@inproceedings{TrendelenburgSpringScheeretal.1974, author = {Trendelenburg, Michael F. and Spring, Herbert and Scheer, Ulrich and Franke, Werner W.}, title = {Morphology of nucleolar cistrons in a plant cell, Acetabularia mediterranea}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-32213}, year = {1974}, abstract = {The structural organization of transcriptionally active DNA that contains cistrons for precursor molecules of ribosomal RNA is described in positively stained spread preparations from nuclei and nucleoli isolated from the green alga, Acetabularia mediterranea Lmx. These nuclei contain large aggregates of nucleolar subunits in which fibril-covered regions, the putative active cistrons for precursors of ribosomal RNA, alternate with fibril-free intercepts, the "spacers". The length distribution of the different intercepts of this DNA is given, and the pattern is compared with those shown in animal cell systems. The data are discussed in relation to problems of transcription and of amplification of ribosomal RNA genes.}, language = {en} } @inproceedings{FrankeScheer1974, author = {Franke, Werner W. and Scheer, Ulrich}, title = {Pathways of nucleocytoplasmic translocation of ribonucleoproteins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33832}, year = {1974}, abstract = {No abstract available}, language = {en} } @inproceedings{Ellgring1975, author = {Ellgring, Johann Heinrich}, title = {Kommunikation und Schlußfolgerung {\"u}ber nichtsprachliches Verhalten}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-50207}, year = {1975}, abstract = {No abstract available}, subject = {Psychologie}, language = {de} } @inproceedings{TrendelenburgFrankeSpringetal.1975, author = {Trendelenburg, M. F. and Franke, Werner W. and Spring, H. and Scheer, Ulrich}, title = {Ultrastructure of transcription in the nucleoli of the green algae Acetabularia major and A. mediterranea}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33779}, year = {1975}, abstract = {No abstract available}, language = {en} } @inproceedings{FrankeScheer1975, author = {Franke, Werner W. and Scheer, Ulrich}, title = {Biochemical and structural aspects of nucleocytoplasmic transfer of ribonucleoproteins at the nuclear envelope level: facts and theses}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33766}, year = {1975}, abstract = {No abstract available}, language = {en} } @inproceedings{AxelrodGorboulevKutateladzeetal.1976, author = {Axelrod, V. D. and Gorboulev, Valentin G. and Kutateladze, T. V. and Barciszewski, J. and Bayev, A. A.}, title = {The new approach to tRNA primary structure determination : the primary structure of valine tRNA\(^{Val}_{2b}\)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-50920}, year = {1976}, abstract = {The new combination of TLC and high voltage electrophoresis on cooling plate is described.We have applied this technique to study of primary structure of tRNA.Preliminary sequence of baker's yeast tRNA^Val_2b is described. New approach to preparation of large tRNA fragments is demonstrated.}, subject = {RNS}, language = {en} } @inproceedings{ZentgrafScheerFranke1976, author = {Zentgraf, Hanswalter and Scheer, Ulrich and Franke, Werner W.}, title = {On the existence of arrested transcriptional machinery in late stages of avian erythropoiesis}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33696}, year = {1976}, abstract = {No abstract available}, language = {de} } @inproceedings{ScheerTrendelenburgFranke1976, author = {Scheer, Ulrich and Trendelenburg, M. F. and Franke, Werner W.}, title = {Regulation of transcription of ribosomal RNA genes during amphibian oogenesis}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33700}, year = {1976}, abstract = {No abstract available}, language = {en} } @inproceedings{ScheerFranke1976, author = {Scheer, Ulrich and Franke, Werner W.}, title = {Transcriptional complexes of nucleolar genes}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41072}, year = {1976}, abstract = {No abstract available}, language = {en} } @inproceedings{Ellgring1976, author = {Ellgring, Johann Heinrich}, title = {Kommunikatives Verhalten im Verlauf depressiver Erkrankungen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43123}, year = {1976}, abstract = {No abstract available}, language = {de} } @inproceedings{EllgringClarke1976, author = {Ellgring, Johann Heinrich and Clarke, Andrew}, title = {Abtastrate und systematische Verhaltensbeobachtung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43147}, year = {1976}, abstract = {No abstract available}, language = {de} } @inproceedings{EllgringScherer1976, author = {Ellgring, Johann Heinrich and Scherer, K. R.