@incollection{HandmanMitchellMcConvilleetal.1987,
  author    = {Handman, E. and Mitchell, G. F. and McConville, M. J. and Moll, Heidrun},
  title     = {Towards a carbohydrate-based vaccine against leishmaniasis},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33827},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  year      = {1987},
  abstract  = {No abstract available},
  language  = {en}
}
@article{SchneiderBrun1987,
  author    = {Schneider, Wolfgang and Brun, Hedwig},
  title     = {The role of context in young children's memory performance: Istomina revisited},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-52726},
  year      = {1987},
  abstract  = {According to more recent studies on memory development in young children, preschoolers and kindergarteners are able to demonstrate surprisingly good memory skills in natural as weH as in laboratory-type settings. This finding is not consistent with the results of a study by Istomina (1975), conducted in 1948, leading to the concJusion that (a) preschoolers do not use voluntary remembering, and (b) children generally recall better in play situations than in typical experimental settings. In this study, two experiments were conducted to replicate Istomina's research. In the first, it was shown that Istomina's findings were replicable when methodological problems in the procedure were ignored. Experiment 2 improved methodologically upon Istomina's experimental methods and did not produce results to support her concJusions. Four- and 6-year-olds showed voluntary memory in play activities as weH as in laboratory-type settings, and remembered equally weB in both contexts. The results did not support the assumption that memory performance in young children can be substantially facilitated by motivating contexts.},
  subject      = {Psychologie},
  language  = {en}
}
@article{RoemischTropschugSebaldetal.1987,
  author    = {R{\"o}misch, J. and Tropschug, M. and Sebald, Walter and Weiss, H.},
  title     = {The primary structure of cytochrome c\(_1\) from Neurospora crassa},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62578},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Biochemie},
  language  = {en}
}
@article{FeuersteinSiren1987,
  author    = {Feuerstein, Giora and Sir{\´e}n, Anna-Leena},
  title     = {The Opioid System in cardiac and vascular regulation of normal and hypertensive states},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-47418},
  year      = {1987},
  abstract  = {The endogenous opioid system includes three major families of peptides: dynorphins (derived from pre-proenkephalin B), endorphins (derived from pre-proopiomelanocortin), and enkephalins (derived from pre-proenkephalin A). Multiple species of opioid peptides are derived from these major precursors and many of them possess potent cardiovascular properties. Opioid peptides and opioid receptors, of which multiple forms have been defined, are present in the central nervous system and peripheral neural elements. In the central nervous system, opioid peptides and receptors are found in forebrain and hindbrain nuclei involved in baroregulation, sympathoadrenal activation, and several other vital autonomic functions. In the periphery, opioid peptides are found in autonomic ganglia, adrenal gland, heart, and other organs; multiple opioid receptors are also found in vascular tissue, heart, and kidneys. Although little is known to date on the regulatory mechanisms of the opioid system in normal cardiovascular states, it became clear that cardiovascular stress situations substantially modify the activity of the endogenous opioid system. The purpose of this review is to clarify the sites of interaction of the opioid system with all major components of the cardiovascular system and indicate the potential role of this system in the ontogenesis of cardiac malfunction, vascular diseases, and hypertension.},
  subject      = {Medizin},
  language  = {en}
}
@article{SchneiderKoerkelWeinert1987,
  author    = {Schneider, Wolfgang and K{\"o}rkel, Joachim and Weinert, Franz E.},
  title     = {The effects of intelligence, self-concept, and attributional style on metamemory and memory behaviour},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62050},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Psychologie},
  language  = {en}
}
@article{WilhelmZaccagnini1987,
  author    = {Wilhelm, Gernot and Zaccagnini, C.},
  title     = {T. Karrāna 3, T. Ḫirbat Ṣālih: 2nd Campaign},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-82943},
  year      = {1987},
  abstract  = {no Abstract available},
  subject      = {Alter Orient},
  language  = {en}
}
@article{WilhelmFalesTusaetal.1987,
  author    = {Wilhelm, Gernot and Fales, M. and Tusa, S. and Zaccagnini, C.},
  title     = {T. Karrāna 3, T. Ǧīkān and T. Ḫirbat Ṣālih: 1st Campaign},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-85823},
  year      = {1987},
  abstract  = {no Abstract available},
  subject      = {Alter Orient},
  language  = {en}
}
@article{DickneiteSchorlemmerSedlaceketal.1987,
  author    = {Dickneite, G. and Schorlemmer, H. U. and Sedlacek, H. H. and Falk, W. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.},
  title     = {Suppression of macrophage function and prolongation of graft survival by the new guanidinic-like structure, 15-deoxyspergualin},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86991},
  year      = {1987},
  abstract  = {No abstract available.},
  subject      = {Makrophage},
  language  = {en}
}
@article{Scheer1987,
  author    = {Scheer, Ulrich},
  title     = {Structure of lampbrush chromosome loops during different states of transcriptional activity as visualized in the presence of physiological salt concentrations},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39304},
  year      = {1987},
