@article{HuangHuKrummenacheretal.2022,
  author    = {Huang, Mingming and Hu, Jiefeng and Krummenacher, Ivo and Friedrich, Alexandra and Braunschweig, Holger and Westcott, Stephen A. and Radius, Udo and Marder, Todd B.},
  title     = {Base-Mediated Radical Borylation of Alkyl Sulfones},
  series = {Chemistry—A European Journal},
  volume    = {28},
  journal   = {Chemistry—A European Journal},
  number    = {3},
  doi       = {10.1002/chem.202103866},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-257281},
  pages     = {e202103866},
  year      = {2022},
  abstract  = {A practical and direct method was developed for the production of versatile alkyl boronate esters via transition metal-free borylation of primary and secondary alkyl sulfones. The key to the success of the strategy is the use of bis(neopentyl glycolato) diboron (B\(_{2}\)neop\(_{2}\)), with a stoichiometric amount of base as a promoter. The practicality and industrial potential of this protocol are highlighted by its wide functional group tolerance, the late-stage modification of complex compounds, no need for further transesterification, and operational simplicity. Radical clock, radical trap experiments, and EPR studies were conducted which show that the borylation process involves radical intermediates.},
  language  = {en}
}