}, title = {Verhaltensanalyse sozialer Interaktion}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43131}, year = {1976}, abstract = {No abstract available}, language = {de} } @inproceedings{HommersSteller1977, author = {Hommers, Wilfried and Steller, Max}, title = {Konfigurale Klassifikation von Delinquenten durch Variablen der Therapiemotivation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43501}, year = {1977}, abstract = {No abstract available}, subject = {Psychologie}, language = {de} } @inproceedings{Hommers1977, author = {Hommers, Wilfried}, title = {Ein Bayes-statistischer Vergleich probabilistischer Modelle f{\"u}r das Entscheidungsverhalten von Schulkindern und Studenten}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44206}, year = {1977}, abstract = {No abstract available}, subject = {Psychologie / Kongress / Zeitschrift}, language = {de} } @inproceedings{FrankeZentgrafScheer1978, author = {Franke, Werner W. and Zentgraf, Hanswalter and Scheer, Ulrich}, title = {Supranucleosomal and non-nucleosomal chromatin configurations}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39447}, year = {1978}, abstract = {A significant contribution to the understanding of chromatin organization was the d iscovery of the nucleosome as a globular repeating unit of the package of DNA (Hewish and Burgoyne, 1973; Woodcock, 1973; Kornberg, 1974; Olins and Olins, 1974; for review see Oudet et al., 1978 a) . In accord with the original definition and in ag reement with most workers in this field of research we identify a nucleosome as a spheric alor slightly oblate gr anular particle 10-13 nm in diameter, containing about 200 base pairs of DNA and two of each of the four his tones H2a, H2b, H3 and H4. It is this structure in which the bulk of the nuclear chroma tin is organized in most eukaryotic cells, with the exception of the dinofl age llates (Rae and Steele, 1977; dinofl agellate DNA, however, c an be packed into nucleosoma l structures in vitro by addition of the appropriate amounts of histones;the same reference). Although it seems clear from the work reported that condensed and transcriptiona lly inactive chroma tin is contained in nucleosomes as the principle for first order p acking of DNA there are two important questions onto which we are focusing in the present study: ( i ) What is the higher order of p a cking present in - and perhaps typical-of - the condensed sta te of chromatin, and (ii) what is the specific form of arrangement of transcriptionally a ctive chromatin?}, language = {en} } @inproceedings{LutzSchlatter1978, author = {Lutz, Werner K. and Schlatter, C.}, title = {Extrapolation of carcinogenicity data to low doses with a dose-response study of the binding of benzo(a)pyrene to rat liver DNA}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-80157}, year = {1978}, abstract = {The binding of tritiated benzo(a)pyrene (BP) to liver DNA of 25 adult male rats (SIV 50) has been determined 50 h after a single intraperitoneal injection of doses between 40 ug/kg and 4; mg/kg. The dose-response relations~ ip is linear up to i mg/kg, shows a sigmoid step towards 2 mg/kg and a shallow linear. slope above that value. TlJe 0 bserved bin ding ranges from 1.7 to 180 nmoles BP per mole DNA phosphate. The non-linearity between 1 and 2 mg/kg could be explained 0):1 the basis of an induction of metabolizing enzymes. A pure1y mathematical extrapolation of therumour incidence from a carcinogenic dose (1 x 40mg/kg for a 20\% hepatoma incidence in newborn mice) to human exposure levels (aboilt 0.1 ug/kg per day) would never have followed a step like the on~ found in our experiments. Our dose-effect study therefore shows how carcinogenitity data could be extrapolated in a biologically founded way to low doses.}, subject = {Toxikologie}, language = {en} } @inproceedings{FrankeScheerTrendelenburgetal.1978, author = {Franke, Werner W. and Scheer, Ulrich and Trendelenburg, Michael F. and Zentgraf, H. and Spring, H.