@article{GraserLiedtkeJakob2021,
  author    = {Graser, Stephanie and Liedtke, Daniel and Jakob, Franz},
  title     = {TNAP as a new player in chronic inflammatory conditions and metabolism},
  series = {International Journal of Molecular Sciences},
  volume    = {22},
  journal   = {International Journal of Molecular Sciences},
  number    = {2},
  issn      = {1422-0067},
  doi       = {10.3390/ijms22020919},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-258888},
  year      = {2021},
  abstract  = {This review summarizes important information on the ectoenzyme tissue-nonspecific alkaline phosphatase (TNAP) and gives a brief insight into the symptoms, diagnostics, and treatment of the rare disease Hypophosphatasia (HPP), which is resulting from mutations in the TNAP encoding ALPL gene. We emphasize the role of TNAP beyond its well-known contribution to mineralization processes. Therefore, above all, the impact of the enzyme on central molecular processes in the nervous system and on inflammation is presented here.},
  language  = {en}
}
@article{HoehnFrimmelDebailleetal.2021,
  author    = {H{\"o}hn, Stefan and Frimmel, Hartwig E. and Debaille, Vinciane and Price, Westley},
  title     = {Pre-Klondikean oxidation prepared the ground for Broken Hill-type mineralization in South Africa},
  series = {Terra Nova},
  volume    = {33},
  journal   = {Terra Nova},
  number    = {2},
  doi       = {10.1111/ter.12502},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-218545},
  pages     = {168 -- 173},
  year      = {2021},
  abstract  = {New Cu isotope data obtained on chalcopyrite from the Black Mountain and the Broken Hill deposits in the medium- to high-grade metamorphic Aggeneys-Gamsberg ore district (South Africa) require a revision of our understanding of the genesis of metamorphic Broken Hill-type massive sulphide deposits. Chalcopyrite from both deposits revealed unusually wide ranges in δ\(^{65}\)Cu (-2.41 to 2.84 per mille NIST 976 standard) in combination with distinctly positive mean values (0.27 and 0.94 per mille, respectively). This is interpreted to reflect derivation from various silicate and oxide precursor minerals in which Cu occurred in higher oxidation states. Together with the observation of a typical supergene base metal distribution within the deposits and their spatial association with an unconformity only meters above the ore horizon, our new data are best explained by supergene oxidation of originally possibly SEDEX deposits prior to metamorphic sulphide formation, between the Okiepian (1,210-1,180 Ma) and Klondikean (1,040-1,020 Ma) orogenic events.},
  language  = {en}
}