@article{LeeEyerFelgenhaueretal.2015,
  author    = {Lee, Marcel and Eyer, Florian and Felgenhauer, Norbert and Klinker, Hartwig H. F. and Spinner, Christoph D.},
  title     = {Overdose of dolutegravir in combination with tenofovir disaproxil fumarate/emtricitabine in suicide attempt in a 21-year old patient},
  series = {AIDS Research and Therapy},
  volume    = {12},
  journal   = {AIDS Research and Therapy},
  number    = {18},
  doi       = {10.1186/s12981-015-0054-y},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-151994},
  year      = {2015},
  abstract  = {A 21 year old MSM patient with newly diagnosed HIV infection was hospitalized in our department after ingestion of an overdose of his antiretroviral therapy (ART) comprising dolutegravir (DTG - Tivicay\(^{®}\)) and tenofovir disaproxil fumarate/emtricitabine (Truvada\(^{®}\)) in suicidal intention. On admission, the patient did not show any clinical signs of intoxication and laboratory findings were unremarkable. After 6 hours of intensive care monitoring, the patient was referred to a psychiatric clinic. 5 days after the day of intoxication, serum creatinine levels increased to high normal values (1.2 mg/dl). However, levels never exceeded the upper threshold. 8 and 12 weeks later, serum creatinine normalized to levels measured prior to the intoxication. No other adverse events occurred, and the patient does not suffer from permanent impairments.},
  language  = {en}
}