}, title = {Morphology of transcriptionally active chromatin}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41097}, year = {1978}, abstract = {Some decades ago it was noted by cytologists that within the interphase nucleus large portions of the transcriptionally ("genetically," in their terms) inactive chromosomal material are contained in aggregates of condensed chromatin, the "chromocenters," whereas transcriptionally active regions of chromosomes appear in a more dispersed form and are less intensely stained with DNA-directed staining procedures (Heitz 1929, 1932, 1956; Bauer 1933). The hypothesis that condensed chromatin is usually characterized by very low or no transcriptional activity, and that transcription occurs in loosely packed forms of chromatin (including, in most cells, the nucleolar chromatin) has received support from studies of ultrathin sections in the electron microscope and from the numerous attempts to separate transcriptionally active from inactive chromatin biochemically (for references, see Anderson et al. 1975; Berkowitz and Doty 1975; Krieg and Wells 1976; Rickwood and Birnie 1976; Gottesfeld 1977). Electron microscopic autoradiography has revealed that sites of RNA synthesis are enriched in dispersed chromatin regions located at the margins of condensed chromatin (Fakan and Bernhard 1971, 1973; Bouteille et al. 1974; Bachellerie et al. 1975) and are characterized by the occurrence of distinct granular and fibrillar ribonucleoprotein (RNP) structures, such as perichromatin granules and fibrils. The discovery that, in most eukaryotic nuclei, major parts of the chromatin are organized in the form of nucleosomes (Olins and Olins 1974; Kornberg 1974; Baldwin et al. 1975) has raised the question whether the same nucleosomal packing of DNA is also present in transcriptionally active chromatin strands. Recent detailed examination of the morphology of active and inactive chromatin involving a diversity of electron microscopic methods, particularly the spreading technique by Miller and coworkers (Miller and Beatty 1969; Miller and Bakken 1972), has indicated that the DNA of some actively transcribed regions is not packed into nucleosomal particles but is present in a rather extended form within a relatively thin (4-7 nm) chromatin fiber.}, language = {en} } @inproceedings{ClarkeEllgring1978, author = {Clarke, A. H. and Ellgring, Johann Heinrich}, title = {Verfahren zur halbautomatischen Bearbeitung von Videoaufzeichnungen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33750}, year = {1978}, abstract = {No abstract available}, language = {de} } @inproceedings{EllgringClarke1978, author = {Ellgring, Johann Heinrich and Clarke, A. H.}, title = {Verlaufsbeobachtungen anhand standardisierter Videoaufzeichnungen bei depressiven Patienten}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33744}, year = {1978}, abstract = {No abstract available}, language = {de} } @inproceedings{VivianiLutz1979, author = {Viviani, A. and Lutz, Werner K.}, title = {Modulation of the in vivo covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA by selective induction of microsomal and nuclear aryl hydrocarbon hydroxylase activity}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-80132}, year = {1979}, abstract = {The influence of microsomal (mAHH) and nuclear (nAHH) aryl hydrocarbon hydroxylase activity on the covalent binding of t:titiated benzo(a)pyrene to rat liver DNA was evaluated in vivo. Induction ofmAHH was obtained after phenobarbitone treatment (180\% of control), which increased DNA binding to 210\%, but left the nAHH unchanged. mAHH and nAHH were slightly indilced with dieldrin (130\% and 120\%), but the binding remairred unchanged. The increasing effect of mAHlt as weil as the possibly decreasing effect of nAHH induction on the binding became obvious when the data of 11 individual rats were used to solve the equation Binding = aX(mAHH) + bX(nAHH) + c. Multiple linear regression analysis resulted in positive values for a and c, a negative value for b, and a multiple correlation coefficient R = 0.82. An influence of other enzymes involved in the metabolism of benzo(a)pyrene cannot be excluded. The Study shows clearly that the binding of a foreign compound to DNA in vivo is not only dependent on microsomal enzyme activities but also on nuclear activities even if the latter are considerably lower than those of mic'rosomes.