@article{RabevanOorschotJentschke2020, author = {Rabe, A. and van Oorschot, B. and Jentschke, E.}, title = {Suizidalit{\"a}t bei Krebspatienten}, series = {Der Onkologe}, volume = {26}, journal = {Der Onkologe}, issn = {Suizidalit{\"a}t bei Krebspatienten}, doi = {10.1007/s00761-020-00712-x}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-232401}, pages = {163-168}, year = {2020}, abstract = {Hintergrund Die Diagnose Krebs und ihre Behandlung kann eine große Belastung f{\"u}r die Betroffenen darstellen. Neben k{\"o}rperlichen Beschwerden kann auch die Psyche in Mitleidenschaft gezogen werden. Fehlt es an entsprechenden Bew{\"a}ltigungsstrategien, kann der selbstbestimmte Tod als einziger Ausweg erscheinen. Ziel und Fragestellung Die vorliegende {\"U}bersichtsarbeit zur Suizidalit{\"a}t bei Krebspatienten befasst sich mit einem Thema, das in der Forschung und Praxis in Deutschland nur wenig Aufmerksamkeit findet. Material und Methoden Eine themenbezogene Literaturrecherche stellt die Basis der Arbeit dar. Ergebnisse Todesw{\"u}nsche unter Krebspatienten sind nicht selten und k{\"o}nnen Suizidgedanken/-absichten beinhalten. Psychische Beschwerden, insbesondere Hoffnungslosigkeit und Depression, sind ernstzunehmende Risikofaktoren. Das Erkennen einer hohen psychischen Belastung/von Todesw{\"u}nschen ist ein wichtiger Aspekt f{\"u}r die Suizidpr{\"a}vention. F{\"u}r die Praxis empfiehlt sich zun{\"a}chst die Verwendung von Frageb{\"o}gen. Bei auff{\"a}lligen Werten muss die Suizidalit{\"a}t proaktiv in einem pers{\"o}nlichen Gespr{\"a}ch exploriert werden. Betroffene sind meist ambivalent bez{\"u}glich ihrer Entscheidung f{\"u}r oder gegen das Leben. Dies stellt eine große Chance f{\"u}r Interventionen dar. Schlussfolgerungen Suizidalit{\"a}t kann verhindert werden, wenn die hohe Belastung erkannt wird. Bereits das Gespr{\"a}ch zwischen Arzt und Patient {\"u}ber Todesw{\"u}nsche kann eine erste Entlastung darstellen.}, language = {de} } @article{HerrmannGlotzbachMuehlbergeretal.2011, author = {Herrmann, Martin J. and Glotzbach, Evelyn and M{\"u}hlberger, Andreas and Gschwendtner, Kathrin and Fallgatter, Andreas J. and Pauli, Paul}, title = {Prefrontal Brain Activation During Emotional Processing: A Functional Near Infrared Spectroscopy Study (fNIRS)}, series = {The Open Neuroimaging Journal}, journal = {The Open Neuroimaging Journal}, doi = {10.2174/1874440001105010033}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-97437}, year = {2011}, abstract = {The limbic system and especially the amygdala have been identified as key structures in emotion induction and regulation. Recently research has additionally focused on the influence of prefrontal areas on emotion processing in the limbic system and the amygdala. Results from fMRI studies indicate that the prefrontal cortex (PFC) is involved not only in emotion induction but also in emotion regulation. However, studies using fNIRS only report prefrontal brain activation during emotion induction. So far it lacks the attempt to compare emotion induction and emotion regulation with regard to prefrontal activation measured with fNIRS, to exclude the possibility that the reported prefrontal brain activation in fNIRS studies are mainly caused by automatic emotion regulation processes. Therefore this work tried to distinguish emotion induction from regulation via fNIRS of the prefrontal cortex. 20 healthy women viewed neutral pictures as a baseline condition, fearful pictures as induction condition and reappraised fearful pictures as regulation condition in randomized order. As predicted, the view-fearful condition led to higher arousal ratings than the view-neutral condition with the reappraise-fearful condition in between. For the fNIRS results the induction condition showed an activation of the bilateral PFC compared to the baseline condition (viewing neutral). The regulation condition showed an activation only of the left PFC compared to the baseline condition, although the direct comparison between induction and regulation condition revealed no significant difference in brain activation. Therefore our study underscores the results of previous fNIRS studies showing prefrontal brain activation during emotion induction and rejects the hypothesis that this prefrontal brain activation might only be a result of automatic emotion regulation processes.