@article{SchneiderSchauliesLiebertBaczkoetal.1989,
  author    = {Schneider-Schaulies, Sibylle and Liebert, U. G. and Baczko, K. and Cattaneo, R. and Billeter, M. and ter Meulen, V.},
  title     = {Restriction of measles virus gene expression in acute and subacute encephalitis in Lewis rats},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62266},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Virologie},
  language  = {en}
}
@article{RaulfRobertsonSchartl1989,
  author    = {Raulf, F. and Robertson, S. M. and Schartl, Manfred},
  title     = {Evolution of the neuron-specific alternative splicing product of the c-src proto-oncogene},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61796},
  year      = {1989},
  abstract  = {The observation of a slower migrating form of pp6oc-src in neural tissue of chicken and mouse has recently been shown to be due to an alternative transcript form of tbe c-src gene (Martinez et al.: Science 237:411-415, 1987; Levy et al.: Mol Cell Bio17:4142- 4145, 1987). An insertion of 18 basepairs between exons 3 and 4, presumed to be due to alternative splicing of a mini-exon, gives rise to six amino acid residues not found in the non-neuronal (termed flbroblastic) form of pp60\(^{c-src}\). Wehave addressed the question of the evolutionary origin of the c-src neuronal insert · and its functional signiflcance regarding neural-speciflc expression of the c-src gene. To this end we have investigated whether the c-src gene of a lower verlebrate (the teleost fish Xiphophorus) gives rise to a neural-specific transcript in an analogous manner. We could show that the fish c-src gene does encode for a "fibroblastic" and a "neuronal" form of transcript and that the neuronal transcript does indeed arise by way of alternative splicing of a mini-exon. The miniexon is also 18 basepairs long and we could demoostrate directly that this exon lies within the intron separating exons 3 and 4. For comparative purposes we have examined whether the fish c-yes gene, the member of the src gene family most closely related to c-src, also encodes a neural tissue-specific transcript. No evidence for a second transcript form in brain was obtained. This result suggests that the mini-exon arose within the c-src gene lineage sometime between the srclyes gene duplication event and the divergence of the evolutionary lineage giving rise to the teleost fish. Published genomic sequence of src-related genes in Drosophila and our own results with Hydra demoostrate no intron in these species at the analogous location, consistent with first appearance of this mini-exon sometime between 550 and 400 million years ago.},
  subject      = {Physiologische Chemie},
  language  = {en}
}
@article{WittbrodtAdamMalitscheketal.1989,
  author    = {Wittbrodt, J. and Adam, D. and Malitschek, B. and Maueler, W. and Raulf, F. and Telling, A. and Robertson, M. and Schartl, Manfred},
  title     = {Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61800},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Physiologische Chemie},
  language  = {en}
}
@article{BernardsSchacklefordGerberetal.1989,
  author    = {Bernards, R. and Schackleford, G. M. and Gerber, M. R. and Horowitz, J. M. and Friend, S. H. and Schartl, Manfred and Bogenmann, E. and Rapaport, J. M. and Mcgee, T. and Dryja, T. P.},
  title     = {Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61819},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Physiologische Chemie},
  language  = {en}
}
@article{EngelsPeyerimhoff1989,
  author    = {Engels, Bernd and Peyerimhoff, S.D.},
  title     = {Theoretical study of FC\(_2\)H\(_4\)},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58824},
  year      = {1989},