  abstract  = {Lampbrush chromosomes of amphibian oocytes were isolated in the presence of near-physiological salt concentrations, to preserve their native state, and studied by electron microscopy of ultrathin s~dions. The transcriptional state of the lampbrush chromosomes was experimentally modulated by incubating the oocytes for various time periods in medium containing actinomycin D. The observations show that the structure of the lateral loops changes rapidly in response to alterations in transcriptional activity. During decreasing transcriptional activity and reduced packing density of transcripts, the chromatin axis first condensed into nucleosomes and then into an approximately 30 nm thick higher order chromatin fiber. Packaging of the loop axis into supranucleosomal structures may contribute to the foreshortening and retraction of the loops observed during inhibition of transcription and in later stages of meiotic prophase. The increasing packing density of the DNA during the retraction process of the loops could also be visualized by immunofluorescence microscopy using antibodies to DNA. The dependence of the loop chromatin structure on transcriptional activity is discussed in relation to current views of mechanisms involved in gene activation.},
  language  = {en}
}
@article{BuesserLutz1987,
  author    = {B{\"u}sser, M. T. and Lutz, Werner K.},
  title     = {Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-60908},
  year      = {1987},
  abstract  = {In order to investigate whether the Stimulation of liver DNA synthesis might be used to detect one class of hepatic tumor promoters, the incorporation of orally administered radiolabelled thymidine into liver DNA was detennined in rats and mice 24 h after a single oral gavage of test compounds at various dose Ievels. Three DNA-binding hepatocarcinogens, aflatoxin B1; benzidine and carbon tetrachloride, did not stimulate but rather inhibited DNA synthesis (not for CCla). Four hepatic tumor promoters, clofibrate, DDT, phenobarbital and thioacetamide, gave rise to a Stimulation in a dosedependent manner. Single oral doses between 0.02 and 0.3 mmol/kg were required to double the level of thymidine incorporation into liver DNA (= doubling dose, DD). Differentes between species or sex as obsprved in long-term carcinogenicity studies were reflected by a different stimulation of liver DNA synthesis. In agreement with the bioassay data, aldrin was positive only in male mice (DD = 0.007 mmol/kg) but not in male rats or female mice. 2,3, 7,8-TCDD was positive in male mice (DD = 10\(^{-6}\) mmol/kg) andin female rats (DD = 2 x 10\(^{-6}\) mmol/kg) but not in male rats. The assay was also able to distinguish between structural isomers with different carcinogenicities. [alpha]Hexachlorocyclohexane stimulated Iiver DNA synthesis with a doubling dose of about 0.2 mmol/kg in male rats whereas the [gamma]isomer was ineffective even at l mmol/kg. So far, only one result was inconsistent with carcinogenicity bioassay data. The different carcinogenicity of di(2-ethylhexyl)adipate (negative in rats) and di(2-ethylhe.xyl)phthalate (positive) was not detectable. 8oth plasticizers were positive in.this short-term system with DD's of 0. 7 mmol/kg for DEHA and 0.5 mmol/kg for DEHP. The proposed assay is discussed as an attempt to devise short-term assays for carcinogens not detected by the routine genotoxicity test systems.},
  subject      = {Toxikologie},
  language  = {en}
}
@article{PressleyCarigliaBullDeaneetal.1987,
  author    = {Pressley, Michael and Cariglia-Bull, Teresa and Deane, Shelley and Schneider, Wolfgang},
  title     = {Short-term memory, verbal competence, and age as predictors of imagery instructional effectiveness},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62046},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Psychologie},
  language  = {en}
}
@inproceedings{SagelsdorffLutz1987,
  author    = {Sagelsdorff, P. and Lutz, Werner K.},
  title     = {Sensitivity of DNA and nucleotides to oxidation by permanganate and hydrogen peroxide},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-80062},
  year      = {1987},
  abstract  = {no abstract available},
  subject      = {Toxikologie},
  language  = {en}
}
@article{MarreHacker1987,
  author    = {Marre, R. and Hacker, J{\"o}rg},
  title     = {Role of S and common type I-fimbriae of Escherichia coli in experimental upper and lower urinary tract infection},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-59468},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Infektionsbiologie},
  language  = {en}
}
@article{KorthMuellerSustmannetal.1987,
  author    = {Korth, H.-G. and M{\"u}ller, W. and Sustmann, R. and Christl, Manfred},
  title     = {Rearrangement of Free Radicals, XII. ESR Spectroscopic Study of the Ring Opening of the Homobenzvalenyl Radical},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-58376},
  year      = {1987},
  abstract  = {Abstraction of an allylic hydrogen atom in homobenzvalene (4) either in solurion by photolyticaßy generated tert-butoxyl radicals or in an adamantane matrix by X-rays produces the homobcnzvalenyl radical (5). which tbennally rearranps · to tbe tropylium ndical (1). In solution tbe activation cnergy for the rate determined step of the reaction sequence was detennined· to be 13.4 ± O.S kcal/mol.},
  subject      = {Organische Chemie},
  language  = {en}
}
@inproceedings{Lutz1987,
  author    = {Lutz, Werner K.},
  title     = {Quantitative evaluation of DNA-binding data in vivo for low-dose extrapolations},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-80079},
  year      = {1987},
  abstract  = {no abstract available},
  subject      = {Toxikologie},
  language  = {en}
}
@article{FeuersteinLeaderSirenetal.1987,
  author    = {Feuerstein, G. and Leader, P. and Sir{\´e}n, Anna-Leena and Braquet, P.},
  title     = {Protective effect of PAF-acether antagonist, BN 52021, in trichothecen toxicosis},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63244},
  year      = {1987},
  abstract  = {Trichothecenes are mycotoxins which produce Iethai toxicosis in humans and animals, yet no adequate therapeutic regimen has been developed. This study provides evidence that the selective platelet activating factor (PAF) antagonist, BN 52021 (5-15 mg/kg i.v.) can prolong the survival of conscious rats exposed to a highly Iethai T -2 toxicosis. These data also suggest that P AF is an important mediator of this unique toxicosis.},
  subject      = {Neurobiologie},
  language  = {en}
}
@article{GrilliLutzParodi1987,
  author    = {Grilli, S. and Lutz, Werner K. and Parodi, S.},
  title     = {Possible implications from results of animal studies in human risk estimations for benzene: nonlinear dose-response relationship due to saturation of metabolism},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-60936},
  year      = {1987},
