie},
  language  = {en}
}
@article{FalkUlrichsMuellerRuchholtz1987,
  author    = {Falk, W. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.},
  title     = {15-Deoxyspergualin (a new guanidine-like drug) blocks T lymphocyte proliferation},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45215},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Chirurgie},
  language  = {en}
}
@article{DickneiteSchorlemmerSedlaceketal.1987,
  author    = {Dickneite, G. and Schorlemmer, H. U. and Sedlacek, H. H. and Falk, W. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.},
  title     = {Suppression of macrophage function and prolongation of graft survival by the new guanidinic-like structure, 15-deoxyspergualin},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86991},
  year      = {1987},
  abstract  = {No abstract available.},
  subject      = {Makrophage},
  language  = {en}
}
@article{KekowUlrichsMuellerRuchholtzetal.1988,
  author    = {Kekow, J{\"o}rn and Ulrichs, Karin and M{\"u}ller-Ruchholtz, Wolfgang and Gross, Wolfgang L.},
  title     = {Measurement of rat insulin. Enzyme-linked immunosorbent assay with increased sensitivity, high accuracy, and greater practicability than established radioimmunoassay},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45543},
  year      = {1988},
  abstract  = {Total immunoreactive insulin (IRI) is conventionally determined by radioimmunoassays. IR! measurement in rats can be made more sensitive, accurate, and practical, as demonstrated by a new modified enzyme-linked immunosorbent assay (ELlSA). It is characterized by indirect binding of an anti-insulin antibody by an antiglobulin antibody and uses the principle of competitive saturation. In this ELlSA, IRI can be determined in a wide range of concentrations, corresponding to the standards. The standard curve ranges from 100 to 0.049 ng/mllRI (1 ng/ml - 23.4 JLU/ml - 172 pM rat insulin). The statistical analysis shows between- and within-assay coefficients of variation of :515\%. Diabetes 37:321-26,1988},
  subject      = {Chirurgie},
  language  = {en}
}
@article{UlrichsMuellerRuchholtz1988,
  author    = {Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.},
  title     = {Expression of MHC Structures on Immunologically Reactive and Non Reactive Cells in Islets of Langerhans and Other Tissues},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45557},
  year      = {1988},
  abstract  = {No abstract available},
  subject      = {Chirurgie},
  language  = {en}
}
@article{WinotoMorbachLeyhausenMuellerRuchholtzetal.1988,
  author    = {Winoto-Morbach, S. and Leyhausen, G. and M{\"u}ller-Ruchholtz, W. and Ulrichs, Karin},
  title     = {The Electromagnetic Separation Principle: A Basis for Human Pancreatic Islet Transplantation},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-82520},
  year      = {1988},
  abstract  = {No abstract available},
  subject      = {Allergie},
  language  = {en}
}
@article{VonGaudeckerUlrichsMuellerRuchholtz1989,
  author    = {Von Gaudecker, Brita and Ulrichs, Karin and M{\"u}ller-Ruchholtz, Wolfgang},
  title     = {Immunoelectron microscopic localization of MHC structures in isolated pancreatic rat islets},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45596},
  year      = {1989},
  abstract  = {An immunogold-silver enhancement technique, which combines effective labeling of viable isolated islets with the ultrastructural resolution of cytological details, was applied in electron microscopy to identify major histocompatibility complex (MHC) structures on islet cells. Incubation of freshly isolated islets from CAP (RT1C) and LEW (RT1') rats with OX18, an MHC class I antibody, showed strong positive reactivity in macrophages and/or dendritic-like cells (M0-DCs) and vascular endothelial cells (VEs) and a comparatively weaker reactivity in endocrine a-, p-, and 8-ce"s. With MHC class" antibody OX6 (anti-I-A), M0-DCs were strongly labeled in both rat strains on the surface and on internal structures. Three of five particularly high titered batches of OX6 revealed MHC class" expression on VE and p-ce"s. Four days of in vitro culture in combination with a high concentration of glucose and interferon-'Y induced strong enhancement of MHC class I structures and, to a lesser extent, class " structures on p-ce"s.},
  subject      = {Immunbiologie},
  language  = {en}
}