  abstract  = {Large-scale multireference configuration interaction (MRD-CI) calculations in a quite flexible AO basis are employed to study the energy hypersurface for the reaction intermediate FC\(_2\)H\(_4\) • The reaction F + C\(_2\)H\(_4\) -> FC\(_2\)H\(_4\) as weil as the 1,2 migration of the fluorine atom in FC\(_2\)H\(_4\) is investigated. In addition the rotation around the CC bond in the optimum conformation is studied. The absolute minimum in the potential energy is found for the asymmetric structure but the symmetric structure is also found to be stable with respect to the dissociation, so that a shuttling of the fluorine atom is in principle possible but highly unlikely because ( l) the activation energy is high ( II 5-130 kJ fmol) and the saddle point lies only 4(}-50 kJ jmol below the dissociation Iimit of F + C\(_2\)H\(_4\) and (2) the competitive motion, i.e., rotation around the CC axis, is nearly free (I 1-17 kJ/mol).},
  subject      = {Organische Chemie},
  language  = {en}
}
@article{EngelsPeyerimhoff1989,
  author    = {Engels, Bernd and Peyerimhoff, S.D.},
  title     = {The hyperfine coupling constants of the X\(^3\)Σ\(^-\) state of NH : Influence of polarization functions and configuration space on the description of spin polarization},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58832},
  year      = {1989},
  abstract  = {The hyperfine coupling constants for the \(^3\)Σ\(-\) ground state of the NH molecule are determined by configuration interaction calculations whereby the infl.uence of polarization functions as weil as of the configuration space on the spin polarization mechanism is analysed. The dipolar part Au(N) and Au(H) can be obtained very reliably without much computational effort (A .. (N) == -45·3 MHz and A"(H) = -62·3 MHz). The value for the isotropic contribution a1.., in the best AO basis and MRD-CI treatment is - 64·5 MHz for H and 16·6 MHz for nitrogen compared to the corresponding experimental quantities of -66 MHz and 19 MHz respectively. Their determination depends on a subtle balance of the lu, 2u and 3u shell correlation description, whereby the dominant contribution to a1..,(H) results from the 2u shell. It is shown that the often good agreement of a110 values with experiment in a small basis singledouble configuration interaction treatment results from a cancellation of two errors.},
  subject      = {Organische Chemie},
  language  = {en}
}
@article{EngelsPeyerimhoff1989,
  author    = {Engels, Bernd and Peyerimhoff, S.D.},
  title     = {Study of orbital transformations in configurational interaction calculation of hyperfine coupling in nitrogen and CH molecule},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58847},
  year      = {1989},
  abstract  = {Multi-reference configuration interaction calculations employing various orbital transformations are undertaken to obtain the isotropic hyperfine coupling constant a\(_{iso\) in nitrogen and a\(_{iso\) (H) in the CH molecule. The natural orbital (NO) basis is found to be more effective than the simple RHF-MO basis; the most obvious is a basis of spin natural orbitals (SNO). It is found that a\(_{iso\) is approached from opposite sides in the NO and 2s shell SNO basis if the CI expansion is increased. Both results are within a few percent of the full CI Iimit for the nitrogen atorn (in the given AO basis) and the experimental value for Hin the CH radical. Various features ofthe SNO are discussed.},
  subject      = {Organische Chemie},
  language  = {en}
}
@article{KarnaGreinEngelsetal.1989,
  author    = {Karna, S. and Grein, F. and Engels, Bernd and Peyerimhoff, S.D.},
  title     = {The hyperfine coupling constants of \(^{19}\)F\(_2\)},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58817},
  year      = {1989},
  abstract  = {The isotropic (a\(_{iso}\)) and dipolar (A\(_{dip}\)) hyperfine coupling constants of 19F2 were obtained from MRD-CI wave functions using a variety of basis sets. In series I, increasing numbers of d functions were added to a 5s4p contracted Huzinaga!Dunning basis. In series II, the 5s3p basis set was uncontracted in several steps until 9s5p was reached, to which were added from one to three d-polarization functions. Cl parameters (selectioo threshoids and the number of reference coofiguratioos) were also varied. A study of the R dependence of aiso and Adip was perfonned. The best values obtained at R\(_e\) are 260 G for a\(_{iso}\) and 308 G for A\(_{dip}\)• compared with experimental values of about 280 G for a;10 and 320 G for A\(_{dip}\)·},
  subject      = {Organische Chemie},
  language  = {en}
}
@article{WieberBurschkaBauer1989,