  abstract  = {To date, all risk assessment studies on benzene have been based almost exclusively on epiderniological data. Wehave attempted a more integrated and quantitative evaluation of carcinogenic risk for hurnans, trying to utilize, in addition to the epidemiological data, all data available, specifically data on metabolism, genotoxicity, and carcinogenicity in small rodents. An integrated evaluation of the globality of the available data seems to suggest a progressive saturation of metabolic capacity both for man and rodents between 10 and 100 ppm. The most susceptible target cells seem tobe different in humans (predominant induction of myelogenous leukemia) and small rodents (induction of a wide variety of tumors). Nevertheless, both epidemiological and experimental carcinogenicity data tend to indicate a flattening ofthe response for the highest dosages, again suggesting a general Saturation of mechanisms of metabolic activation, extended to different target tissues. From a quantitative point of view, the data suggest a carcinogenic potency at 10 ppm two to three times higher than that computable by a linear extrapolation from data in the 100 ppm range. These observations are in accord with the recent proposal of the European Economic Community of reducing benzene time-weighted average occupationallevels from 10 to 5 ppm.},
  subject      = {Toxikologie},
  language  = {en}
}
@article{KekowUlrichsMuellerRuchholtzetal.1987,
  author    = {Kekow, J. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W. and Gross, WL},
  title     = {Pancreas transplantation: a study of insulin secretion in isolated islets of Langerhans and in sera using a new enzyme-linked immunosorbent assay},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45229},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Chirurgie},
  language  = {en}
}
@misc{FeuersteinSiren1987,
  author    = {Feuerstein, G. and Sir{\´e}n, Anna-Leena},
  title     = {Opioid peptides: A role in hypertension? [Brief Review]},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63262},
  year      = {1987},
  abstract  = {This review is an attempt to highlight evidence that may implicate the endogenaus opioid system in the pathogenesis of hypertension in humans. The evidence raised includes biochemical, physiological, pharmacological, and behavioral studies con~ucted in in vitro andin vivo systems, experimental models of hypertension, and hornans with essential hypertension. While the compelling biochemical and pharmacological evidence in experimental animals clearly shows the presence of opioid peptides and their receptors in strategic sites of cardiovascular control and potent cardiovascular response to opioid peptides, opioid antagonists show no consistent blockade or reversal of hypertension in experimental animals or humans. One possible explanation for this phenomenon could be the vast redundancy in systems regulating blood pressure (i.e., the blockade ofone system stillleaves many other systerils fully able to rapidly offset the eliminated system). Regarding the opioid system, the situation is much more complex, since some opioid receptors (\(\mu\)-type) niediate pressor responses, while other receptors (\(\kappa\)type) mediate depressor responses. Therefore, nonselective opioid receptor antagonists (e.g., naloxone), which block both types ofreceptors, can be devoid ofany cardiovascular activity, while a selective \(\mu\)-receptor antagonist or a selective arid potent \(\kappa\)-receptor agonist may produce the desired antihypertensive elfect. A combination of both actions (i.e., a drug that is both \(\mu\)antagonist and a \(\kappa\)antagonist) might be even more advantageous. Until such compounds are developed, this hypothesis will be hard to prove.},
  subject      = {Neurobiologie},
  language  = {en}
}
@article{SchmollHackerGoebel1987,
  author    = {Schmoll, T. and Hacker, J{\"o}rg and Goebel, W.},
  title     = {Nucleotide sequence of the sfaA gene coding for the S fimbrial protein subunit of Escherichia coli},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-59480},
  year      = {1987},
  abstract  = {The sfaA gene of the uropathogenic Escherichia coli 06 strain 536, which is responsible for the determination of the S fimbrial protein subunit, was sequenced. The structural gene codes for a polypeptide of 180 amino acids including a 24-residue N-terminal signal sequence. A size of 15.95 kDa was calculated for the processed SfaA protein. The nucleotide and deduced amino acid sequences show significant homology to those of the F1C fimbria and, to a lesser extent, of the mannose- sensitive hemagglutinating fimbria (FimA, PilA). Only week homology toP fimbriae subunits (F72 , Pap) was found.},
  subject      = {Infektionsbiologie},
  language  = {en}
}
@article{FluegelRethwilmMaureretal.1987,
  author    = {Fl{\"u}gel, Rolf M. and Rethwilm, Axel and Maurer, Bernd and Darai, Gholamreza},
  title     = {Nucleotide sequence analysis of the env gene and its flanking regions of the human spumaretrovirus reveals two novel genes},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61509},
  year      = {1987},
  abstract  = {Recombinant clonesthat represent the 3' part ofthe genome of the human spumaretrovirus (foamy virus) were established from viral DNA and from DNA complementary to viral RNA. The recombinant clones were characterized by blot hybridizations and nucleotide sequence analysis. The deduced protein sequence of the clones at their 5' ends was found to be homologous to the 3' domain of retroviral reverse transcriptases. Downstream of a small intergerne pol-env region a long open reading frame of 985 amino acid residues was identified that according to its genomic location, size, glycosylation signals, and hydrophobicity protile closely resembles the lentiviral env genes. The spumaretroviral env gene is followed by two open reading frames, termed bel-l and bel-2 which are located between env and the long terminal repeat region. The long terminal repeat of 1259 nucleotides is preceded by a polypurine tract and contains the canonical signal sequences characteristic for transcriptional regulation of retroviruses. The provisional classitication of the spumaretrovirus subfamily is discussed.},
  subject      = {Virologie},
  language  = {en}
}
@article{FluegelMaurerBannertetal.1987,
  author    = {Fl{\"u}gel, Rolf M. and Maurer, Bernd and Bannert, Helmut and Rethwilm, Axel and Schnitzler, Paul and Darai, Gholamreza},
  title     = {Nucleotide sequence analysis of a cloned DNA fragment from human cells reveals homology to retrotransposons},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61525},