}, language = {en} } @article{HerrmannBeierSimonsetal.2016, author = {Herrmann, Martin J. and Beier, Jennifer S. and Simons, Bibiane and Polak, Thomas}, title = {Transcranial Direct Current Stimulation (tDCS) of the Right Inferior Frontal Gyrus Attenuates Skin Conductance Responses to Unpredictable Threat Conditions}, series = {Frontiers in Human Neuroscience}, volume = {10}, journal = {Frontiers in Human Neuroscience}, number = {352}, doi = {10.3389/fnhum.2016.00352}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-146486}, year = {2016}, abstract = {Patients with panic and post-traumatic stress disorders seem to show increased psychophysiological reactions to conditions of unpredictable (U) threat, which has been discussed as a neurobiological marker of elevated levels of sustained fear in these disorders. Interestingly, a recent study found that the right inferior frontal gyrus (rIFG) is correlated to the successful regulation of sustained fear during U threat. Therefore this study aimed to examine the potential use of non-invasive brain stimulation to foster the rIFG by means of anodal transcranial direct current stimulation (tDCS) in order to reduce psychophysiological reactions to U threat. Twenty six participants were randomly assigned into an anodal and sham stimulation group in a double-blinded manner. Anodal and cathodal electrodes (7 * 5 cm) were positioned right frontal to target the rIFG. Stimulation intensity was I = 2 mA applied for 20 min during a task including U threat conditions (NPU-task). The effects of the NPU paradigm were measured by assessing the emotional startle modulation and the skin conductance response (SCR) at the outset of the different conditions. We found a significant interaction effect of condition × tDCS for the SCR (F(2,48) = 6.3, p < 0.01) without main effects of condition and tDCS. Post hoc tests revealed that the increase in SCR from neutral (N) to U condition was significantly reduced in verum compared to the sham tDCS group (t(24) = 3.84, p < 0.001). Our results emphasize the causal role of rIFG for emotional regulation and the potential use of tDCS to reduce apprehension during U threat conditions and therefore as a treatment for anxiety disorders.}, language = {en} } @article{GlotzbachMuehlbergerGschwendtneretal.2011, author = {Glotzbach, Evelyn and M{\"u}hlberger, Andreas and Gschwendtner, Kathrin and Fallgatter, Andreas J and Pauli, Paul and Herrmann, Martin J}, title = {Prefrontal Brain Activation During Emotional Processing: A Functional Near Infrared Spectroscopy Study (fNIRS)}, series = {The Open Neuroimaging Journal}, volume = {5}, journal = {The Open Neuroimaging Journal}, doi = {10.2174/1874440001105010033}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-141714}, pages = {33-39}, year = {2011}, abstract = {The limbic system and especially the amygdala have been identified as key structures in emotion induction and regulation. Recently research has additionally focused on the influence of prefrontal areas on emotion processing in the limbic system and the amygdala. Results from fMRI studies indicate that the prefrontal cortex (PFC) is involved not only in emotion induction but also in emotion regulation. However, studies using fNIRS only report prefrontal brain activation during emotion induction. So far it lacks the attempt to compare emotion induction and emotion regulation with regard to prefrontal activation measured with fNIRS, to exclude the possibility that the reported prefrontal brain activation in fNIRS studies are mainly caused by automatic emotion regulation processes. Therefore this work tried to distinguish emotion induction from regulation via fNIRS of the prefrontal cortex. 20 healthy women viewed neutral pictures as a baseline condition, fearful pictures as induction condition and reappraised fearful pictures as regulation condition in randomized order. As predicted, the view-fearful condition led to higher arousal ratings than the view-neutral condition with the reappraise-fearful condition in between. For the fNIRS results the induction condition showed an activation of the bilateral PFC compared to the baseline condition (viewing neutral). The regulation condition showed an activation only of the left PFC compared to the baseline condition, although the direct comparison between induction and regulation condition revealed no significant difference in brain activation. Therefore our study underscores the results of previous fNIRS studies showing prefrontal brain activation during emotion induction and rejects the hypothesis that this prefrontal brain activation might only be a result of automatic emotion regulation processes.}, language = {en} }