}, subject = {DNA}, language = {en} } @inproceedings{Krueger1979, author = {Kr{\"u}ger, Hans-Peter}, title = {Die Selbst- und Fremdbeurteilung als Resultante sozialer Erfahrung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86039}, year = {1979}, abstract = {No abstract available}, subject = {Selbsteinsch{\"a}tzung}, language = {de} } @inproceedings{Ruhe1979, author = {Ruhe, Ernstpeter}, title = {Repetition und Integration: Strukturprobleme des 'Roman de Tristan en prose'}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33610}, year = {1979}, abstract = {No abstract available}, language = {de} } @inproceedings{Ruhe1979, author = {Ruhe, Ernstpeter}, title = {Thesen zum Ende der Gattungsgeschichte des h{\"o}fischen Romans}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33626}, year = {1979}, abstract = {No abstract available}, language = {de} } @inproceedings{Krueger1980, author = {Kr{\"u}ger, Hans-Peter}, title = {Selbst- und Fremdbeurteilung in Diagnostik und Psychotherapie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-40964}, year = {1980}, abstract = {No abstract available}, language = {de} } @inproceedings{KruegerKohnen1980, author = {Kr{\"u}ger, Hans-Peter and Kohnen, Ralph}, title = {Evaluierung gruppentherapeutischer Situationen durch physiologische Parameter und Selbsteinsch{\"a}tzungen}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-40971}, year = {1980}, abstract = {No abstract available}, language = {de} } @inproceedings{Hommers1980, author = {Hommers, Wilfried}, title = {Recht und Psychologie - Ein wechselseitiges Verh{\"a}ltnis}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43938}, year = {1980}, abstract = {Traditionally psychological research had assisted (de lege lata and de lege ferenda) jurisdiction, legislation, and law enforcement. However, the fol1owing three examp1es support the thesis that certain areas of psycho1ogica1 research gain new concepts and hypotheses by considering re1ated juristic thought. First, a developmenta1 study on the judgment about neg1igent damages suggested a three-step deve10pment of the evaluation of neg1igence. That threestep development wou1d contradict Heider's sequence of responsibi1ity levels. Second, a cognitive algebra approach to asses the chi1d's understanding of the duty to compensate the victim for his 1055 caused by a culpab1e actor suggested a two-step deve10pment of understanding that duty. The chi1d of the first deve10pment a1 step wou1d regard giving on1y half compensation of the 10ss as doing his duty to repair damages. Third, the concept of cul pa and the "Strafzumes sungs 1 ehre" in the German juri 5 ti c thought are d i scussed as key concepts for innovating psycho1ogica1 research on a moral algebra. Insofar juristic thought proved to assist psycho1ogica1 theory bui1ding what would make the relation of juristic thought and psycho1ogy a relation of interdependence.}, language = {de} } @inproceedings{KruegerRausche1980, author = {Kr{\"u}ger, Hans-Peter and Rausche, A.}, title = {Die Pr{\"u}fung von Verlaufskurven auf das Vorliegen von Trends {\"u}ber die exakte Verteilung von Spearman's S}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-79827}, year = {1980}, abstract = {no abstract available}, subject = {Psychologie}, language = {de} } @inproceedings{KruegerKohnen1981, author = {Kr{\"u}ger, Hans-Peter and Kohnen, Ralph}, title = {Kognitive, emotionale und physiologische Determinanten sozialer Zust{\"a}nde}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86055}, year = {1981}, abstract = {The psychological and physiological effects of a socially oriented sensitivity training were evaluated. It is shown that decreased physical distance as well as increased intimacy yields high activation, both in psychological measures (experienced stress) and in pulse frequences. One result (highly significant and replicated in other experiments) was paradoxical: when Ss had to caress the face of a heterosexual vis-a-vis, they reported high experienced stress, but pulse frequences dropped rapidely below the resting pulse. Some suggestions are made to explain these findings. The question arises whether an autonomic somatic process, induced by social Stimulation, but independent of the cognitive coping is responsible for these results.}, subject = {Psychologie}, language = {de} } @inproceedings{SchartlSchartlAnders1981, author = {Schartl, A. and Schartl, Manfred and Anders, F.}, title = {Phenotypic conversion of malignant melanoma to benign melanoma and vice versa in Xiphophorus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86662}, year = {1981}, abstract = {No abstract available.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @inproceedings{AndersSchollSchartl1981, author = {Anders, F. and Scholl, E. and Schartl, Manfred}, title = {Environmental and hereditary factors in the causation of neoplasia, based on studies of the Xiphophorus fish melanoma system}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86402}, year = {1981}, abstract = {Neoplasia in Xiphophorus can be classified into: a) a Jarge group triggered by carcinogens; b) a large group triggered by promoters; and c) a small group that develops "spontaneously" according to Mendelian Jaw. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Interpopulational arid interracial hybridization is the most effective process that Ieads to disintegration of the protective gene systems. Environmental factors may complete disintegration in somatic cells and thus may trigger neoplasia. The applications of the findings on Xiphophorus to humans are discussed.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @inproceedings{AndersSchartlScholl1981, author = {Anders, F. and Schartl, Manfred and Scholl, E.}, title = {Evaluation of environmental and hereditary factors in carcinogenesis, based on studies in Xiphophorus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72741}, year = {1981}, abstract = {Neoplasia in Xiphophorus can be classified into a) a large group that is triggered by carcinogens; b) a large group triggered by promoters; c) a small group that develops "spontaneously" following interpopulational and interracial hybridizations; and d) a small group that develops "spontaneously" following germ line mutation. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Hybridization is the most effective process that leads to disintegration of the protection gene systems. Environmental factors may complete disintegration and thus may trigger neoplasia. It is discussed whether the findings on Xiphophorus may also apply to humans.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @inproceedings{KohnenKrueger1981, author = {Kohnen, Ralph and Kr{\"u}ger, Hans-Peter}, title = {Soziale Situationen als experimentelle Bedingungen der Pharmakopsychologie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86041}, year = {1981}, abstract = {Summary (Social Situations as Experimental Conditions in Psychopharmacology): To reduce a great variability of drug effects in healthy subjects, stress conditions are used often in pharmacopsychology. However, empirical results show that the desired stress effects are failing. This paper suggests to realize social stress Situations as interactions between subjects, expecting higher challenging effects than experimentator-subject-interactions, usually used in experimental designs. Two experimental studies are reported: the call-upsituation and the group-therapy situation. The experimental effects were measured by changes of pulse-frequencies. The results indicate that in the two situations high and low dosages of tranquilizing drugs lead to comparable (and so predictable) effects only, if a Situation is high challenging for the experimental subjects. The call-up situation, which proves performance, challenges male subjects highly. The emotional or social competence demanding group-therapy situation is a high challenging situation for warnen. It is concluded that no situation is stressing a person generally. Depending from personality characteristics, differential stressor effects appear. Consequences for experiments in pharmacopsychology are discussed.}, subject = {Soziale Situation}, language = {de} } @inproceedings{KruegerKohnenLienert1981, author = {Kr{\"u}ger, Hans-Peter and Kohnen, Ralf and Lienert, Gustav A.}, title = {Drei Forderungen zur Pr{\"u}fung der Homogenit{\"a}t von Zentren bei Multicenter-Studien}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-101730}, year = {1981}, abstract = {Es wird argumentiert, daß bei der Pr{\"u}fung der Homgenit{\"a}t von Zentren in mehrfaktoriellen Multicenter-Studien vor allem entscheidend ist, daß sich die Zentren in den faktoriellen Variablen nicht unterscheiden, deren Effekte in der sp{\"a}teren Auswertung interpretiert werden sollen. Dazu wird folgendes Procedere vorgeschlagen: (1) {\"u}berpr{\"u}fe, ob in allen Zentren die Randomisierungsbedingungen eingehalten wurden, (2) {\"u}berpr{\"u}fe, ob die Zentren homogen bezogen auf die eingebrachten Schichtvariablen (z.B. Geschlecht, Indikation) sind und (3) {\"u}berpr{\"u}fe, ob die Zentren homogen sind bezogen auf die Wechselwirkungen zwischen den eingebrachten faktoriellen Variablen. Es wird gezeigt, daß vor allem Forderung (3) f{\"u}r die Interpretationsf{\"a}higkeit der Ergebnisse von entscheidender Bedeutung ist. M{\"o}glichkeiten der statistischen Pr{\"u}fung dieser Voraussetzungen werden an einem Beispiel aus der klinischen Pr{\"u}fung eines Psychopharmakons vorgestellt.