  year      = {1987},
  abstract  = {During molecular cloning of proviral DNA of human. spumaretroVirus, various recombinant clones were estabUshed and analyzed. Blot hybridization revealed that one of the recoinbinant plasmids bad the characteristic features of a member of the long interspersed repetitive sequences famlly. The DNA element was analyzed by restrictioil mapping and nuelootide sequencing. It showed a high degree of amino acid sequence homology of 54.3\% when conipared with the 5'-terminal part of the pol gelie product of the murine retrotransposon LIMd. The 3' region of the cloned DNA element encodes proteins witb an even higher degree of homology of 67.4\% in comparison to the corresponding parts of a member of the primate Kpnl sequence family.},
  subject      = {Virologie},
  language  = {en}
}
@article{MaschwitzFialaDolling1987,
  author    = {Maschwitz, U. and Fiala, Brigitte and Dolling, W. R.},
  title     = {New trophobiotic symbioses of ants with South East Asian bugs},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-34030},
  year      = {1987},
  abstract  = {A trophobiotic relationship between two species of phloem-feeding plataspid bugs and an ant, Meranoplus mucronatus, was discovered on tree trunks in Malaysia. Similar relationships were found between coreid bugs and Crematogaster sp. and Anoplolepis longipes, on bamboo in the same area. The ants recruit to groups of the bugs and feed on the liquid, sugar-rich faeces of the larvae, stimulating release of the honeydew by tactile signals. They protect all stages of the bugs from disturbance by biting and by the use of defensive secretions. Phloem-feeding bugs in the families Plataspidae and Coreidae need long sty lets to pierce the thick bark of their host tree. The different methods of accommodating the resting stylets in these two families are described. The plataspids are described as Tropidotylus servus sp. novo and T. minister sp. novo A coreid previously reported in association with M. mucronatus in Malaya is described as Hygia cliens sp. novo The coreids on bamboo were determined as Cloresmus spp. and Notobitus affinis.},
  language  = {en}
}
@article{RethwilmDaraiRoesenetal.1987,
  author    = {Rethwilm, Axel and Darai, G. and R{\"o}sen, A. and Maurer, Bernd and Fl{\"u}gel, Rolf M.},
  title     = {Molecular cloning of the genome of human spumaretrovirus},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61518},
  year      = {1987},
  abstract  = {DNA ofhuman spumaretrovirus (HSRV) was cloned from both cDNA and from viral DNA into phage A and bacterial plasmid vectors. The recombinant plasm.ids harboring viral DNA were characterized by Southern blot hybridization and restriction mapping. Physical maps were constructed from cDNA and found to be colinear with the restriction maps obtained from viral DNA. The recombinant clones isolated contained viral DNA inserts which rangein size from 2.2 kb to 15.4 kb. The recombinant clones allowed to construct a physical map of the complete HSRV provirus of 12.2 kb.},
  subject      = {Virologie},
  language  = {en}
}
@article{ChakrabortyKathariouHackeretal.1987,
  author    = {Chakraborty, Trinad and Kathariou, Sophia and Hacker, J{\"o}rg and Hof, Herbert and Huhle, Burkhard and Wagner, Wilma and Kuhn, Michael and Goebel, Werner},
  title     = {Molecular analysis of bacterial cytolysins},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-40328},
  year      = {1987},
  abstract  = {Results of molecular and pathogenic studies of three different bacterial hemolysins (cytolysins) are presented. These exoproteins derive from the two gram-negative bacteria Escherichia coli and Aeromonas hydrophila and from the gram-positive pathogen Listeria monocytogenes. The hemolysin of E. coli is determined by an 8-kilobase (kb) region that includes four clustered genes (hlyC, hlyA, hlyB, and hlyD). This hemolysin determinant is part either of large transmissible plasmids or of the chromosome. The genes located chromosomally are found predominantly in E. coli strains that can cause pyelonephritis and/or other extraintestinal infections. A detailed analysis of the chromosomal hly determinants of one nephropathogenic E. coli strain revealed the existence of specific, large chromosomal insertions 75 kb and lOO kb in size that carry the hly genes but that also influence the expression of other virulence properties, i.e., adhesion and serum resistance. The direct involvement of E. coli hemolysin in virulence could be demonstrated in several model systems. The genetic determinants for hemolysin (cytolysin) formation in , A. hydrophila (aerolysin) and L. monocytogenes (listeriolysin) are less complex. Both cytolysins seem to be encoded by single genes, although two loci (aerB and aerC) that affect the expression and activity of aerolysin have been identified distal and proximal to the structural gene for aerolysin (aerA). Cytolysin-negative mutants of both bacteria were obtained by site-specific deletion and/or transposon mutagenesis. These mutants show a drastic reduction in the virulence of the respective bacteria.},
  language  = {en}
}
@incollection{ShephardSchlatterLutz1987,
  author    = {Shephard, S. E. and Schlatter, C. and Lutz, Werner K.},
  title     = {Model risk analysis of nitrosatable compounds in the diet as precursors of potential endogenous carcinogens},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86188},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  year      = {1987},
  abstract  = {The potential health risk posed by the endogenous formation of N-nitroso compounds (NOC) from nitrosation of dietary ureas, guanidines, amides, amino acids and amanes (primary, secondary and aromatic) was estimated according to the model: Risk = ( daily intake of precursor] X (gastric concentration of nitrite ]n X [nitrosatability rate constant] X [cilrcinogenicity of derivative]. The daily intakes ofthese compound classes span five orders ofmagnitude (100 g/day amides, top; 1-10 mg/day secondary amines, ureas, bottom); the nitrosation rate constants span seven orders of magnitude (aryl amines, ureas, top; amides, secondary amines, bottom); and the carcinogenicity estimates span a 10 000-fold range from 'very strong' to 'virtually noncarcinogenic'. The resulting risk estimates likewise span an enormous range (nine orders of magnitude ): dietary ureas and aromatic amines combined with high nitrite concentration could pose as great a risk as the intake of preformed N-nitrosodimethylamine in the diet. In contrast, the risk posed by the in-vivo nitrosation of primary and secondary amines is probably negligible. The risk contributed by amides (including protein), guanidines and primary amino acids is intermediate between these two extremes.},
