@article{NiewaldaVoellerEschbachetal.2011,
  author    = {Niewalda, Thomas and V{\"o}ller, Thomas and Eschbach, Claire and Ehmer, Julia and Wen-Chuang, Chou and Timme, Marc and Fiala, Andr{\´e} and Gerber, Bertram},
  title     = {A Combined Perceptual, Physico-Chemical, and Imaging Approach to 'Odour-Distances' Suggests a Categorizing Function of the Drosophila Antennal Lobe},
  series = {PLoS One},
  volume    = {6},
  journal   = {PLoS One},
  number    = {9},
  doi       = {10.1371/journal.pone.0024300},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-133510},
  pages     = {e24300},
  year      = {2011},
  abstract  = {How do physico-chemical stimulus features, perception, and physiology relate? Given the multi-layered and parallel architecture of brains, the question specifically is where physiological activity patterns correspond to stimulus features and/or perception. Perceived distances between six odour pairs are defined behaviourally from four independent odour recognition tasks. We find that, in register with the physico-chemical distances of these odours, perceived distances for 3octanol and n-amylacetate are consistently smallest in all four tasks, while the other five odour pairs are about equally distinct. Optical imaging in the antennal lobe, using a calcium sensor transgenically expressed in only first-order sensory or only second-order olfactory projection neurons, reveals that 3-octanol and n-amylacetate are distinctly represented in sensory neurons, but appear merged in projection neurons. These results may suggest that within-antennal lobe processing funnels sensory signals into behaviourally meaningful categories, in register with the physico-chemical relatedness of the odours.},
  language  = {en}
}