}, subject = {Psychologie}, language = {de} } @inproceedings{Ellgring1981, author = {Ellgring, Johann Heinrich}, title = {Entwicklungen in video-unterst{\"u}tzter Diagnostik und Therapie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-42127}, year = {1981}, abstract = {No abstract available}, language = {de} } @inproceedings{ClarkeWagnerEllgring1981, author = {Clarke, A. H. and Wagner, H. and Ellgring, Johann Heinrich}, title = {Eine syntaktische Analyse von Sprechen und Blickverhalten bei dyadischer Interaktion}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-42093}, year = {1981}, abstract = {No abstract available}, language = {de} } @inproceedings{EllgringWinkler1981, author = {Ellgring, Johann Heinrich and Winkler, Barbara}, title = {Codierung und Analyse der Sprachinhalte klinischer Interviews}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46273}, year = {1981}, abstract = {No abstract available}, language = {de} } @inproceedings{Scheer1982, author = {Scheer, Ulrich}, title = {Electron microscopic analysis of chromatin and gene expression}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-39456}, year = {1982}, abstract = {No abstract available}, language = {en} } @inproceedings{Hommers1983, author = {Hommers, Wilfried}, title = {Urteilsbildung : Entwicklung der Informationen-Integration im Urteil}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43497}, year = {1983}, abstract = {No abstract available}, subject = {Psychologie}, language = {de} } @inproceedings{Hommers1983, author = {Hommers, Wilfried}, title = {Zur quantitativen Theorie von Wiedergutmachungskognitionen unter Gewinnung ihrer Merkmale aus der Jurisprudenz}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43519}, year = {1983}, abstract = {Grundz{\"u}ge des rechtswissenschaftlichen Gedankenguts zur Schadenswiedergutmachung werden psychologischen Ans{\"a}tzen dazu gegen{\"u}bergestellt. Das Ergebnis ist die Feststellung, daß die stimulusbezogene Urteilsrelevanz der Schadenswiedergutmachung nicht in der psychologischen Forschung ber{\"u}cksichtigt wurde. Ein diesbez{\"u}glicher Untersuchungsansatz sollte sechs Merkmale besitzen: multifaktoriell, multivariat, Stimulus-Response-vergleichend, quantitativ, ontogenetisch und individual-diagnostisch. Er bildet den Prototyp eines die Moral positiver und negativer Akte umfassenden Ansatzes zur moralischen Urteilsbildung, des ses erste Ergebnisse beschrieben werden.}, subject = {Psychologie}, language = {de} } @inproceedings{Ellgring1983, author = {Ellgring, Johann Heinrich}, title = {Spezifische Signalsysteme in der menschlichen Interaktion}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-50212}, year = {1983}, abstract = {Nonverbal communicative behaviours are associated with affective states in a way specific to the individual. This result emerged from longitudinal studies on depressed patients. From the analysis of various nonverbal behaviours it can be concluded that the depressed state is indicated by nonverbal elements in a logical "or-" rather than "and-connection" or in a hierarchical way. It is maintained that the relationship of psychological relevant states (mood) and nonverbal behaviour needs to be studied by intra-individual comparisons to reveal the specifically close relationships effective in everyday communication. With regard to the pragmatic aspect of communication, elements in the nonverbal signalling system seem to possess different levels of generality. However, from decoding studies it can be shown that even very subtle behavioural differences can be detected by an observer. Thus specific signals can become effective in interaction given a familiarity with the idiosyncratic usage.}, subject = {Psychologie}, language = {de} } @inproceedings{ScheerRose1984, author = {Scheer, Ulrich and Rose, Kathleen M.}, title = {Localization of RNA polymerase I in interphase cells and mitotic chromosomes by light and electron microscopic immunocytochemistry}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33223}, year = {1984}, abstract = {Rabbit antibodies to RNA polymerase I from a rat hepatoma have been used to localize the enzyme in a variety of cells at the light and electron microscopic level. In interphase cells the immunofluorescence pattern indicated that polymerase I is contained exclusively within the nucleolus. That this fluorescence, which appeared punctated rather than uniform, represented transcriptional complexes of RNA polymerase I and rRNA genes was suggested by the observation that it was enhanced in regenerating liver and in a hepatoma and was markedly diminished in cells