  subject      = {Risikoanalyse},
  language  = {en}
}
@article{KleenePfannerPfalleretal.1987,
  author    = {Kleene, R. and Pfanner, N. and Pfaller, R. and Link, T. A. and Sebald, Walter and Neupert, W. and Tropschug, M.},
  title     = {Mitochondrial porin of Neurospora crassa: cDNA cloning, in vitro expression and import into mitochondria},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-62566},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Biochemie},
  language  = {en}
}
@article{StopperJonesZimmermann1987,
  author    = {Stopper, Helga and Jones, H. and Zimmermann, U.},
  title     = {Large scale transfection of mouse L-cells by electropermeabilization},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63497},
  year      = {1987},
  abstract  = {Mouse L-cells were transfected by electropenneabilization using the selectable plasmid pSV2-neo which confers resistance to G-418 (Geneticin). 1be DNA concentration used was 1 l'gfml, the field strength was 10 kV fcm, the duration of the pulse was S ~s. Transfeetion yield was optimal at a temperature of 4°C when using a time in between consecutive pulses of 1 minute compared to shorter (of the order of seoonds) or Ionger (3 minutes) time intervals. A more detailed study of the relationship between the number of pulses applied (up to 10) and transfection yield showed it to be almost linear in this range at 4 o C. The yield of transfectants in response to 10 pulses was up to 1000 per 106 cells (using 3.3 pg DNA per cell). The inßuence of the growth phase of the cells on the transfection yield and I or the subpopulation of the mouse L--ceU line used was shown. Furthennore the clone yield depended on the DNA per ceU ratio within a very small range.},
  subject      = {Toxikologie},
  language  = {en}
}
@article{SchneiderSchauliesSchimplWecker1987,
  author    = {Schneider-Schaulies, J{\"u}rgen and Schimpl, A. and Wecker, E.},
  title     = {Kinetics of cellular oncogene expression in mouse lymphocytes II. Regulation of c-fos and c-myc gene expression},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-54823},
  year      = {1987},
  abstract  = {Newly isolated lymphocytes from mousespleensexpress the c-fos oncogene even in the absence of mitogen with maximal mRNA levels 60 min post preparation of single cell suspension, whereas c-myc mRNA Ievels increase only after mitogenic Stimulation with maximal mRNA Ievels 6 h post Stimulation. The half-lives of c-fos mRNA are generally very short; they increase from 14 min (after 30 min of culture) to 70 min (after 2 h of culture). The half-lives of c-myc mRNA decrease from 50 min (at 2 and 6 h post stimulation with concanavalin A) to 12 min (at 48 h post stimulation). The c-fos gene transcription is already tumed on in time-0 lymphocytes 10 min after disruption of the organ structure of the spleens and is down-regulated after 2 h and later. In nuclear run-on experiments with nonstimulated lymphocytes there is already significant transcription of the first exon of c-myc, but almost no elongation of the transcript to exon 2 and 3. In concanavalin A-treated lymphocytes elongation is stimulated about 5-fold within 6 h and returns to background levels at 48 h post Stimulation. · The nuclear run-on analyses of nonactivated lymphocytes showed a signal for RNA complementary to c-myc mRNA detected with a probe specific for the exon 1/intron 1 boundary of c-myc, which disappeared with increasing time of concanavalin A Stimulation. This anti-sense transcription may play a role in regulating the elongation of cmyc transcripts.},
  subject      = {Lymphozyt},
  language  = {en}
}
@article{FoersterSchartl1987,
  author    = {Foerster, Wolfgang and Schartl, Manfred},
  title     = {Karyotype and isozyme patterns of five species of Aulonocara REGAN, 1922},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86774},
  year      = {1987},
  abstract  = {No abstract available.},
  subject      = {Aulonocara},
  language  = {en}
}
@inproceedings{MochHoschuetzkyHackeretal.1987,
  author    = {Moch, Thomas and Hosch{\"u}tzky, Heinz and Hacker, J{\"o}rg and Kr{\"o}nke, Klaus-D. and Jann, Klaus},
  title     = {Isolation and characterization of the \(\alpha\)-Sialyl-\(\beta\) 2-3-Galactosyl (S)-Specific Adhesin fimbriated Escherichia coli},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-40330},
  year      = {1987},
  abstract  = {The \(\alpha\)-Sialyl-\(\beta\) 2-3-Galactosyl-specific adhesin (S adhesin) was isolated from cells of a recombinant Escherichia coli K-12 strain expressing the S-flmbrial adhesin complex. A crude cell extract was partiaUy dissociated into fimbriae and an adhesin-enriched fraction by heating to 7O°C. From the latter, adhesin was purified to apparent homogeneity (by fast protein liquid chromatography, immunoblot, and NaDodSO\(_4\)/PAGE) by differential ammonium sulfate precipitation, dissociation in 8 M guanidine hydrochloride, and high-resolution anion-exchange chromatography in 8 M urea. The purified adhesin formed an aggregate of M\(_r\)\(\approx\)10\(^6\) that was made up of one type of 12-kDa polypeptide (fimbrillin is 16.5 kDa). It had pI value of 4.7 (fimbriae has a pI value of 6). Adhesin and fimbrillin had different amino add compositions. The purified adhesins agglutinated human and bovine erythrocytes with the same speclfkity as the whole bacteria; purified fimbriae were not adhesive. Monoclonal anti-adhesin and anti-fimbriae antibodies were obtained. Monoclonal antiadhesin, but none of the anti-fimbriae, antibodies inhibited the agglutination of erythrocytes. The anti-adhesive antibodies were used in immuno-gold electron microscopy to localize adhesin exclusively on the fimbriae, with a possible preference to their tips.},
  language  = {en}
}
@article{HackerUlmerFasskeetal.1987,
  author    = {Hacker, J{\"o}rg and Ulmer, E. and Fasske, E. and Schmidt, G.},
  title     = {Isolation and characterization of coliphage Omega18A specific for Escherichia coli O18ac strains},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73001},
  year      = {1987},
