@phdthesis{Irmisch2019,
  author    = {Irmisch, Linda},
  title     = {The role of septins and other regulatory proteins in abscission and midbody fate in C. elegans embryos},
  doi       = {10.25972/OPUS-18324},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-183244},
  school      = {Universit{\"a}t W{\"u}rzburg},
  year      = {2019},
  abstract  = {Abscission marks the last step of cytokinesis and gives rise to two physically separated daughter cells and a midbody remnant. This work studies abscission by examining the extent of the abscission failure in C. elegans septin and ESCRT mutants with the help of the ZF1-degradation technique. The ZF1 technique is also applied to discern a possible role for PI3K during abscission. Lastly, we test the role of proteins required for macroautophagy but not for LC3-associated phagocytosis (LAP) and show that after release into the extracellular space, the midbody is resolved via LAP.},
  subject      = {Zellteilung},
  language  = {en}
}