@article{VainshteinSanchezBrazmaetal.2010, author = {Vainshtein, Yevhen and Sanchez, Mayka and Brazma, Alvis and Hentze, Matthias W. and Dandekar, Thomas and Muckenthaler, Martina U.}, title = {The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-67869}, year = {2010}, abstract = {Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, production and manipulations are limiting factors, affecting data quality. The use of customized DNA microarrays improves overall data quality in many situations, however, only if for these specifically designed microarrays analysis tools are available. Results: The IronChip Evaluation Package (ICEP) is a collection of Perl utilities and an easy to use data evaluation pipeline for the analysis of microarray data with a focus on data quality of custom-designed microarrays. The package has been developed for the statistical and bioinformatical analysis of the custom cDNA microarray IronChip but can be easily adapted for other cDNA or oligonucleotide-based designed microarray platforms. ICEP uses decision tree-based algorithms to assign quality flags and performs robust analysis based on chip design properties regarding multiple repetitions, ratio cut-off, background and negative controls. Conclusions: ICEP is a stand-alone Windows application to obtain optimal data quality from custom-designed microarrays and is freely available here (see "Additional Files" section) and at: http://www.alice-dsl.net/evgeniy. vainshtein/ICEP/}, subject = {Microarray}, language = {en} } @article{ArgosDandekar1994, author = {Argos, P. and Dandekar, Thomas}, title = {Delineating the main chain topology of four-helix bundle proteins using the genetic algorithm and knowledge based on the amino acid sequence alone}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33807}, year = {1994}, abstract = {No abstract available}, subject = {Proteine}, language = {en} } @article{DandekarStripeckeGrayetal.1991, author = {Dandekar, Thomas and Stripecke, Renata and Gray, Nicola K. and Goossen, Britta and Constable, Anne and Johansson, Hans E. and Hentze, Matthias W.}, title = {Identification of a novel iron-responsive element in murine and human erythroid \(\delta\)-aminolevulinic acid synthase mRNA}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29929}, year = {1991}, abstract = {No abstract available}, language = {en} } @article{DandekarTollervey1992, author = {Dandekar, Thomas and Tollervey, David}, title = {Mutational analysis of Schizosaccharomyces pombe U4 snRNA by plasmid exchange}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29969}, year = {1992}, abstract = {No abstract available}, language = {en} } @article{DandekarTollervey1991, author = {Dandekar, Thomas and Tollervey, D.}, title = {Thirty-three nucleotides of 5' flanking sequence including the TATA box are necessary and sufficient for efficient U2 snRNA transcription in Schizosaccharomycespombe}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29959}, year = {1991}, abstract = {No abstract available}, language = {en} } @article{DandekarSchulz1987, author = {Dandekar, Thomas and Schulz, R.}, title = {Evidence for the expression of peptides derived from three opioid precursors in NG 108CC15 hybrid cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29909}, year = {1987}, abstract = {No abstract available}, language = {en} } @article{DandekarTollervey1993, author = {Dandekar, Thomas and Tollervey, David}, title = {Identification and functional analysis of a novel yeast small nucleolar RNA}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29850}, year = {1993}, abstract = {No abstract available}, language = {en} } @article{DandekarGramschHoughtonetal.1985, author = {Dandekar, Thomas and Gramsch, Christian and Houghton, Richard A. and Schultz, R{\"u}diger}, title = {Affinity purification of \(\beta\)-endorphin-like material from NG108CC15 cells by means of the monoclonal \(\beta\)-endorphin antibody 3-E7}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29896}, year = {1985}, abstract = {No abstract available}, language = {en} } @article{DandekarTollervey1989, author = {Dandekar, Thomas and Tollervey, David}, title = {Cloning of Schizosaccharomyces pombe genes encoding the U1,U2,U3 and U4 snRNAs}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29919}, year = {1989}, abstract = {No abstract available}, language = {en} } @article{SchultzMetznerDandekaretal.1986, author = {Schultz, R{\"u}diger and Metzner, Katharina and Dandekar, Thomas and Gramsch, Christian}, title = {Opiates induce long-term increases in prodynorphin derived peptide levels in the guinea-pig myenteric plexus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29809}, year = {1986}, abstract = {No abstract available}, language = {en} } @article{DandekarSibbald1990, author = {Dandekar, Thomas and Sibbald, Peter R.}, title = {Trans-splicing of pre-mRNA is predicted to occur in a wide range of organisms including vertebrates}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29798}, year = {1990}, abstract = {No abstract available}, language = {en} } @article{DandekarRibesTollervey1989, author = {Dandekar, Thomas and Ribes, V. and Tollervey, David}, title = {Schizosaccharomyces pombe U4 small nuclear RNA closely resembles vertebrate U4 and is required for growth}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29771}, year = {1989}, abstract = {No abstract available}, language = {en} } @article{DandekarArgos1994, author = {Dandekar, Thomas and Argos, Patrick}, title = {Amiloride-sensitive epithelial Na\(^+\) channel is made of three homologous subunits}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29734}, year = {1994}, abstract = {No abstract available}, language = {en} }