  abstract  = {The bactedophage Q18A, specific for Escherichia coli 018ac srrains, was isolated frorn sewage. The results of host range and conjugation experiments showed that the sensitivity of bacteria to the phage is associated with rhe presence of 018ac antigens. With sorne of rhe 018 strains rhe phage Q18A produces clear Iysis on bacterial lawns only when applied at a high multiplicity and moreover the phage does not multiply. With rhe help of the phage Ql8A, E. coli 0 18ac strains could be divided inro rwo serologically clistinct subgroups called 018A and 018A1• E. coli strains belanging to the sugroup 0 ISAare sensitive to phage Q t8A wheteas bacteria of subgroup A1 are resistanr.},
  subject      = {Escherichia coli},
  language  = {en}
}
@article{BoeschFriederichLutzetal.1987,
  author    = {B{\"o}sch, R. and Friederich, U. and Lutz, Werner K. and Brocker, E. and Bachmann, M. and Schlatter, C.},
  title     = {Investigations on DNA binding in rat liver and in Salmonella and on mutagenicity in the Ames test by emodin, a natural anthraquinone},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-60913},
  year      = {1987},
  abstract  = {Emodin (1,6,8-trihydroxy-3-methylanthraquinone), an important aglycone found in natural anthraquinone glycosides frequently used in Iaxative drugs, was mutagenic in the Salmonellajmammalian microsome assay (Ames test) with a specificity for strain TA1537. The mutagenic activity was activationdependent with an optimal amount of S9 from Aroclor 1254-treated male Sprague-Dawley rats of 20\% in the S9 mix (v jv) for 10 p.g emodin per plate. Heat inactivation of the S9 for 30 min at 60 ° C prevented mutagenicity. The addition of the cytochrome P-448 inhibitor 7,8-benzoflavone (18.5 nmoles per plate) reduced the mutagenic activity of 5.0 p.g emodin per plate to about one third, whereas the P-450 inhibitor metyrapone (up to 1850 nmoles per plate) was without effect. To test whether a metabolite" binds covalently to Salmonella DNA, [10-\(^{14}\)C]emodin was radiosynthesized, large batches of bacteria were incubated with [10-\(^{14}\)C]emodin and DNA was isolated. [G- \(^{3}\)H]Aflatoxin B1 (AFB1) was used as a positive control mutagen known to act via DNA binding. DNA obtained after aflatoxin treatment could be purified to constant specific activity. With emodin, the specific activity of DNA did not remain constant after repeated precipitations so that it is unlikely that the mutagenicity of emodin is due to covalent interaction of a metabolite with DNA. The antioxidants vitamin C and E or glutathione did not reduce the mutagenicity. Emodin was also negative with strain TA102. Thus, oxygen radicals are probably not involved. When emodin was incubated with S9 alone for up to 50 h before heat-inactivation of the enzymes and addition of bacteria, the mutagenic activity did not decrease. It is concluded that the mutagenicity of emodin is due to a chemically stable, oxidized metabolite forming physico-chemical associations with DNA, possibly of the intercalative type. In order to check whether an intact mammalian organism might be able to activate emodin to a DNA-binding metabolite, radiolabelled emodin was administered by oral gavage to male SD rats and liver DNA was isolated after 72 h. Very little radioactivity was associated with the DNA. Considering that DNA radioactivity could also be due to sources other than covalent interactions, an upper limit for the · covalent binding index, CBI = (p.moles chemical bound per moles DNA nucleotides)/(mmoles chemical administered per kg body weight) of 0.5 is deduced. This is 104 times below the CBI of AFB1. The demonstration of a lack of covalent interaction with DNA bothin Salmonellaandin rat liver is discussed in terms of a reduced hazard posed by emodin as a mutagenic drug in use in humans.},
  subject      = {Toxikologie},
  language  = {en}
}
@article{MauelerEigenbrodtSchartl1987,
  author    = {Maueler, W. and Eigenbrodt, E. and Schartl, Manfred},
  title     = {Intermediary metabolism of normal and tumorous tissue of Xiphophorus (Teleostei: Poeciliidae)},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61855},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Physiologische Chemie},
  language  = {en}
}
@article{PaakkariSirenNurminenetal.1987,
  author    = {Paakkari, I. and Sir{\´e}n, Anna-Leena and Nurminen, M.-L. and Svartstr{\"o}m-Fraser, M.},
  title     = {Injection of thyrotropin releasing hormone into the locus coeruleus increases blood pressure},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72894},
  year      = {1987},
  abstract  = {Thyrotropin releasing hormone (TRH), 10 pmol kg-1 injected in the region of locus coeruleus, caused a rapid (within 1 min) rise of mean arterial pressure in the urethane- naesthetized rat. No clear-cut effects in heart rate or ventilation were observed. When TRH was injected into the lateral ventricle, a dose more than 10-fold higher was required to achieve a comparable rise in arterial pressure. It is concluded that TRH may have a physiological rote in centrat cardiovascular regulation.},
  subject      = {Thyreotropin-Releasinghormon},
  language  = {en}
}
@article{BenaventeRoseReimeretal.1987,
  author    = {Benavente, Ricardo and Rose, Kathleen M. and Reimer, Georg and H{\"u}gle-D{\"o}rr, Barbara and Scheer, Ulrich},
  title     = {Inhibition of nucleolar reformation after microinjection of antibodies to RNA polymerase I into mitotic cells},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33247},
  year      = {1987},
  abstract  = {The formation of daughter nuclei and the reformation of nucleolar structures was studied after microinjection of antibodies to RNA polymerase I into dividing cultured cells (PtK2). The fate of several nucleolar proteins representing the three main structural subcomponents of the nucleolus was examined by immunofluorescence and electron microscopy. The results show that the RNA polymerase I antibodies do not interfere with normal mitotic progression or the early steps of nucleologenesis, i.e. , the aggregation of nucleolar material into prenucleolar bodies. However,they inhibit the telophasic coalescence of the prenucleolar bodies into the chromosomal nucleolar organizer regions, thus preventing the formation of new nucleoli. These prenucleolar bodies show a fibrillar organization that also compositionally resembles the dense fibrillar component of interphase nucleoli . We conclude that during normal nucleologenesis the dense fibrillar component forms from preformed entities around nucleolar organizer regions, and that this association seems to be dependent on the presence of an active form of RNA polymerase I.},