  author    = {Wieber, Markus and Burschka, Christian and Bauer, Bernd},
  title     = {Kristallstruktur von Bis(diethyldithiocarbamato)phenylphosphan und Synthese einiger Mono- und Bis(dioganyldithiocarbamato)phosphane},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-57814},
  year      = {1989},
  abstract  = {Durch Umsetzung der jeweiligen Chiaraphosphane mit den entsprechenden Natriumdithiocarbamaten k{\"o}nnen folgende Verbindungen erhalten werden: Verbindungen des Typs RP(S\(_2\)CNR\(_2\)')\(_2\) mit R = CH\(_3\), C\(_6\)H\(_5\); R' = CH\(_3\) , C\(_2\)H\(_5\), CH(CH\(_3\))\(_2\). C\(_6\)H\(_5\) ; Verbindungen des Typs (C\(_6\)H\(_5\)) \(_2\)PS\(_2\)CNR\(_2\) mit R' = CH\(_3\) , CH(CH\(_3\))\(_2\) sowie [(C\(_6\)H\(_5\)))\(_2\)PS\(_2\)CN(CH\(_3\))CH\(_2\)--]\(_2\). Die Kristallstruktur von C\(_6\)H\(_5\)P(S\(_2\)CN(C\(_2\)H\(_5\))\(_2\))\(_2\) zeigt, daß sich der Trend zu schw{\"a}cher ausgepr{\"a}gter zweiz{\"a}hniger Bindungsweise der Dithiocarbamatliganden in der homologen Reihe RE(S\(_2\)CN(C\(_2\)H\(_5\))\(_2\))\(_2\); E = Bi, Sb, As, P f{\"u}r E = P fortsetzt.},
  subject      = {Anorganische Chemie},
  language  = {de}
}
@article{Ellgring1989,
  author    = {Ellgring, Johann Heinrich},
  title     = {Facial expression as a behavioral indicator of emotional states},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58753},
  year      = {1989},
  abstract  = {This article gives an overview of possibilities for the assessment offacial behavior. With regard to validity, results from a longitudinal study of 36 depressed patients and nine controls as weil as often schizophrenic patients and their relatives will be referred to. These results are used to illustrate the following principles which have to be taken into account when studying facial behavior: a) communication strongly facilitates facial expression, b) activation of facial behavior follows the "principle of least effort", and c) the principle of individual specificity applies to the association of nonverbal behavior and mood states. Making allowance for these principles has, among others, consequences a) for situations or conditions under which to asses behavior (specifically conditions of communication), b) for data analysis (e.g., dealing with frequent and rare events), and c) for empirical or experimental strategies (e.g., aggregation of single-case longitudinal comparisons). From the results on facial behavior during depression it can be concluded that the nonverbal reaction tendencies of endogenous and neurotic depressed patients differ. Moreover, the differential behavioral pattems observed cast doubt on the assumption of a homogeneity of affects in depression. Taking into account the conditions which govern it, facial behavior has proved to be a valid and, especially, a differential indicator for pathoIogic affective states and their changes. Given the fact that a psychiatric illness generally incorporates emotional problems it is more than surprising that little attention has been paid to the systematic study of emotional behavior. Some of the reasons for this will be clarified in the following.},
  subject      = {Psychologie},
  language  = {en}
}
@inproceedings{BossertMeilerLaessleetal.1989,
  author    = {Bossert, Sabine and Meiler, Caroline and Laessle, Reinhold and Ellgring, Heiner and Pirke, Karl-Martin},
  title     = {Responses to visual perception of food in eating disorders},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58762},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Psychologie},
  language  = {en}
}
@article{CarrKurtzSchneideretal.1989,
  author    = {Carr, Martha and Kurtz, Beth E. and Schneider, Wolfgang and Turner, Lisa A. and Borkowski, John G.},
  title     = {Strategy acquisition and transfer among American and German children: Environmental influences on metacognitive development},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62082},
  year      = {1989},