treated with actinomycin D. Electron microscopic immunolocalization using gold-coupled second antibodies showed that transcribed rRNA genes are located in, and probably confined to, the fibrillar centers of the nucleolus. In contrast, the surrounding dense fibrillar component, previously thought to be the site of nascent prerRNA, did not contain detectable amounts of polymerase I. During mitosis, polymerase I molecules were detected by immunofluorescence microscopy at the chromosomal nucleolus organizer region, indicating that a considerable quantity of the enzyme remains bound to the rRNA genes. From this we conclude that rRNA genes loaded with polymerase I molecules are transmitted from one cell generation to the next one and that factors other than the polymerase itself are involved in the modulation of transcription of DNA containing rRNA genes during the cell cycle.}, language = {en} } @inproceedings{Lutz1984, author = {Lutz, Werner K.}, title = {Structural characteristics of compounds that can be activated to chemically reactive metabolites: use for a prediction of a carcinogenic potential}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-80105}, year = {1984}, abstract = {Many mutagens and carcinogens act via covalent interaction of metabolic intermediates with DNA in the target cell. This report groups those structural elements which are often found to form the basis for a metabolism to such chemically reactive metabolites. ~mpounds which are chemically reactive per se and which do not require metabolic activation form group 1. Group 2 compri~es of olefins and aromatic hydrocarbons where the oxidation via an epoxide can be responsible for the generation of reactive species. Aromatic amines, hydrazines, and nitrosamirres form group 3 requiring an oxidation of a nitrogen atom or of a carbon atom in alpha position to a nitrosated amine. Group 4 compounds are halogenated hydrocarbons which can either give rise to radicals or can form an ·olefin (group 2) upon dehydrohalogenation. Group 5 compounds depend upon some preceding enzymatic activity either not available in the target cell or acting on positions in the molecule which are not directly involved in the subsequent formation of electrophilic atoms. Examples for each group are taken from the "List of Chemieals and Irrdustrial Processes Associated with Cancer in Humans" as compiled by the International Agency for the Research on Cancer, and it is shown that 91\% of the organic carcinogens would have been detected on the basis of structural elements characteristic for group 1-5. As opposed to this very high sensitivity, the specificity ( the true negative fraction) of using this approach as a short-term test for carcinogenicity is shown to be bad because detoxification pathways have so far not been taken into account. These competing processes are so complex, however, that either only very extensive knowledge about pharmacokinetics, stability, and reactivity will be required or that in vivo systems have to be used to predict, on a quantitative basis, the darnage expected on the DNA. DNA-binding experiments in vivo are presented with benzene and toluene to demonstrate one possible way for an experimental assessment and it is shown that the detoxification reaction at the methyl group available only in toluene gives rise to a reduction by at least a factor of forty for the binding to rat liver DNA. This quantitative approach available with DNA-binding tests in vivo, also allows evaluation as to whether reactive metabolites and their DNA binding are always the most important single activities contributing to the overall carcinogenicity of a chemical. With the example of the livertumor inducing hexachlorocyclohexane isomers it is shown that situations will be found where reactive metabolites are formed and DNA binding in vivo is measurable but where this activity cannot be the decisive mode of carcinogenic action. It is concluded that the lack of structural elements known to become potentially reactive does not guarantee the lack of a carcinogenic potential.