  language  = {en}
}
@incollection{ShephardHegiLutz1987,
  author    = {Shephard, S. E. and Hegi, M. E. and Lutz, Werner K.},
  title     = {In-vitro assays to detect alkylating and mutagenic activities of dietary components nitrosated in situ},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86194},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  year      = {1987},
  abstract  = {Nitrosation of dietary components has been combined with the 4-(para-nitrobenzyl)pyridine (NBP) colorimetric test for screening alkylating agents and with the Ames test for the detection of mutagenic activity. This allowed the investigation of short-hved nitrosation products of dietary components which generate electrophilic degradation products requiring no metabolic activation (natural amino acids and some derivatives, ureas, guanidines, primary alkyl and aryl amines). In a first system, precursor, nitrous acid and NBP were present simultaneously. All amino acids tested, except glutamic acid and glutamine, gave positive results. The reactivities spanned more than three orders of magnitude, with the aromatic amino acids and methionine the most active; two primary amines, tryptamine and histamine, were also strongly reactive. All guanidines tested, except the amino acid arginine, gave negative results. A second system consisted of two phases: NBP was added only after destruction of residual nitrite and adjustment of the pH to neutrality. This system was useful for the study of ureas, which are stable in acid but not in neutral media. The range of responses covered more than two orders of magnitude. Most amino acids and primary amines also gave positive results, but could be assessed only after analysing the kinetics of the competing reactions and choosing appropriate reaction times. In a third system, Salmonella typhimurium strain TA1OO replaced NBP. Representatives of the class of amino acids, ureas, the primary amine tryptamine, and aniline became higbly mutagenic upon nitrosation. Methylguanidine was only weakly mutagenic under the present assay conditions. The results indicate that further studies with unstable nitrosation products of dietary components are required to understand more thoroughly the role of endogenous nitrosation in gastric cancer.},
  subject      = {Medizin},
  language  = {en}
}
@article{ScheerRaska1987,
  author    = {Scheer, Ulrich and Raska, I.},
  title     = {Immunocytochemical localization of RNA polymerase I in the fibrillar centers of nucleoli},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39618},
  year      = {1987},
  abstract  = {No abstract available},
  language  = {en}
}
@misc{ReimerRaskaTanetal.1987,
  author    = {Reimer, Georg and Raska, Ivan and Tan, Eng M. and Scheer, Ulrich},
  title     = {Human autoantibodies: probes for nucleolus structure and function},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41410},
  year      = {1987},
  abstract  = {No abstract available},
  language  = {en}
}
@article{ScheerMessnerHazanetal.1987,
  author    = {Scheer, Ulrich and Messner, Karin and Hazan, Rachel and Raska, Ivan and Hansmann, Paul and Falk, Heinz and Spiess, Eberhard and Franke, Werner W.},
  title     = {High sensitivity immunolocalization of double and single-stranded DNA by a monoclonal antibody},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41063},
  year      = {1987},
  abstract  = {A monoclonal antibody (AK 30-10) is described which specifically reacts with DNA both in double and single-stranded forms but not with other molecules and structures, including deoxyribonucleotides and RNAs. When used in immunocytochemical experiments on tissue sections and permeabilized cultured cells, this antibody detects DNA-containing structures, even when the DNA is present in very small amounts. Examples of high resolution detection include the DNA present in amplified extrachromosomal nucleoli, chromomeres of lampbrush chromosomes, mitochondria, chloroplasts and mycoplasmal particles. In immunoelectron microscopy using the immunogold technique, the DNA was localized in distinct substructures such as the "fibrillar centers" of nucleoli and certain stromal centers in chloroplasts. The antibody also reacts with DNA of chromatin of living cells, as shown by microinjection into cultured mitotic cells and into nuclei of amphibian oocytes. The potential value and the limitations of immunocytochemical DNA detection are discussed.},
  subject      = {Cytologie},
  language  = {en}
}
@incollection{FalesTusaWilhelmetal.1987,
  author    = {Fales, Frederick Marion and Tusa, Sebastiano and Wilhelm, Gernot and Zaccagnini, Carlo},
  title     = {German-Italian expedition to Iraq: preliminary report on the first campaign of excavations within the Saddam Dam Reservoir Archaeological Rescue Project (1984)},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-78053},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Orientalistik},
  language  = {en}
}
@article{UlrichsNoethlingKelleretal.1987,
  author    = {Ulrichs, Karin and N{\"o}thling, R. and Keller, R. and Heusermann, U. and M{\"u}ller-Buchholtz, W.},
  title     = {Genetically determined variation of constitutive major histocompatibility complex class II antigen expression in various rat strains and cell types},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44769},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Chirurgie},
  language  = {en}
}
@article{SchreckChristl1987,
  author    = {Schreck, Michael and Christl, Manfred},
  title     = {Generation and Interception of 1-Oxa-3,4-cyclohexadiene},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-31601},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Chemie},
  language  = {en}
}
@incollection{LohseKlotzSchwabe1987,
  author    = {Lohse, Martin J. and Klotz, Karl-Norbert and Schwabe, Ulrich},
  title     = {Functional characterization of A1 adenoosine receptors by photoaffinity labelling},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86097},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  year      = {1987},
