@article{OckermannHeadleyLizioetal.2021, author = {Ockermann, Philipp and Headley, Laura and Lizio, Rosario and Hansmann, Jan}, title = {A Review of the Properties of Anthocyanins and Their Influence on Factors Affecting Cardiometabolic and Cognitive Health}, series = {Nutrients}, volume = {13}, journal = {Nutrients}, number = {8}, issn = {2072-6643}, doi = {10.3390/nu13082831}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-245116}, year = {2021}, abstract = {The incidence of cardiovascular and metabolic diseases has increased over the last decades and is an important cause of death worldwide. An upcoming ingredient on the nutraceutical market are anthocyanins, a flavonoid subgroup, abundant mostly in berries and fruits. Epidemiological studies have suggested an association between anthocyanin intake and improved cardiovascular risk, type 2 diabetes and myocardial infarct. Clinical studies using anthocyanins have shown a significant decrease in inflammation markers and oxidative stress, a beneficial effect on vascular function and hyperlipidemia by decreasing low-density lipoprotein and increasing high-density lipoprotein. They have also shown a potential effect on glucose homeostasis and cognitive decline. This review summarizes the effects of anthocyanins in in-vitro, animal and human studies to give an overview of their application in medical prevention or as a dietary supplement.}, language = {en} }