}, subject = {Toxikologie}, language = {en} } @inproceedings{AndersSchartlBarnekow1984, author = {Anders, Fritz and Schartl, Manfred and Barnekow, Angelika}, title = {Xiphophorus as an in vivo model for studies on oncogenes}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86398}, year = {1984}, abstract = {The capacity of Xiphophorus to develop neoplasia can be formally assigned to a "tumor gene" (Tu), which appears to be a normal part of the genome of all individuals. The wild fish have evolved population-specific and cell type-specific systems of regulatory genes (R) for Tu that protect the fish from neoplasia. Hybridization of members of different wild populations in the laborstory followed by treatment of the hybrids with carcinogens led to disintegration of the R systems permitting excessive expression of Tu and thus resulting in neoplasia. Certain hybrids developed neoplasia even spontaneously. Observations on the genuine phenotypic effect of the derepressed Tu in the early embryo indicated an essential normal function of this oncogene in cell differentiation, proliferation and cell-cell communication. Tu appeared to be indispensable in the genome but may also be present in accessory copics. Recently, c-src, the cellular homolog of the Rous sarcoma virus oncogene v-src, was detected in Xiphophorus. The protein product of c-src, pp60c-src, was identified and then examined by its associated kinase activity. This pp60c-src was found in all individuals tested, but, depending on the genotype, its kinase activity was different. The genetic characters of c-src, such as linkage relations, dosage relations, expression, etc., correspond to those of Tu. From a systematic study which showed that pp60c-src was present in all metazoa tested ranging from mammals down to sponges, we concluded that c-src has evolved with the multicellular organization of animals. Neoplasia of animals and humans is a characteristic closely related to this evolution. Our data showed that small aquariurn fish, besides being used successfully because they are time-, space-, and money-saving systems for carcinogenicity testing, are also highly suitable for basic studies on neoplasia at the populational, morphological, developmental, cell biological, and molecular levels.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @inproceedings{Krueger1984, author = {Kr{\"u}ger, Hans-Peter}, title = {Was ist Sprechen? - objektive Registrierung des Sprechverhaltens im Alltag mit dem Logoport}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-41266}, year = {1984}, abstract = {No abstract available}, language = {de} } @inproceedings{Ellgring1984, author = {Ellgring, Heiner}, title = {Nonverbale Indikatoren des psychischen Befindens}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-42082}, year = {1984}, abstract = {No abstract available}, language = {de} } @inproceedings{Ruhe1984, author = {Ruhe, Ernstpeter}, title = {Der chevalier errant auf enzyklop{\"a}discher Fahrt}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-33722}, year = {1984}, abstract = {No abstract available}, language = {de} } @inproceedings{Ruhe1984, author = {Ruhe, Ernstpeter}, title = {Inventio devenue troevemens: La recherche de la mati{\`e}re au moyen {\^a}ge.}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-36816}, year = {1984}, abstract = {No abstract available}, language = {de} } @inproceedings{Ruhe1984, author = {Ruhe, Ernstpeter}, title = {La peur de la transgression: A propos du Livre d'Enanchet et du Bestiaire d'amours.}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-36841}, year = {1984}, abstract = {No abstract available}, language = {fr} } @inproceedings{Hommers1985, author = {Hommers, Wilfried}, title = {Rechtliche Aspekte der Schadenswiedergutmachung als psychologische Problemstellung: Zum Gegenstand der Rechtspsychologie}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43488}, year = {1985}, abstract = {An rechtsbezogenen empirischen Arbeiten zur Schadenswiedergutmachung kann die echte Wechselseitigkeit im Verh{\"a}ltnis von Recht und Psychologie im Einklang mit Hommers (1981) weiter belegt werden. Da die Psychologie somit nicht nur Hilfsfunktion f{\"u}r die Rechtspflege, sondern die rechtlichen Gedankeng{\"a}nge auch umgekehrt in gewissen Bereichen Hilfsfunktion f{\"u}r die psychologische Theorienbildung besitzen, wird eine hinreichende Gegenstandsdefinition der Rechtspsychologie erreicht, in der eine eigenst{\"a}ndige Rechtspsychologie i.e.S. gegenpartnerisch neben der Vereinigung der hi7fswissenschaftlichen Kriminal- und Forensischen Psychologie existiert.}, subject = {Psychologie}, language = {de} } @inproceedings{Klawitter1985, author = {Klawitter, J{\"o}rg}, title = {Die Diskussion um sozialen Wandel - postmaterielle Werte, ein Beitrag zu einer "Theorie des guten Lebens"?}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-44353}, year = {1985}, abstract = {No abstract available}, subject = {Selbstverwirklichung}, language = {de} }