  abstract  = {The ligand-binding subunit ofthe A1 adenosine receptor has been identified in membranes with the photoaffinity Iabel R-2-azido-N6-p-hydroxyphenylisopropyladenosine (R-AHPIA). Covalent labelling ofthe A1 receptor can also be achieved in intact cells. The dissociation of the radioiodinated label (1251-AHPIA) from isolated rat fat cells was incomplete after UV irradiation, leaving about 20°/o of irreversible specific binding. Such covalent labelling of the receptor led to a concentration-dependent reduction of cellular cyclic AMP levels. This persistent effect of covalent labeHing occurred with an IC50 value of 9 nM, as compared to an IC50 value of 0.9 nM for the direct reduction of cyclic AMP Ievels by the ligand. The difference in the IC5o values can be explained by assuming spare receptors. This hypothesis was verified in binding studies using [ 3HJPIA as a radioligand. R-AHPIA inhibited binding of [3H)PIA to intact fat cells with a K1 value of about 20 nM, which is about 20 tim es high er than the corresponding IC50 value of cyclic AMP reduction. These data show that the A1 receptor is activated according to the occupancy theory. The high sensitivity of the activation in intact ceJis is due to a large number of spare receptors.},
  subject      = {Adenosinrezeptor},
  language  = {en}
}
@article{BarnekowPaulSchartl1987,
  author    = {Barnekow, A. and Paul, E. and Schartl, Manfred},
  title     = {Expression of the c-src protooncogene in human skin tumors},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61870},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Physiologische Chemie},
  language  = {en}
}
@article{DandekarSchulz1987,
  author    = {Dandekar, Thomas and Schulz, R.},
  title     = {Evidence for the expression of peptides derived from three opioid precursors in NG 108CC15 hybrid cells},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29909},
  year      = {1987},
  abstract  = {No abstract available},
  language  = {en}
}
@article{SyldatkAndreeStoffregenetal.1987,
  author    = {Syldatk, C. and Andree, H. and Stoffregen, A. and Wagner, F. and Stumpf, B. and Ernst, L. and Zilch, H. and Tacke, Reinhold},
  title     = {Enantioselective reduction of acetyldimethylphenylsilane by Trigonopsis variabilis (DSM 70714)},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63836},
  year      = {1987},
  abstract  = {Growing and resting cells of the yeast Trigonapsis variabilis (DSM 70714) can be used for the enantioselective reduction of the organosilicon compound acetyldimethylphenylsilane (J) to give optically active (R)-(1-hydroxyethyl)dimethylphenylsilane [(R)-2] in good yields. The enantiomeric purity of the isolated product was determined tobe 62-86\% ee depending on the substrate concentration used. Both substrate and product caused an inhibition of the reaction at concentrations higher than 0.35 and 0.5 g/1, respectively. Besides, higher substrate and product concentrations led to increased formation of the by-product 1,1,3,3-tetramethyl-1,3-diphenyldisiloxane. Considering the limiting substrate and product concentrations, it was possible to use the same biomass at least 5 times without significant loss of enzyme activity. 3-Methyl-3-phenyl-2-butanone (5) and acetyldimethylphenylgermane (7), which represent carbon and germanium analogues of 1, were also found to be accepted as substrates by Trigonapsis variabilis (DSM 70714). The reduction rates of the silicon {1) and germanium compound {7) were much higher than the transformation rate of the corresponding carbon analogue 5.},
  subject      = {Anorganische Chemie},
  language  = {en}
}
@article{ZimmermannStopper1987,
  author    = {Zimmermann, U. and Stopper, Helga},
  title     = {Elektrofusion und Elektropermeabilisierung von Zellen : Eine neuartige Methode der Biotechnologie zur gezieltenVer{\"a}nderung der genetischen Eigenschaften von Zellen},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63514},
  year      = {1987},
  abstract  = {No abstract available},
  subject      = {Toxikologie},
  language  = {en}
}
@incollection{ZimmermannStopper1987,
  author    = {Zimmermann, U. and Stopper, Helga},
  title     = {Electrofusion and electropermeabilization of cells},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-73065},
  publisher      = {Universit{\"a}t W{\"u}rzburg},
  year      = {1987},
  abstract  = {No abstract available.},
  subject      = {Elektrofusion},
  language  = {en}
}
@article{PeschkeMahsberggebKrapfFuldner1987,
  author    = {Peschke, Klaus and Mahsberg [geb. Krapf], Dieter and Fuldner, Dietrich},
  title     = {Ecological separation, functional relationships, and limiting resources in a carrion insect community},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86361},
  year      = {1987},
  abstract  = {1. Thr ecological separation of 19 carrion inscet species (adults and some of their larvae) was investigated at rabbit carcasses in North Bavaria (FRG) referring to 4 niche dimensions. In the (1.) macrohabitats (forest - clearing) the distribution of saprophageous beetle larvae was mainly considered, for (2.) seasonality the differential abundance of blow flies (Colliphoridae). (3.) The stages of decay were correlated with the temperature dependent development of blow fly maggots affecting the abundance of competing saprophageous beetles and of carnivors preying upon maggots of different size classes. By using ( 4.) microhabitats (spatial subdivision of a carcass) as further niche dimension, the dustering of speries using similar food resources was domonstrated in a niche overlap dendrogram. 2. The quantitative effect of predators on blow fly maggots was investigated both in field and laboratory experiments. Predation upon maggots rcduces their scramble competition, resulting in a higher pupal weight. Thus, the reproductive succcss of the blow flies seems to be buffered by the developmental flexibility of the calliphorids. The numerical effect of predators and parasitoids on the blow fly pupae was also quantified. 3. In a case study on the staphylinid beetle, Aleochara curtula, we investigated the diffenntial abundance of sexes. The ratio at which the males and females arrive at the carcass is balanced. Here the beetles feed and copulated. Females depart into the vicinity of the carrion much earlier than males, thus shifting the sex ratio to a maale bias. In the surroundings the females deposit their eggs, and the parasitoid first instar larvae search for scattered blow fly pupae. The temporal and spatial distribution of both sexes of A. curtula is thus not only affected by the food allocation of the adults, but a.lso by limiting resources of mating end egg laying sites as well as larval hosts.},
  subject      = {Aask{\"a}fer},
  language  = {en}
}