  abstract  = {This study explored the differential effects of strategy training on German and American elementaryschool children and assessed the role of parents in the development of their children's strategic behavior and metacognition. 184 German and 161 American children were pretested on memory and metamemory tasks. Children were then assigned to either an organizational strategy training condition or a control condition. All children were tested on the maintenance and far-transfer of the strategy and task-related metamemory 1 week following training. Parents completed questionnaires about strategy instruction in the home. Strategy maintenance and metacognition were reassessed 6 months following training. German children were more strategic than American children. Instructed children performed better than control children. German parents reported more instruction of strategies in the home. These data suggest that formal education is responsible for aspects of cognitive development that have sometimes been viewed as a function of age.},
  subject      = {Psychologie},
  language  = {en}
}
@article{HackerGadebergOrskov1989,
  author    = {Hacker, J{\"o}rg and Gadeberg, Ole V. and Orskov, Ida},
  title     = {Role of alpha-Hemolysin for the in vitro Phagocytosis and intracellular killing of Escherichia coli},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73019},
  year      = {1989},
  abstract  = {The_role of a-hemolysin for the elimination of Eschericbia coli by phagocyres in vitro was investigated using sets of isogenic strains which included wild-type a -hemolyric srrains, derived strains with a reduced production of a-hemolysin and derived nonhemolytic strains. Phagocyrosis and intracellular killing of the bacteria by human blood granulocytes or monocytes were measured using growth inhibition rechniques. a-hemolytic strains were phagocytosed and killed ro a Jesser extent than isogenic strains with a reduced production of o:hemoJysin and isogenic nonhemolytic strains. The results obrained with granulocyres were similar to rhose obtained with monocyres although the elimination of bacteria by monocytes was less than that by granulocytes. These resulcs strongJy suggest that production of ahemolysin is a means by which E. coli counteracrs the activity of phagocytes by injuring these cells with the toxin.},
  subject      = {Escherichia coli},
  language  = {en}
}
@article{SirenFeuerstein1989,
  author    = {Sir{\´e}n, Anna-Leena and Feuerstein, G.},
  title     = {Effect of PAF and BN 52021 on cardiac function and regional blood flow in the conscious rat},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63145},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Neurobiologie},
  language  = {en}
}
@article{SirenFeuerstein1989,
  author    = {Sir{\´e}n, Anna-Leena and Feuerstein, G.},
  title     = {Thyrotropin releasing hormone-induced hindquarter vasodilation is mediated by \(\beta _2\)-adrenoceptors},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63155},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Neurobiologie},
  language  = {en}
}
@article{SirenFeuerstein1989,
  author    = {Sir{\´e}n, Anna-Leena and Feuerstein, G.},
  title     = {Hemodynamic effects of endothelin after systemic and central nervous System administration in the conscious rat},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63165},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Neurobiologie},
  language  = {en}
}
@article{WeigelMeyerSebald1989,
  author    = {Weigel, U. and Meyer, M. and Sebald, Walter},
  title     = {Mutant proteins of human interleukin 2. Renaturation yield, proliferative activity and receptor binding},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62543},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Biochemie},
  language  = {en}
}
@article{FlueggeFischerGrossetal.1989,
  author    = {Fl{\"u}gge, U. I. and Fischer, K. and Gross, A. and Sebald, Walter and Lottspeich, F. and Eckerskorn, C.},
  title     = {The triose phosphate-3-phosphoglycerate-phosphate translocator from spinach chloroplasts: nucleotide sequence of a full-length cDNA clone and import of the in vitro synthesized precursor protein into chloroplasts},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62559},
  year      = {1989},
  abstract  = {No abstract available},
  subject      = {Biochemie},
  language  = {en}
}
@article{SirenPaakkariGoldsteinetal.1989,
  author    = {Sir{\´e}n, Anna-Leena and Paakkari, P. and Goldstein, D. S. and Feuerstein, G.},
  title     = {Mechanism of central hemodynamic and sympathetic regulation by µ-opioid receptors: Effects of dermorphin in the conscious rat},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63123},
  year      = {1989},
  abstract  = {The effects of i.c.v. administered dermorphin, a highly selective \(\mu\)-opioid agonist, on cardiac function and renal, mesenteric and hindquarter blood ftow were studied in conscious rats. Core temperature, blood gases, arterial plasma levels of norepinephrine, epinephrine, dopamine, 3,4-dihydroxyphenylalanine and dihydroxyphenylacetic acid (DOPAC) also were examined. Cardiac output was rneasured using a thermodilution technique and regional blood ftows using directional pulsed Doppler velocimetry. Dermorphin, at doses of 0.1-100 nmol/kg, increased blood pressure and hindquarter blood flow, renal and mesenteric resistance, and core temperature. Higher doses (1-5 \(\mu\)mol/kg) caused respiratory depression, acidosis, and shock despite profaund sympatho-adrenomedullary stimulation. Circulating Ieveis of catecholamines were significantly increased at the dermorphin doses of 0.1-1 00 nmol/kg. At the 100 nmol/kg dose, plasma levels of epinephrine, norepinephrine, the dopamine metabellte dihydroxyphenylacetic acid and the catecholamine precursor 3,4,-dihydroxyphenylalanine were increased by 2-15-fold. The data indicate that mu opioid receptor Stimulation exerts potent effects on cardiorespiratory functions, activates the sympathoadrenomedullary system and produces a pattem of blood flow changes consistent with the stress-induced •detense· response (skeletal muscle vasodilation and splanchnic vasoconstriction). Excessive mu opioid receptor Stimulation Ieads to shock due to respiratory and hemodynamic collapse.},
  subject      = {Neurobiologie},
  language  = {en}
}
@article{SirenEimerlFeuerstein1989,
  author    = {Sir{\´e}n, Anna-Leena and Eimerl, J. and Feuerstein, G.},
  title     = {L-649,923 : An antagonist of cardiac and vascular leukotriene D\(_4\) receptors},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63134},
  year      = {1989},
  abstract  = {The capacity of L-649,923-sodium ( ßS, -yR * )-4-(3-( 4-acetyl-3-hydroxy-2-propylphenoxy)propylthio)-- y-hydroxy-ß-methylbenzene butanoate-to block vascular receptors of leukotriene D\(_4\) ( L TD\(_4\)) was examined in the conscious rat. Hindquarter (HQ), renal, and mesenteric blood flow and vascular resistance were evaluated in the conscious rat chronically equipped with miniaturized Doppler probes for organ blood flow measurement by directional pulsed Doppler technique. In addition, cardiac outpul was measured by thermodilution technique in conscious rats equipped with minithermistors in the ascending aorta. Systemic hemodynamic variables. mean arterial pressure, and heart rate were monitored through femoral catheters. L TD\(_4\) (I or 10 \(\mu\)g/kg) produced a marked dose dependent increase in the mesenteric vascular resistance associated with a marked decrease in blood flow whereas no consistent effects were demonstrated in the renal circulation. L TD\(_4\) • at I \(\mu\)g/kg. increased the HQ blood flow whereas the higher dose of LTD\(_4\) produced a biphasic response: an early increase followed by a decrease in blood flow. Infusion of L TD\(_4\) • 3 \(\mu\)g/kg per min over 10 min decreased cardiac output and increased total peripheral resistance. L-649,923 (10 or 30 mg/kg, i.v.) effectively blocked the L TD4-induced mesenteric constriction and the second I phase of HQ vasoconstriction but did not modify the , LTD\(_4\) induced HQ vasodilation. L-649,923 also effectively attenuated the cardiac effects of LTD\(_4\) infusion. I These studies suggest that L-649,923 could preserve cardiac and vascular functions in pathologic states mediated by cysteinylleukotrienes, such as traumatic or endotoxin shock. Key Words: Leukotriene D4 -Cardiovascular system- Leukotriene antagonist- Mesenteric blood tlow-Renal blood flow-Hindquarter blood flowAnaphylaxis.},
  subject      = {Neurobiologie},
  language  = {en}
}